ascorbic acid-3225 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ascorbic acid-3225 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACO2 aconitase 2, mitochondrial
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP26 Rho GTPase activating protein 26
ARMC4 armadillo repeat containing 4
B9D2 B9 protein domain 2
CASP4 caspase 4, apoptosis-related cysteine peptidase
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CELF2 CUGBP, Elav-like family member 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL6A1 collagen, type VI, alpha 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRHR2 corticotropin releasing hormone receptor 2
DEFA4 defensin, alpha 4, corticostatin
DOCK9 dedicator of cytokinesis 9
EDRF1 erythroid differentiation regulatory factor 1
EMC1 ER membrane protein complex subunit 1
FAM189A2 family with sequence similarity 189, member A2
FAM204A family with sequence similarity 204, member A
FAM214B family with sequence similarity 214, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCMR Fc fragment of IgM receptor
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FHIT fragile histidine triad
FSCN3 fascin actin-bundling protein 3, testicular
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR85 G protein-coupled receptor 85
GRB10 growth factor receptor-bound protein 10
GRM3 glutamate receptor, metabotropic 3
HIST1H1T histone cluster 1, H1t
HMOX1 heme oxygenase 1
HOXA7 homeobox A7
HPN hepsin
IFNW1 interferon, omega 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF1C kinesin family member 1C
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAMB4 laminin, beta 4
LATS1 large tumor suppressor kinase 1
LIG3 ligase III, DNA, ATP-dependent
LIMD1 LIM domains containing 1
LTB4R leukotriene B4 receptor
MAP2K5 mitogen-activated protein kinase kinase 5
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MPZ myelin protein zero
MST1L macrophage stimulating 1-like
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NID1 nidogen 1
NTS neurotensin
PAOX polyamine oxidase (exo-N4-amino)
PIPOX pipecolic acid oxidase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLLP plasmolipin
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PSD3 pleckstrin and Sec7 domain containing 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB3B RAB3B, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RGS2 regulator of G-protein signaling 2
RIMS2 regulating synaptic membrane exocytosis 2
SCAND2P SCAN domain containing 2 pseudogene
SCRN3 secernin 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT5 sirtuin 5
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLMO1 slowmo homolog 1 (Drosophila)
SLN sarcolipin
SMAD4 SMAD family member 4
SPAG6 sperm associated antigen 6
SPRR1A small proline-rich protein 1A
SSPN sarcospan
STK17B serine/threonine kinase 17b
TGFB1 transforming growth factor, beta 1
TLK1 tousled-like kinase 1
TLR5 toll-like receptor 5
TMPRSS4 transmembrane protease, serine 4
TOR4A torsin family 4, member A
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF3IP3 TRAF3 interacting protein 3
TRIB2 tribbles pseudokinase 2
TSC22D2 TSC22 domain family, member 2
TYRP1 tyrosinase-related protein 1
UBXN1 UBX domain protein 1
WDFY3 WD repeat and FYVE domain containing 3
XDH xanthine dehydrogenase
ZNF230 zinc finger protein 230
ZNF334 zinc finger protein 334
ZNF440 zinc finger protein 440
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P3 annexin A2 pseudogene 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP4 bone morphogenetic protein 4
C1ORF159 chromosome 1 open reading frame 159
C22ORF46 chromosome 22 open reading frame 46
C8ORF60 chromosome 8 open reading frame 60
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC25 coiled-coil domain containing 25
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDON cell adhesion associated, oncogene regulated
CES1 carboxylesterase 1
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CGA glycoprotein hormones, alpha polypeptide
CLSTN2 calsyntenin 2
CNGB3 cyclic nucleotide gated channel beta 3
CRLF1 cytokine receptor-like factor 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP13 dual specificity phosphatase 13
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FADS2 fatty acid desaturase 2
FAM192A family with sequence similarity 192, member A
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GBP2 guanylate binding protein 2, interferon-inducible
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HDAC4 histone deacetylase 4
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1B histone cluster 1, H1b
HIST1H2AL histone cluster 1, H2al
HMHA1 histocompatibility (minor) HA-1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC11 homeobox C11
HOXC5 homeobox C5
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0319L KIAA0319-like
LDHB lactate dehydrogenase B
LIME1 Lck interacting transmembrane adaptor 1
LINC00339 long intergenic non-protein coding RNA 339
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC730101 uncharacterized LOC730101
LYZ lysozyme
MANBA mannosidase, beta A, lysosomal
MAP9 microtubule-associated protein 9
MFSD12 major facilitator superfamily domain containing 12
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYO1E myosin IE
NBEAL2 neurobeachin-like 2
NLGN1 neuroligin 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NUPL2 nucleoporin like 2
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PC pyruvate carboxylase
PODNL1 podocan-like 1
POMT2 protein-O-mannosyltransferase 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB11B RAB11B, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFTN1 raftlin, lipid raft linker 1
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPAG4 sperm associated antigen 4
SREK1IP1 SREK1-interacting protein 1
STAB2 stabilin 2
STBD1 starch binding domain 1
STX1A syntaxin 1A (brain)
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM21 tripartite motif containing 21
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
WDR33 WD repeat domain 33
WNT10B wingless-type MMTV integration site family, member 10B
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF205 zinc finger protein 205
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701
ZSCAN26 zinc finger and SCAN domain containing 26