asiaticoside-7004 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the asiaticoside-7004 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRA1D adrenoceptor alpha 1D
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALDOB aldolase B, fructose-bisphosphate
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APLP2 amyloid beta (A4) precursor-like protein 2
APOD apolipoprotein D
BBS9 Bardet-Biedl syndrome 9
BGN biglycan
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDHR2 cadherin-related family member 2
CDK6 cyclin-dependent kinase 6
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CRYBG3 beta-gamma crystallin domain containing 3
CSTA cystatin A (stefin A)
DIO2 deiodinase, iodothyronine, type II
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNM1 dynamin 1
ENO2 enolase 2 (gamma, neuronal)
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FBXO42 F-box protein 42
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD7 frizzled class receptor 7
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GID4 GID complex subunit 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRX3 glutaredoxin 3
GLS2 glutaminase 2 (liver, mitochondrial)
GLUD2 glutamate dehydrogenase 2
HNF1B HNF1 homeobox B
HNMT histamine N-methyltransferase
HOXC10 homeobox C10
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRF5 interferon regulatory factor 5
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUN jun proto-oncogene
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0355 KIAA0355
KIF5C kinesin family member 5C
KREMEN2 kringle containing transmembrane protein 2
LEPR leptin receptor
LIMK1 LIM domain kinase 1
LINC00302 long intergenic non-protein coding RNA 302
METTL7A methyltransferase like 7A
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PACS1 phosphofurin acidic cluster sorting protein 1
PAX8 paired box 8
PDE12 phosphodiesterase 12
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCH1 phospholipase C, eta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PML promyelocytic leukemia
RAB35 RAB35, member RAS oncogene family
RANBP3 RAN binding protein 3
RRAGD Ras-related GTP binding D
RRBP1 ribosome binding protein 1
RSU1 Ras suppressor protein 1
S1PR4 sphingosine-1-phosphate receptor 4
SAPCD1 suppressor APC domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2B3 SH2B adaptor protein 3
SIPA1 signal-induced proliferation-associated 1
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX13 SRY (sex determining region Y)-box 13
SOX4 SRY (sex determining region Y)-box 4
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPRR2B small proline-rich protein 2B
TBC1D13 TBC1 domain family, member 13
TEAD4 TEA domain family member 4
TM4SF5 transmembrane 4 L six family member 5
TMEM63A transmembrane protein 63A
TRAK1 trafficking protein, kinesin binding 1
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VDAC3 voltage-dependent anion channel 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF574 zinc finger protein 574
ZNF79 zinc finger protein 79
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ABHD17B abhydrolase domain containing 17B
AKAP10 A kinase (PRKA) anchor protein 10
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS1 Bardet-Biedl syndrome 1
BRPF1 bromodomain and PHD finger containing, 1
BSDC1 BSD domain containing 1
BSPRY B-box and SPRY domain containing
C10ORF88 chromosome 10 open reading frame 88
C1ORF56 chromosome 1 open reading frame 56
CCNL2 cyclin L2
CCNT1 cyclin T1
CLDND1 claudin domain containing 1
CORO2A coronin, actin binding protein, 2A
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHDDS dehydrodolichyl diphosphate synthase
DNMBP dynamin binding protein
DOCK1 dedicator of cytokinesis 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EIF5A2 eukaryotic translation initiation factor 5A2
EML4 echinoderm microtubule associated protein like 4
ERO1L ERO1-like (S. cerevisiae)
ETAA1 Ewing tumor-associated antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HTT huntingtin
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRX4 iroquois homeobox 4
JADE3 jade family PHD finger 3
KIAA0556 KIAA0556
KRI1 KRI1 homolog (S. cerevisiae)
KRT8P12 keratin 8 pseudogene 12
LINC00339 long intergenic non-protein coding RNA 339
LMNB2 lamin B2
LRRC20 leucine rich repeat containing 20
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEF1 melanoma antigen family F1
MED24 mediator complex subunit 24
NECAB3 N-terminal EF-hand calcium binding protein 3
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5C 5', 3'-nucleotidase, cytosolic
NUP62CL nucleoporin 62kDa C-terminal like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAN2 PAN2 poly(A) specific ribonuclease subunit
PIBF1 progesterone immunomodulatory binding factor 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTCD2 pentatricopeptide repeat domain 2
RFTN1 raftlin, lipid raft linker 1
RFX7 regulatory factor X, 7
RGS19 regulator of G-protein signaling 19
RIBC2 RIB43A domain with coiled-coils 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SHARPIN SHANK-associated RH domain interactor
SNORA21 small nucleolar RNA, H/ACA box 21
SUGP1 SURP and G patch domain containing 1
SYNGR3 synaptogyrin 3
TCTA T-cell leukemia translocation altered
TMEM2 transmembrane protein 2
TNRC6B trinucleotide repeat containing 6B
TRIM5 tripartite motif containing 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3D tubulin, alpha 3d
TXLNA taxilin alpha
TYK2 tyrosine kinase 2
ULBP2 UL16 binding protein 2
UNC13B unc-13 homolog B (C. elegans)
USP18 ubiquitin specific peptidase 18
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR4 WD repeat domain 4
WDR44 WD repeat domain 44
YIPF3 Yip1 domain family, member 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED8 zinc finger, BED-type containing 8
ZDHHC18 zinc finger, DHHC-type containing 18
ZFAND3 zinc finger, AN1-type domain 3
ZFP30 ZFP30 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF273 zinc finger protein 273
ZNF408 zinc finger protein 408
ZNF611 zinc finger protein 611
ZNF8 zinc finger protein 8