arteriosclerosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries. (Human Disease Ontology, DOID_2349)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003991
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Genes

22 gene mutations causing the arteriosclerosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
CSF1 colony stimulating factor 1 (macrophage)
HPS1 Hermansky-Pudlak syndrome 1
HPS4 Hermansky-Pudlak syndrome 4
HPS5 Hermansky-Pudlak syndrome 5
KL klotho
KLF15 Kruppel-like factor 15
LDLR low density lipoprotein receptor
MPO myeloperoxidase
NOS2 nitric oxide synthase 2, inducible
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PLA2G15 phospholipase A2, group XV
PON1 paraoxonase 1
PON2 paraoxonase 2
PRKCD protein kinase C, delta
RORA RAR-related orphan receptor A
SCARB1 scavenger receptor class B, member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SPP1 secreted phosphoprotein 1
TK1 thymidine kinase 1, soluble
TLR4 toll-like receptor 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4