arachidonic acid-604 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the arachidonic acid-604 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP8L A kinase (PRKA) anchor protein 8-like
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AQP3 aquaporin 3 (Gill blood group)
AQP8 aquaporin 8
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASCL1 achaete-scute family bHLH transcription factor 1
ASIC1 acid sensing (proton gated) ion channel 1
ATF6 activating transcription factor 6
ATXN8OS ATXN8 opposite strand (non-protein coding)
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BPHL biphenyl hydrolase-like (serine hydrolase)
C10ORF76 chromosome 10 open reading frame 76
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLIC4 chloride intracellular channel 4
CNTFR ciliary neurotrophic factor receptor
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CSRP2 cysteine and glycine-rich protein 2
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DBP D site of albumin promoter (albumin D-box) binding protein
DCN decorin
DENND3 DENN/MADD domain containing 3
DLG3 discs, large homolog 3 (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DPYSL3 dihydropyrimidinase-like 3
ELF4 E74-like factor 4 (ets domain transcription factor)
GLS glutaminase
GM2A GM2 ganglioside activator
GREB1L growth regulation by estrogen in breast cancer-like
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
HLA-G major histocompatibility complex, class I, G
HMX1 H6 family homeobox 1
HNF4A hepatocyte nuclear factor 4, alpha
HSDL2 hydroxysteroid dehydrogenase like 2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL15RA interleukin 15 receptor, alpha
KHNYN KH and NYN domain containing
KIAA0040 KIAA0040
KIF2A kinesin heavy chain member 2A
KLHL28 kelch-like family member 28
KLK8 kallikrein-related peptidase 8
KRT13 keratin 13, type I
LOC647070 uncharacterized LOC647070
MAGED2 melanoma antigen family D2
MAGT1 magnesium transporter 1
MAML3 mastermind-like 3 (Drosophila)
MAST2 microtubule associated serine/threonine kinase 2
MMP19 matrix metallopeptidase 19
MTUS1 microtubule associated tumor suppressor 1
NACA nascent polypeptide-associated complex alpha subunit
NCKIPSD NCK interacting protein with SH3 domain
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX8 paired box 8
PCDHB3 protocadherin beta 3
PEX19 peroxisomal biogenesis factor 19
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
PTRF polymerase I and transcript release factor
RAB11B RAB11B, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RBMS2 RNA binding motif, single stranded interacting protein 2
RECQL4 RecQ protein-like 4
RNF126 ring finger protein 126
RNFT2 ring finger protein, transmembrane 2
RPL10 ribosomal protein L10
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A1 S100 calcium binding protein A1
SAPCD1 suppressor APC domain containing 1
SCLY selenocysteine lyase
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLCO3A1 solute carrier organic anion transporter family, member 3A1
STARD5 StAR-related lipid transfer (START) domain containing 5
STX12 syntaxin 12
SUGP2 SURP and G patch domain containing 2
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SUSD4 sushi domain containing 4
T T, brachyury homolog (mouse)
TBC1D2B TBC1 domain family, member 2B
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTLL4 tubulin tyrosine ligase-like family member 4
UBE2I ubiquitin-conjugating enzyme E2I
USP34 ubiquitin specific peptidase 34
VPREB3 pre-B lymphocyte 3
WDR48 WD repeat domain 48
ZBED1 zinc finger, BED-type containing 1
ZMYM6 zinc finger, MYM-type 6
ZNF473 zinc finger protein 473
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP11A Rho GTPase activating protein 11A
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C2ORF27A chromosome 2 open reading frame 27A
CA11 carbonic anhydrase XI
CA7 carbonic anhydrase VII
CAV3 caveolin 3
CCDC71 coiled-coil domain containing 71
CCK cholecystokinin
CDH18 cadherin 18, type 2
CDHR2 cadherin-related family member 2
CETN1 centrin, EF-hand protein, 1
CHKB choline kinase beta
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN2 chloride channel, voltage-sensitive 2
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CRMP1 collapsin response mediator protein 1
CSAD cysteine sulfinic acid decarboxylase
CXCL10 chemokine (C-X-C motif) ligand 10
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DUSP22 dual specificity phosphatase 22
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMILIN2 elastin microfibril interfacer 2
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM188A family with sequence similarity 188, member A
FAM192A family with sequence similarity 192, member A
FAM63A family with sequence similarity 63, member A
FGF6 fibroblast growth factor 6
FGL1 fibrinogen-like 1
GAB2 GRB2-associated binding protein 2
GBP2 guanylate binding protein 2, interferon-inducible
GCKR glucokinase (hexokinase 4) regulator
GJC1 gap junction protein, gamma 1, 45kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRAMD1B GRAM domain containing 1B
GRB7 growth factor receptor-bound protein 7
HAND1 heart and neural crest derivatives expressed 1
HHLA1 HERV-H LTR-associating 1
IGSF1 immunoglobulin superfamily, member 1
IL22RA1 interleukin 22 receptor, alpha 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JMJD4 jumonji domain containing 4
JOSD1 Josephin domain containing 1
KIFC3 kinesin family member C3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LIAS lipoic acid synthetase
LPPR1 lipid phosphate phosphatase-related protein type 1
MARC1 mitochondrial amidoxime reducing component 1
MT3 metallothionein 3
MYO1E myosin IE
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NMRK2 nicotinamide riboside kinase 2
NRSN2 neurensin 2
OLFML2B olfactomedin-like 2B
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PF4 platelet factor 4
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PISD phosphatidylserine decarboxylase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROL1 proline rich, lacrimal 1
PRPH peripherin
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RNF208 ring finger protein 208
SDC3 syndecan 3
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMO smoothened, frizzled class receptor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAC SH3 and cysteine rich domain
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TENM4 teneurin transmembrane protein 4
TINAGL1 tubulointerstitial nephritis antigen-like 1
TNNT3 troponin T type 3 (skeletal, fast)
TNS2 tensin 2
TSHB thyroid stimulating hormone, beta
TSHZ2 teashirt zinc finger homeobox 2
ULBP1 UL16 binding protein 1
WDR19 WD repeat domain 19
WNT10B wingless-type MMTV integration site family, member 10B
WNT7A wingless-type MMTV integration site family, member 7A
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB22 zinc finger and BTB domain containing 22
ZCCHC2 zinc finger, CCHC domain containing 2
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF33B zinc finger protein 33B
ZNF35 zinc finger protein 35
ZNF770 zinc finger protein 770