arachidonic acid-441 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the arachidonic acid-441 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP8L A kinase (PRKA) anchor protein 8-like
ALAD aminolevulinate dehydratase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARRB2 arrestin, beta 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATF6 activating transcription factor 6
AVL9 AVL9 homolog (S. cerevisiase)
B3GAT3 beta-1,3-glucuronyltransferase 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAHCC1 BAH domain and coiled-coil containing 1
BICD1 bicaudal D homolog 1 (Drosophila)
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C14ORF1 chromosome 14 open reading frame 1
C1ORF159 chromosome 1 open reading frame 159
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAV3 caveolin 3
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC85C coiled-coil domain containing 85C
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CEP170 centrosomal protein 170kDa
CEP192 centrosomal protein 192kDa
CEP72 centrosomal protein 72kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHPF2 chondroitin polymerizing factor 2
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
DENND4C DENN/MADD domain containing 4C
DIEXF digestive organ expansion factor homolog (zebrafish)
DNM2 dynamin 2
DSTYK dual serine/threonine and tyrosine protein kinase
ECI2 enoyl-CoA delta isomerase 2
EPN3 epsin 3
EPS8L1 EPS8-like 1
ESR1 estrogen receptor 1
FAM162A family with sequence similarity 162, member A
FAM174B family with sequence similarity 174, member B
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FCHSD2 FCH and double SH3 domains 2
FGF4 fibroblast growth factor 4
FRMD1 FERM domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GMEB2 glucocorticoid modulatory element binding protein 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRB7 growth factor receptor-bound protein 7
GSK3A glycogen synthase kinase 3 alpha
HBB hemoglobin, beta
HIST1H3G histone cluster 1, H3g
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IDUA iduronidase, alpha-L-
IL1B interleukin 1, beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INA internexin neuronal intermediate filament protein, alpha
JAK2 Janus kinase 2
KLF6 Kruppel-like factor 6
LBP lipopolysaccharide binding protein
LINC00574 long intergenic non-protein coding RNA 574
LMBR1L limb development membrane protein 1-like
NDRG4 NDRG family member 4
NF2 neurofibromin 2 (merlin)
NOD1 nucleotide-binding oligomerization domain containing 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PHKA2 phosphorylase kinase, alpha 2 (liver)
PKNOX2 PBX/knotted 1 homeobox 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTPRA protein tyrosine phosphatase, receptor type, A
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RBM5 RNA binding motif protein 5
RCAN1 regulator of calcineurin 1
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS11 ribosomal protein S11
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
STX2 syntaxin 2
TBC1D16 TBC1 domain family, member 16
TBL1X transducin (beta)-like 1X-linked
TCTN1 tectonic family member 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TRIM27 tripartite motif containing 27
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TULP3 tubby like protein 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
WDHD1 WD repeat and HMG-box DNA binding protein 1
WIZ widely interspaced zinc finger motifs
YIPF2 Yip1 domain family, member 2
YLPM1 YLP motif containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZBTB7A zinc finger and BTB domain containing 7A
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
AGPS alkylglycerone phosphate synthase
ANXA2P1 annexin A2 pseudogene 1
ARRB1 arrestin, beta 1
ASGR2 asialoglycoprotein receptor 2
ATXN2 ataxin 2
BEAN1 brain expressed, associated with NEDD4, 1
BHMT betaine--homocysteine S-methyltransferase
BIRC7 baculoviral IAP repeat containing 7
C16ORF59 chromosome 16 open reading frame 59
C19ORF24 chromosome 19 open reading frame 24
C1ORF105 chromosome 1 open reading frame 105
C5 complement component 5
CCDC94 coiled-coil domain containing 94
CCR8 chemokine (C-C motif) receptor 8
CD1A CD1a molecule
CDH22 cadherin 22, type 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHGB chromogranin B
CNPY3 canopy FGF signaling regulator 3
COL6A3 collagen, type VI, alpha 3
CORO7 coronin 7
CORT cortistatin
CXORF21 chromosome X open reading frame 21
CYB5R2 cytochrome b5 reductase 2
DET1 de-etiolated homolog 1 (Arabidopsis)
EGR2 early growth response 2
ELP6 elongator acetyltransferase complex subunit 6
FLCN folliculin
FSCN3 fascin actin-bundling protein 3, testicular
FSHB follicle stimulating hormone, beta polypeptide
FUZ fuzzy planar cell polarity protein
GLDC glycine dehydrogenase (decarboxylating)
GMEB1 glucocorticoid modulatory element binding protein 1
GPC3 glypican 3
GPR176 G protein-coupled receptor 176
HIST1H4J histone cluster 1, H4j
HPGDS hematopoietic prostaglandin D synthase
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL15RA interleukin 15 receptor, alpha
IQCG IQ motif containing G
IRS4 insulin receptor substrate 4
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL3 kelch-like family member 3
KRT32 keratin 32, type I
KRT85 keratin 85, type II
LEMD3 LEM domain containing 3
LGALS13 lectin, galactoside-binding, soluble, 13
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
MAML3 mastermind-like 3 (Drosophila)
MARC1 mitochondrial amidoxime reducing component 1
MBNL3 muscleblind-like splicing regulator 3
MCOLN3 mucolipin 3
MMP7 matrix metallopeptidase 7
MTMR10 myotubularin related protein 10
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NCALD neurocalcin delta
NEUROD6 neuronal differentiation 6
OPRK1 opioid receptor, kappa 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR5I1 olfactory receptor, family 5, subfamily I, member 1
PDE8B phosphodiesterase 8B
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIPOX pipecolic acid oxidase
PSAT1 phosphoserine aminotransferase 1
PVRIG poliovirus receptor related immunoglobulin domain containing
RBP1 retinol binding protein 1, cellular
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
S1PR4 sphingosine-1-phosphate receptor 4
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SH2D2A SH2 domain containing 2A
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNX15 sorting nexin 15
SOX21 SRY (sex determining region Y)-box 21
SPP2 secreted phosphoprotein 2, 24kDa
SUN2 Sad1 and UNC84 domain containing 2
SUSD4 sushi domain containing 4
TCHH trichohyalin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM187 transmembrane protein 187
TMEM39A transmembrane protein 39A
TMSB4Y thymosin beta 4, Y-linked
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZNF184 zinc finger protein 184
ZNF74 zinc finger protein 74
ZNF787 zinc finger protein 787