apoptotic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

832 genes co-occuring with the biological term apoptotic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABALON apoptotic BCL2L1-antisense long non-coding RNA
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRB1 adhesion G protein-coupled receptor B1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
AES amino-terminal enhancer of split
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGER advanced glycosylation end product-specific receptor
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGPS alkylglycerone phosphate synthase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AIP aryl hydrocarbon receptor interacting protein
AIRE autoimmune regulator
AK2 adenylate kinase 2
AKAP8 A kinase (PRKA) anchor protein 8
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
ALKBH7 alkB, alkylation repair homolog 7 (E. coli)
ALOX5 arachidonate 5-lipoxygenase
AMBRA1 autophagy/beclin-1 regulator 1
ANO1 anoctamin 1, calcium activated chloride channel
ANXA1 annexin A1
ANXA2 annexin A2
ANXA4 annexin A4
ANXA5 annexin A5
APAF1 apoptotic peptidase activating factor 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC adenomatous polyposis coli
APCS amyloid P component, serum
APIP APAF1 interacting protein
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARF4 ADP-ribosylation factor 4
ARRB2 arrestin, beta 2
ATG12 autophagy related 12
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG5 autophagy related 5
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP13A2 ATPase type 13A2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATR ATR serine/threonine kinase
ATXN2 ataxin 2
ATXN3 ataxin 3
AURKA aurora kinase A
AURKB aurora kinase B
AVEN apoptosis, caspase activation inhibitor
AXL AXL receptor tyrosine kinase
B3GAT1 beta-1,3-glucuronyltransferase 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAD BCL2-associated agonist of cell death
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCLAF1 BCL2-associated transcription factor 1
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BHLHE40 basic helix-loop-helix family, member e40
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BMF Bcl2 modifying factor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMX BMX non-receptor tyrosine kinase
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C11ORF31 chromosome 11 open reading frame 31
C1QA complement component 1, q subcomponent, A chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C22ORF29 chromosome 22 open reading frame 29
C3 complement component 3
C4B complement component 4B (Chido blood group)
C4BPB complement component 4 binding protein, beta
CA8 carbonic anhydrase VIII
CABLES2 Cdk5 and Abl enzyme substrate 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALHM1 calcium homeostasis modulator 1
CALR calreticulin
CAMLG calcium modulating ligand
CANX calnexin
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CCNB1 cyclin B1
CCND1 cyclin D1
CCNT1 cyclin T1
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD209 CD209 molecule
CD27 CD27 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD37 CD37 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CD69 CD69 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD9 CD9 molecule
CD93 CD93 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDC7 cell division cycle 7
CDCA7L cell division cycle associated 7-like
CDIP1 cell death-inducing p53 target 1
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CELF2 CUGBP, Elav-like family member 2
CFH complement factor H
CFLAR CASP8 and FADD-like apoptosis regulator
CFP complement factor properdin
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHMP5 charged multivesicular body protein 5
CHRM3 cholinergic receptor, muscarinic 3
CHUK conserved helix-loop-helix ubiquitous kinase
CLIC4 chloride intracellular channel 4
CLSPN claspin
CMA1 chymase 1, mast cell
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COX2
COX6C cytochrome c oxidase subunit VIc
COX7B cytochrome c oxidase subunit VIIb
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB1 cAMP responsive element binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CRLS1 cardiolipin synthase 1
CRP C-reactive protein, pentraxin-related
CSN3 casein kappa
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSD cathepsin D
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYCS cytochrome c, somatic
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2IP DAB2 interacting protein
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DCLK1 doublecortin-like kinase 1
DCT dopachrome tautomerase
DDIT3 DNA-damage-inducible transcript 3
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DEGS1 delta(4)-desaturase, sphingolipid 1
DESI2 desumoylating isopeptidase 2
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHCR24 24-dehydrocholesterol reductase
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DIABLO diablo, IAP-binding mitochondrial protein
DKK2 dickkopf WNT signaling pathway inhibitor 2
DLAT dihydrolipoamide S-acetyltransferase
DNASE1L3 deoxyribonuclease I-like 3
DNM1L dynamin 1-like
E2F1 E2F transcription factor 1
EBAG9 estrogen receptor binding site associated, antigen, 9
EBI3 Epstein-Barr virus induced 3
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF5A eukaryotic translation initiation factor 5A
ELAVL1 ELAV like RNA binding protein 1
ELMO1 engulfment and cell motility 1
EMD emerin
ENDOG endonuclease G
ENO1 enolase 1, (alpha)
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPHA1 EPH receptor A1
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAIM Fas apoptotic inhibitory molecule
FAM162A family with sequence similarity 162, member A
FAM3B family with sequence similarity 3, member B
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCAR Fc fragment of IgA receptor
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCMR Fc fragment of IgM receptor
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FERMT3 fermitin family member 3
FGF7 fibroblast growth factor 7
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLCN folliculin
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT1 fms-related tyrosine kinase 1
FOXL2 forkhead box L2
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAP GABA(A) receptor-associated protein
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GAK cyclin G associated kinase
GALC galactosylceramidase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCG glucagon
GDF15 growth differentiation factor 15
GFER growth factor, augmenter of liver regeneration
GGT1 gamma-glutamyltransferase 1
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GKN1 gastrokine 1
GLO1 glyoxalase I
GNLY granulysin
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPSM1 G-protein signaling modulator 1
GPX2 glutathione peroxidase 2
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AFX H2A histone family, member X
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HAX1 HCLS1 associated protein X-1
HCST hematopoietic cell signal transducer
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC9 histone deacetylase 9
HDGF hepatoma-derived growth factor
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIP1 huntingtin interacting protein 1
HIPK2 homeodomain interacting protein kinase 2
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST2H3C histone cluster 2, H3c
HIST3H3 histone cluster 3, H3
HK1 hexokinase 1
HK2 hexokinase 2
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOMER1 homer scaffolding protein 1
HOXA5 homeobox A5
HOXA@ homeobox A cluster
HOXD@ homeobox D cluster
HRAS Harvey rat sarcoma viral oncogene homolog
HRG histidine-rich glycoprotein
HRK harakiri, BCL2 interacting protein
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AA2P heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTRA2 HtrA serine peptidase 2
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IER3 immediate early response 3
IFNG interferon, gamma
IFT57 intraflagellar transport 57
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL21R interleukin 21 receptor
IL24 interleukin 24
IL27 interleukin 27
IL33 interleukin 33
IL6 interleukin 6
IL7 interleukin 7
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
ING4 inhibitor of growth family, member 4
IP6K2 inositol hexakisphosphate kinase 2
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KIF1B kinesin family member 1B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KMT2B lysine (K)-specific methyltransferase 2B
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
LALBA lactalbumin, alpha-
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LATS1 large tumor suppressor kinase 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LMNA lamin A/C
LMNB1 lamin B1
LOXL2 lysyl oxidase-like 2
LRG1 leucine-rich alpha-2-glycoprotein 1
LRP1 low density lipoprotein receptor-related protein 1
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MADD MAP-kinase activating death domain
MAN2C1 mannosidase, alpha, class 2C, member 1
MAOA monoamine oxidase A
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MFN2 mitofusin 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR106A microRNA 106a
MIR125B1 microRNA 125b-1
MIR145 microRNA 145
MIR221 microRNA 221
MIR222 microRNA 222
MIR223 microRNA 223
MIR24-2 microRNA 24-2
MIR30D microRNA 30d
MIR34A microRNA 34a
MIR34B microRNA 34b
MIR34C microRNA 34c
MIRLET7A1 microRNA let-7a-1
MIRLET7C microRNA let-7c
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOAP1 modulator of apoptosis 1
MOB4 MOB family member 4, phocein
MPO myeloperoxidase
MPV17 MpV17 mitochondrial inner membrane protein
MSN moesin
MST1 macrophage stimulating 1
MSX1 msh homeobox 1
MSX2 msh homeobox 2
MTCH2 mitochondrial carrier 2
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NACA nascent polypeptide-associated complex alpha subunit
NBN nibrin
NCL nucleolin
NCOR1 nuclear receptor corepressor 1
NDRG2 NDRG family member 2
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGF nerve growth factor (beta polypeptide)
NLRP10 NLR family, pyrin domain containing 10
NLRP12 NLR family, pyrin domain containing 12
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
NLRP7 NLR family, pyrin domain containing 7
NME4 NME/NM23 nucleoside diphosphate kinase 4
NOG noggin
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPTX1 neuronal pentraxin I
NPTX2 neuronal pentraxin II
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUMA1 nuclear mitotic apparatus protein 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA1 optic atrophy 1 (autosomal dominant)
OPRK1 opioid receptor, kappa 1
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PA2G4 proliferation-associated 2G4, 38kDa
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PABPC5 poly(A) binding protein, cytoplasmic 5
PABPN1 poly(A) binding protein, nuclear 1
PACS2 phosphofurin acidic cluster sorting protein 2
PADI2 peptidyl arginine deiminase, type II
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PAWR PRKC, apoptosis, WT1, regulator
PAX2 paired box 2
PAX6 paired box 6
PBX1 pre-B-cell leukemia homeobox 1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDCD5 programmed cell death 5
PDCD6 programmed cell death 6
PDCD6IP programmed cell death 6 interacting protein
PDIA2 protein disulfide isomerase family A, member 2
PEBP1 phosphatidylethanolamine binding protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PER1 period circadian clock 1
PER3 period circadian clock 3
PERP PERP, TP53 apoptosis effector
PFN1 profilin 1
PHB prohibitin
PHGDH phosphoglycerate dehydrogenase
PIAS3 protein inhibitor of activated STAT, 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITX1 paired-like homeodomain 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAUR plasminogen activator, urokinase receptor
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLG plasminogen
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
POU1F1 POU class 1 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPID peptidylprolyl isomerase D
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP5C protein phosphatase 5, catalytic subunit
PRDM1 PR domain containing 1, with ZNF domain
PRDX3 peroxiredoxin 3
PRF1 perforin 1 (pore forming protein)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRNP prion protein
PRODH2 proline dehydrogenase (oxidase) 2
PROS1 protein S (alpha)
PRPF4B pre-mRNA processing factor 4B
PRTN3 proteinase 3
PSENEN presenilin enhancer gamma secretase subunit
PSIP1 PC4 and SFRS1 interacting protein 1
PSRC1 proline/serine-rich coiled-coil 1
PTAFR platelet-activating factor receptor
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTMA prothymosin, alpha
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRH protein tyrosine phosphatase, receptor type, H
PTRH2 peptidyl-tRNA hydrolase 2
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD21 RAD21 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RANBP9 RAN binding protein 9
RARA retinoic acid receptor, alpha
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RB1 retinoblastoma 1
RBM10 RNA binding motif protein 10
RBM5 RNA binding motif protein 5
RBP1 retinol binding protein 1, cellular
RCAN1 regulator of calcineurin 1
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELL1 RELT-like 1
RELL2 RELT-like 2
RELT RELT tumor necrosis factor receptor
RFK riboflavin kinase
RGN regucalcin
RHBDD1 rhomboid domain containing 1
RHBDD3 rhomboid domain containing 3
RHEB Ras homolog enriched in brain
RHOA ras homolog family member A
RHOBTB2 Rho-related BTB domain containing 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RMDN3 regulator of microtubule dynamics 3
RNF144A ring finger protein 144A
RNF186 ring finger protein 186
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROMO1 reactive oxygen species modulator 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RTN1 reticulon 1
RTN3 reticulon 3
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
RYR2 ryanodine receptor 2 (cardiac)
S100B S100 calcium binding protein B
SCARB1 scavenger receptor class B, member 1
SCN3B sodium channel, voltage gated, type III beta subunit
SDC2 syndecan 2
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFTPA1 surfactant protein A1
SFTPC surfactant protein C
SFTPD surfactant protein D
SGMS1 sphingomyelin synthase 1
SH2D1A SH2 domain containing 1A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPA signal-regulatory protein alpha
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SIVA1 SIVA1, apoptosis-inducing factor
SKI SKI proto-oncogene
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLPI secretory leukocyte peptidase inhibitor
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPN sialophorin
SPTA1 spectrin, alpha, erythrocytic 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSB Sjogren syndrome antigen B (autoantigen La)
SSH2 slingshot protein phosphatase 2
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAB1 stabilin 1
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STK3 serine/threonine kinase 3
STK39 serine threonine kinase 39
STK4 serine/threonine kinase 4
STX4 syntaxin 4
SULF1 sulfatase 1
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN transgelin
TAL1 T-cell acute lymphocytic leukemia 1
TAOK1 TAO kinase 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THEMIS2 thymocyte selection associated family member 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TP53BP2 tumor protein p53 binding protein 2
TP53I11 tumor protein p53 inducible protein 11
TP63 tumor protein p63
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TPX2 TPX2, microtubule-associated
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRIB3 tribbles pseudokinase 3
TRIM21 tripartite motif containing 21
TROVE2 TROVE domain family, member 2
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRRAP transformation/transcription domain-associated protein
TSPO translocator protein (18kDa)
TSPY1 testis specific protein, Y-linked 1
TULP1 tubby like protein 1
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein
TYMP thymidine phosphorylase
TYRO3 TYRO3 protein tyrosine kinase
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2N ubiquitin-conjugating enzyme E2N
UBXN2A UBX domain protein 2A
UGT8 UDP glycosyltransferase 8
UNC5D unc-5 homolog D (C. elegans)
USO1 USO1 vesicle transport factor
USP18 ubiquitin specific peptidase 18
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
UTRN utrophin
UVRAG UV radiation resistance associated
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VEGFA vascular endothelial growth factor A
VGLL4 vestigial-like family member 4
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VIPR2 vasoactive intestinal peptide receptor 2
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VWF von Willebrand factor
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT3 wingless-type MMTV integration site family, member 3
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XKR8 XK, Kell blood group complex subunit-related family, member 8
XPA xeroderma pigmentosum, complementation group A
YAP1 Yes-associated protein 1
ZBTB7A zinc finger and BTB domain containing 7A