arteriosclerosis Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries. (Human Disease Ontology, DOID_2349)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0002634
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Genes

82 genes associated with the arteriosclerosis phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACTA2 actin, alpha 2, smooth muscle, aorta
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGXT alanine-glyoxylate aminotransferase
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
ANTXR1 anthrax toxin receptor 1
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
BANF1 barrier to autointegration factor 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C4A complement component 4A (Rodgers blood group)
CALR calreticulin
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CLIP2 CAP-GLY domain containing linker protein 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
ELN elastin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GGCX gamma-glutamyl carboxylase
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HGD homogentisate 1,2-dioxygenase
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HTRA1 HtrA serine peptidase 1
IDUA iduronidase, alpha-L-
IL10 interleukin 10
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
JAK2 Janus kinase 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LCAT lecithin-cholesterol acyltransferase
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LIMK1 LIM domain kinase 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPC lipase, hepatic
LMNA lamin A/C
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
MEFV Mediterranean fever
MLX MLX, MAX dimerization protein
MPL MPL proto-oncogene, thrombopoietin receptor
MYH11 myosin, heavy chain 11, smooth muscle
MYH9 myosin, heavy chain 9, non-muscle
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH3 notch 3
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
PPARG peroxisome proliferator-activated receptor gamma
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RFC2 replication factor C (activator 1) 2, 40kDa
SC5D sterol-C5-desaturase
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SH2B3 SH2B adaptor protein 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
STAT4 signal transducer and activator of transcription 4
TBL2 transducin (beta)-like 2
TET2 tet methylcytosine dioxygenase 2
TLR4 toll-like receptor 4
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNXB tenascin XB
TP53 tumor protein p53
WRN Werner syndrome, RecQ helicase-like
ZMPSTE24 zinc metallopeptidase STE24