arachidonic acid-443 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the arachidonic acid-443 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAM20 ADAM metallopeptidase domain 20
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALAD aminolevulinate dehydratase
ANXA2P3 annexin A2 pseudogene 3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARRB2 arrestin, beta 2
ASCL1 achaete-scute family bHLH transcription factor 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BRCA1 breast cancer 1, early onset
BTBD2 BTB (POZ) domain containing 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD80 CD80 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CLK3 CDC-like kinase 3
CNTN1 contactin 1
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CSH2 chorionic somatomammotropin hormone 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNASE1L1 deoxyribonuclease I-like 1
DSC2 desmocollin 2
ECI2 enoyl-CoA delta isomerase 2
EFNB3 ephrin-B3
ELF1 E74-like factor 1 (ets domain transcription factor)
ELMO2 engulfment and cell motility 2
EMC1 ER membrane protein complex subunit 1
EPS8L1 EPS8-like 1
ESR1 estrogen receptor 1
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FGF4 fibroblast growth factor 4
FRMD1 FERM domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB2 glucocorticoid modulatory element binding protein 2
GML glycosylphosphatidylinositol anchored molecule like
GOLGA1 golgin A1
GREB1 growth regulation by estrogen in breast cancer 1
GSK3A glycogen synthase kinase 3 alpha
HBB hemoglobin, beta
HIST1H3G histone cluster 1, H3g
HPS4 Hermansky-Pudlak syndrome 4
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
ICAM1 intercellular adhesion molecule 1
JAK2 Janus kinase 2
KHNYN KH and NYN domain containing
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
LARP7 La ribonucleoprotein domain family, member 7
LBP lipopolysaccharide binding protein
MED16 mediator complex subunit 16
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NDRG4 NDRG family member 4
NOD1 nucleotide-binding oligomerization domain containing 1
NPY neuropeptide Y
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OASL 2'-5'-oligoadenylate synthetase-like
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PARVA parvin, alpha
PGK1 phosphoglycerate kinase 1
PKNOX2 PBX/knotted 1 homeobox 2
PLCG1 phospholipase C, gamma 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POT1 protection of telomeres 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBM5 RNA binding motif protein 5
RCAN1 regulator of calcineurin 1
REEP1 receptor accessory protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS11 ribosomal protein S11
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3GL3 SH3-domain GRB2-like 3
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SNX19 sorting nexin 19
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D16 TBC1 domain family, member 16
TECPR2 tectonin beta-propeller repeat containing 2
THOC1 THO complex 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIP11 thyroid hormone receptor interactor 11
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTLL4 tubulin tyrosine ligase-like family member 4
TUBA4B tubulin, alpha 4b
TULP3 tubby like protein 3
WTAP Wilms tumor 1 associated protein
YIPF2 Yip1 domain family, member 2
YLPM1 YLP motif containing 1
ZBTB40 zinc finger and BTB domain containing 40

decreased expression

Symbol Name
ADM2 adrenomedullin 2
AGPS alkylglycerone phosphate synthase
AHR aryl hydrocarbon receptor
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
ASGR2 asialoglycoprotein receptor 2
BBS1 Bardet-Biedl syndrome 1
BEAN1 brain expressed, associated with NEDD4, 1
BIRC7 baculoviral IAP repeat containing 7
BPGM 2,3-bisphosphoglycerate mutase
C16ORF59 chromosome 16 open reading frame 59
CBR4 carbonyl reductase 4
CCDC94 coiled-coil domain containing 94
CCR8 chemokine (C-C motif) receptor 8
CDH22 cadherin 22, type 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EGLN3 egl-9 family hypoxia-inducible factor 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM46C family with sequence similarity 46, member C
FGD6 FYVE, RhoGEF and PH domain containing 6
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUZ fuzzy planar cell polarity protein
GLDC glycine dehydrogenase (decarboxylating)
GMEB1 glucocorticoid modulatory element binding protein 1
GPC3 glypican 3
GPR176 G protein-coupled receptor 176
HAO2 hydroxyacid oxidase 2 (long chain)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIRIP3 HIRA interacting protein 3
HOXA5 homeobox A5
IRS4 insulin receptor substrate 4
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JAM2 junctional adhesion molecule 2
JOSD1 Josephin domain containing 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIN Kin17 DNA and RNA binding protein
KLHL3 kelch-like family member 3
KRT32 keratin 32, type I
LAMB2 laminin, beta 2 (laminin S)
LGALS13 lectin, galactoside-binding, soluble, 13
LOC257152 uncharacterized LOC257152
LOC729164 hCG1732469
MAOB monoamine oxidase B
MARC1 mitochondrial amidoxime reducing component 1
MBIP MAP3K12 binding inhibitory protein 1
MBNL3 muscleblind-like splicing regulator 3
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MTERF4 mitochondrial transcription termination factor 4
MTMR11 myotubularin related protein 11
MYO1F myosin IF
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NT5DC3 5'-nucleotidase domain containing 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP93 nucleoporin 93kDa
NUPL2 nucleoporin like 2
OTUD3 OTU deubiquitinase 3
PARG poly (ADP-ribose) glycohydrolase
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PFDN1 prefoldin subunit 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIPOX pipecolic acid oxidase
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
PPCDC phosphopantothenoylcysteine decarboxylase
PRODH proline dehydrogenase (oxidase) 1
PVRIG poliovirus receptor related immunoglobulin domain containing
RANBP17 RAN binding protein 17
RLBP1 retinaldehyde binding protein 1
RLN2 relaxin 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SAC3D1 SAC3 domain containing 1
SCIN scinderin
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLN sarcolipin
SNHG20 small nucleolar RNA host gene 20
SOAT1 sterol O-acyltransferase 1
STMN4 stathmin-like 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TIMP2 TIMP metallopeptidase inhibitor 2
TMSB15A thymosin beta 15a
TMSB4Y thymosin beta 4, Y-linked
UCKL1 uridine-cytidine kinase 1-like 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VIM vimentin
ZFP36 ZFP36 ring finger protein