artery disease Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A vascular disease that is located_in an artery. (Human Disease Ontology, DOID_0050828)
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Genes

185 genes associated with the disease artery disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FGG fibrinogen gamma chain 1.29797
FGA fibrinogen alpha chain 1.08375
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.730451
APOC1 apolipoprotein C-I 0.664868
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.414345
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.378715
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.34256
FGB fibrinogen beta chain 0.34256
PHACTR1 phosphatase and actin regulator 1 0.262454
PLRG1 pleiotropic regulator 1 0.246694
MMP3 matrix metallopeptidase 3 0.161011
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.010688
RPL6 ribosomal protein L6 0.010605
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.010551
ICAM1 intercellular adhesion molecule 1 0.010525
ZFPM2 zinc finger protein, FOG family member 2 0.010516
PDGFD platelet derived growth factor D 0.009932
SYK spleen tyrosine kinase 0.009751
PLG plasminogen 0.009653
RNF213 ring finger protein 213 0.009475
LPA lipoprotein, Lp(a) 0.009454
CSK c-src tyrosine kinase 0.009368
PSRC1 proline/serine-rich coiled-coil 1 0.009188
FGF5 fibroblast growth factor 5 0.009073
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.008728
C5ORF56 chromosome 5 open reading frame 56 0.008572
DCHS2 dachsous cadherin-related 2 0.00848
ARHGAP42 Rho GTPase activating protein 42 0.00835
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00835
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 0.008098
IL6R interleukin 6 receptor 0.008098
LDLR low density lipoprotein receptor 0.008023
TWIST1 twist family bHLH transcription factor 1 0.007999
RAB37 RAB37, member RAS oncogene family 0.007814
CD300LF CD300 molecule-like family member f 0.007814
NT5C2 5'-nucleotidase, cytosolic II 0.007765
HFE hemochromatosis 0.00766
CBS cystathionine-beta-synthase 0.007491
PCCB propionyl CoA carboxylase, beta polypeptide 0.007307
SH2B3 SH2B adaptor protein 3 0.007152
VMP1 vacuole membrane protein 1 0.006766
LOC340340 uncharacterized LOC340340 0.006713
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.006558
COL4A2 collagen, type IV, alpha 2 0.006333
NLRP3 NLR family, pyrin domain containing 3 0.006276
SCARB1 scavenger receptor class B, member 1 0.006276
HIST1H1T histone cluster 1, H1t 0.006046
ADM adrenomedullin 0.005911
CETP cholesteryl ester transfer protein, plasma 0.005728
ZPR1 ZPR1 zinc finger 0.005584
EBF1 early B-cell factor 1 0.0055
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene 0.005457
COL4A1 collagen, type IV, alpha 1 0.005457
BAG6 BCL2-associated athanogene 6 0.00523
HDAC9 histone deacetylase 9 0.00523
C12ORF42 chromosome 12 open reading frame 42 0.005052
UMOD uromodulin 0.004961
FIGN fidgetin 0.004961
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 0.004882
MRPS6 mitochondrial ribosomal protein S6 0.004803
APOB apolipoprotein B 0.00464
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.004594
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.004594
GOSR2 golgi SNAP receptor complex member 2 0.004594
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.004385
CPLX3 complexin 3 0.004303
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.004303
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.004205
ABI2 abl-interactor 2 0.004205
BARHL2 BarH-like homeobox 2 0.003634
MIA3 melanoma inhibitory activity family, member 3 0.003634
AP3B2 adaptor-related protein complex 3, beta 2 subunit 0.003634
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.003634
MOV10 Mov10 RISC complex RNA helicase 0.003634
C10ORF107 chromosome 10 open reading frame 107 0.003634
NINJ2 ninjurin 2 0.003634
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.003409
ADRB1 adrenoceptor beta 1 0.00335
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.00335
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.00335
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.003208
WDFY4 WDFY family member 4 0.003208
ULK4 unc-51 like kinase 4 0.003184
NOV nephroblastoma overexpressed 0.003067
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.003067
PLCE1 phospholipase C, epsilon 1 0.002977
PCSK2 proprotein convertase subtilisin/kexin type 2 0.002963
CXCL12 chemokine (C-X-C motif) ligand 12 0.002854
POC1B POC1 centriolar protein B 0.002854
C20ORF196 chromosome 20 open reading frame 196 0.002805
LPAR3 lysophosphatidic acid receptor 3 0.002805
CDK14 cyclin-dependent kinase 14 0.002805
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.002762
PLCD3 phospholipase C, delta 3 0.002723
WDR12 WD repeat domain 12 0.002723
RPL21P44 ribosomal protein L21 pseudogene 44 0.002723
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.002723
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.002723
GCKR glucokinase (hexokinase 4) regulator 0.002682
DNAH5 dynein, axonemal, heavy chain 5 0.002682
RNF157 ring finger protein 157 0.002682
NUMB numb homolog (Drosophila) 0.002582
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.002497
ATXN2 ataxin 2 0.002469
ZFHX3 zinc finger homeobox 3 0.002469
NPR3 natriuretic peptide receptor 3 0.002469
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.002359
LRRC7 leucine rich repeat containing 7 0.00232
MAP4 microtubule-associated protein 4 0.00232
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00232
FES FES proto-oncogene, tyrosine kinase 0.00232
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.002148
ASB3 ankyrin repeat and SOCS box containing 3 0.002148
FSTL4 follistatin-like 4 0.001967
TRAFD1 TRAF-type zinc finger domain containing 1 0.001935
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.001935
MECOM MDS1 and EVI1 complex locus 0.001935
BRAP BRCA1 associated protein 0.001722
ZNF652 zinc finger protein 652 0.001722
STK39 serine threonine kinase 39 0.001722
CASZ1 castor zinc finger 1 0.001722
PARP14 poly (ADP-ribose) polymerase family, member 14 0.001722
ZNF831 zinc finger protein 831 0.001722
MARC1 mitochondrial amidoxime reducing component 1 0.001598
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.001598
TMEM212 transmembrane protein 212 0.001523
RCSD1 RCSD domain containing 1 0.001468
ITGA9 integrin, alpha 9 0.001468
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.001468
PRKCH protein kinase C, eta 0.001468
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 0.001423
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.001385
C2ORF88 chromosome 2 open reading frame 88 0.001385
MYO16 myosin XVI 0.001385
FBN1 fibrillin 1 0.001361
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.001324
CLEC14A C-type lectin domain family 14, member A 0.001324
RGS1 regulator of G-protein signaling 1 0.001324
RGMA repulsive guidance molecule family member a 0.001298
PRRX1 paired related homeobox 1 0.001298
RP1 retinitis pigmentosa 1 (autosomal dominant) 0.001298
RBBP8 retinoblastoma binding protein 8 0.001298
SYNRG synergin, gamma 0.001128
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.001128
TENM1 teneurin transmembrane protein 1 0.001128
JAKMIP1 janus kinase and microtubule interacting protein 1 0.001128
GPR83 G protein-coupled receptor 83 0.001128
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.001128
FRY furry homolog (Drosophila) 0.001128
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.001035
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.001035
DLG2 discs, large homolog 2 (Drosophila) 0.001035
LZTS1 leucine zipper, putative tumor suppressor 1 0.001035
MSRA methionine sulfoxide reductase A 9.81E-4
SETBP1 SET binding protein 1 9.81E-4
KDM4A lysine (K)-specific demethylase 4A 9.81E-4
MYO1D myosin ID 9.4E-4
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 9.4E-4
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 9.4E-4
C3ORF56 chromosome 3 open reading frame 56 9.05E-4
IQSEC3 IQ motif and Sec7 domain 3 9.05E-4
MEOX2 mesenchyme homeobox 2 9.05E-4
PCGF5 polycomb group ring finger 5 9.05E-4
EYA4 EYA transcriptional coactivator and phosphatase 4 9.05E-4
TMC7 transmembrane channel-like 7 9.05E-4
ADCY8 adenylate cyclase 8 (brain) 8.77E-4
BMPR1B bone morphogenetic protein receptor, type IB 8.77E-4
IDI2 isopentenyl-diphosphate delta isomerase 2 8.52E-4
IGFBPL1 insulin-like growth factor binding protein-like 1 8.52E-4
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 8.29E-4
KIAA0020 KIAA0020 8.29E-4
AIM1 absent in melanoma 1 8.29E-4
RPL14P1 ribosomal protein L14 pseudogene 1 8.29E-4
SOX17 SRY (sex determining region Y)-box 17 8.1E-4
DAB2IP DAB2 interacting protein 6.6E-4
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 6.14E-4
STARD13 StAR-related lipid transfer (START) domain containing 13 5.4E-4
EDNRA endothelin receptor type A 4.6E-4
BOLL boule-like RNA-binding protein 3.72E-4
SF3B1 splicing factor 3b, subunit 1, 155kDa 3.32E-4
ANKRD44 ankyrin repeat domain 44 3.02E-4
PLCL1 phospholipase C-like 1 2.84E-4
LTA lymphotoxin alpha 1.9E-4
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.9E-4
GPR137B G protein-coupled receptor 137B 1.59E-4