arteriosclerosis Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries. (Human Disease Ontology, DOID_2349)
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Genes

60 genes associated with the disease arteriosclerosis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FGG fibrinogen gamma chain 2.66306
FGA fibrinogen alpha chain 2.54174
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 2.33658
APOC1 apolipoprotein C-I 2.26733
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.08132
FGB fibrinogen beta chain 2.0208
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.0208
PLRG1 pleiotropic regulator 1 1.92766
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.88852
MMP3 matrix metallopeptidase 3 1.86151
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.51016
ICAM1 intercellular adhesion molecule 1 1.49392
ZFPM2 zinc finger protein, FOG family member 2 1.48894
PHACTR1 phosphatase and actin regulator 1 1.45255
PDGFD platelet derived growth factor D 1.27521
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.24299
PLG plasminogen 1.2206
LPA lipoprotein, Lp(a) 1.14929
PSRC1 proline/serine-rich coiled-coil 1 1.06123
C5ORF56 chromosome 5 open reading frame 56 0.894262
DCHS2 dachsous cadherin-related 2 0.872896
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 0.790827
IL6R interleukin 6 receptor 0.790827
LDLR low density lipoprotein receptor 0.774217
SYK spleen tyrosine kinase 0.738873
RAB37 RAB37, member RAS oncogene family 0.73332
CD300LF CD300 molecule-like family member f 0.73332
CBS cystathionine-beta-synthase 0.682635
PCCB propionyl CoA carboxylase, beta polypeptide 0.65413
VMP1 vacuole membrane protein 1 0.58494
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.572184
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.561725
NLRP3 NLR family, pyrin domain containing 3 0.52461
SCARB1 scavenger receptor class B, member 1 0.52461
CETP cholesteryl ester transfer protein, plasma 0.464771
ZPR1 ZPR1 zinc finger 0.449873
COL4A1 collagen, type IV, alpha 1 0.438544
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene 0.438544
APOB apolipoprotein B 0.368757
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.345945
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.327313
ABI2 abl-interactor 2 0.327313
COL4A2 collagen, type IV, alpha 2 0.264872
AP3B2 adaptor-related protein complex 3, beta 2 subunit 0.256228
BARHL2 BarH-like homeobox 2 0.256228
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.256228
WDFY4 WDFY family member 4 0.197766
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.197766
RNF213 ring finger protein 213 0.15771
PCSK2 proprotein convertase subtilisin/kexin type 2 0.15771
CDK14 cyclin-dependent kinase 14 0.126165
LPAR3 lysophosphatidic acid receptor 3 0.126165
C20ORF196 chromosome 20 open reading frame 196 0.126165
DNAH5 dynein, axonemal, heavy chain 5 0.100789
RNF157 ring finger protein 157 0.100789
GCKR glucokinase (hexokinase 4) regulator 0.100789
NUMB numb homolog (Drosophila) 0.080593
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 0.064973
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.064973
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.043246