artemisinin-7007 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the artemisinin-7007 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AKAP11 A kinase (PRKA) anchor protein 11
AKAP12 A kinase (PRKA) anchor protein 12
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AQR aquarius intron-binding spliceosomal factor
ARHGAP35 Rho GTPase activating protein 35
ARTN artemin
ATN1 atrophin 1
BTBD2 BTB (POZ) domain containing 2
C17ORF59 chromosome 17 open reading frame 59
CACFD1 calcium channel flower domain containing 1
CALD1 caldesmon 1
CCP110 centriolar coiled coil protein 110kDa
CCR2 chemokine (C-C motif) receptor 2
CD1C CD1c molecule
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CLCN7 chloride channel, voltage-sensitive 7
CRY2 cryptochrome circadian clock 2
CSF1R colony stimulating factor 1 receptor
CTBP2 C-terminal binding protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
DGKG diacylglycerol kinase, gamma 90kDa
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FER fer (fps/fes related) tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FOLR1 folate receptor 1 (adult)
GLTSCR1L GLTSCR1-like
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRB7 growth factor receptor-bound protein 7
GRM8 glutamate receptor, metabotropic 8
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAP1 huntingtin-associated protein 1
HSF1 heat shock transcription factor 1
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IGHMBP2 immunoglobulin mu binding protein 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL11 interleukin 11
ING4 inhibitor of growth family, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT17 keratin 17, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC257152 uncharacterized LOC257152
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LST1 leukocyte specific transcript 1
MAOA monoamine oxidase A
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MED25 mediator complex subunit 25
MUC5B mucin 5B, oligomeric mucus/gel-forming
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NF1 neurofibromin 1
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NR2E3 nuclear receptor subfamily 2, group E, member 3
OTUD3 OTU deubiquitinase 3
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAX2 paired box 2
PDK2 pyruvate dehydrogenase kinase, isozyme 2
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPARA peroxisome proliferator-activated receptor alpha
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PVR poliovirus receptor
R3HDM1 R3H domain containing 1
SAMD9 sterile alpha motif domain containing 9
SBF1 SET binding factor 1
SCAI suppressor of cancer cell invasion
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIX1 SIX homeobox 1
SLC38A7 solute carrier family 38, member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX4 SRY (sex determining region Y)-box 4
SPATA1 spermatogenesis associated 1
SYCP1 synaptonemal complex protein 1
TAOK1 TAO kinase 1
TBCD tubulin folding cofactor D
TFF2 trefoil factor 2
TLE4 transducin-like enhancer of split 4
TMPRSS4 transmembrane protease, serine 4
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM10 tripartite motif containing 10
TTC28 tetratricopeptide repeat domain 28
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA3C tubulin, alpha 3c
UBXN1 UBX domain protein 1
VIM vimentin
ZER1 zyg-11 related, cell cycle regulator
ZNF37BP zinc finger protein 37B, pseudogene
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD14A abhydrolase domain containing 14A
ADAM15 ADAM metallopeptidase domain 15
AGO3 argonaute RISC catalytic component 3
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANO10 anoctamin 10
ANXA1 annexin A1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAD3A ATPase family, AAA domain containing 3A
ATP13A2 ATPase type 13A2
BCORL1 BCL6 corepressor-like 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC88C coiled-coil domain containing 88C
CCNE1 cyclin E1
CDC37L1 cell division cycle 37-like 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPQ centromere protein Q
CISH cytokine inducible SH2-containing protein
CMTR1 cap methyltransferase 1
COCH cochlin
COQ6 coenzyme Q6 monooxygenase
CPTP ceramide-1-phosphate transfer protein
CRYL1 crystallin, lambda 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DND1 DND microRNA-mediated repression inhibitor 1
EIF5A2 eukaryotic translation initiation factor 5A2
GALK1 galactokinase 1
GLCE glucuronic acid epimerase
GMIP GEM interacting protein
GTPBP2 GTP binding protein 2
GYS1 glycogen synthase 1 (muscle)
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
HPSE heparanase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL15RA interleukin 15 receptor, alpha
IRF7 interferon regulatory factor 7
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0556 KIAA0556
KLHL26 kelch-like family member 26
KRI1 KRI1 homolog (S. cerevisiae)
KRT13 keratin 13, type I
LAMB2 laminin, beta 2 (laminin S)
LRRC61 leucine rich repeat containing 61
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MED24 mediator complex subunit 24
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTCL1 microtubule crosslinking factor 1
NBEAL2 neurobeachin-like 2
NDRG1 N-myc downstream regulated 1
NES nestin
NKAIN1 Na+/K+ transporting ATPase interacting 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB3 protocadherin beta 3
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPCS phosphopantothenoylcysteine synthetase
PQLC1 PQ loop repeat containing 1
PRKX protein kinase, X-linked
QTRT1 queuine tRNA-ribosyltransferase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RCOR3 REST corepressor 3
REEP4 receptor accessory protein 4
RFTN1 raftlin, lipid raft linker 1
RNF123 ring finger protein 123
RPL13P5 ribosomal protein L13 pseudogene 5
RPP25 ribonuclease P/MRP 25kDa subunit
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
S100A4 S100 calcium binding protein A4
SETD8 SET domain containing (lysine methyltransferase) 8
SF3A3 splicing factor 3a, subunit 3, 60kDa
SLC10A3 solute carrier family 10, member 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC46A3 solute carrier family 46, member 3
SOX12 SRY (sex determining region Y)-box 12
TCTA T-cell leukemia translocation altered
TM7SF3 transmembrane 7 superfamily member 3
TMEM115 transmembrane protein 115
TMEM2 transmembrane protein 2
TMEM39B transmembrane protein 39B
TMEM57 transmembrane protein 57
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR4 WD repeat domain 4
WDR60 WD repeat domain 60
ZNF586 zinc finger protein 586
ZNF816 zinc finger protein 816