aplastic anemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow. (Human Disease Ontology, DOID_12449)
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Genes

553 genes co-occuring with the disease aplastic anemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FANCD2 Fanconi anemia, complementation group D2 3.02546
FANCA Fanconi anemia, complementation group A 2.85446
FANCC Fanconi anemia, complementation group C 2.66686
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 2.55559
FANCI Fanconi anemia, complementation group I 2.31742
BRIP1 BRCA1 interacting protein C-terminal helicase 1 2.24948
FANCM Fanconi anemia, complementation group M 2.24736
RPS19 ribosomal protein S19 2.22072
ALAS2 5'-aminolevulinate synthase 2 2.1608
FANCF Fanconi anemia, complementation group F 2.10567
FANCL Fanconi anemia, complementation group L 1.95864
FANCE Fanconi anemia, complementation group E 1.93045
BRCA2 breast cancer 2, early onset 1.88713
EPO erythropoietin 1.85866
FANCG Fanconi anemia, complementation group G 1.85228
RPL11 ribosomal protein L11 1.84636
RAD51 RAD51 recombinase 1.83364
RPS17 ribosomal protein S17 1.83047
SAA1 serum amyloid A1 1.81239
SLX4 SLX4 structure-specific endonuclease subunit 1.79075
RPS24 ribosomal protein S24 1.77586
RPL35A ribosomal protein L35a 1.76094
RPL5 ribosomal protein L5 1.7396
C19ORF40 chromosome 19 open reading frame 40 1.72183
PALB2 partner and localizer of BRCA2 1.71909
BRCA1 breast cancer 1, early onset 1.70679
FAN1 FANCD2/FANCI-associated nuclease 1 1.69996
CD34 CD34 molecule 1.69405
IL3 interleukin 3 1.65745
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1.62425
USP1 ubiquitin specific peptidase 1 1.572
ALAS1 5'-aminolevulinate synthase 1 1.572
THPO thrombopoietin 1.54142
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.51984
RAD51C RAD51 paralog C 1.5194
HLA-C major histocompatibility complex, class I, C 1.51325
UBE2T ubiquitin-conjugating enzyme E2T 1.49438
RPS26 ribosomal protein S26 1.49438
CD59 CD59 molecule, complement regulatory protein 1.4856
RAD18 RAD18 E3 ubiquitin protein ligase 1.48165
PUS1 pseudouridylate synthase 1 1.47462
ERCC4 excision repair cross-complementation group 4 1.45045
WDR48 WD repeat domain 48 1.44035
STRA13 stimulated by retinoic acid 13 1.43639
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.40089
SLC25A38 solute carrier family 25, member 38 1.37425
MUS81 MUS81 structure-specific endonuclease subunit 1.35986
RPS14 ribosomal protein S14 1.32541
GLRX5 glutaredoxin 5 1.31624
FANCB Fanconi anemia, complementation group B 1.30707
C17ORF70 chromosome 17 open reading frame 70 1.29877
RPS10 ribosomal protein S10 1.27693
HLA-A major histocompatibility complex, class I, A 1.22952
RPL26L1 ribosomal protein L26-like 1 1.20829
RPL26 ribosomal protein L26 1.20353
DKC1 dyskeratosis congenita 1, dyskerin 1.2018
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.18324
ATM ATM serine/threonine kinase 1.17507
DDX11L8 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 8 1.16521
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.16521
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.16521
SBDS Shwachman-Bodian-Diamond syndrome 1.1439
CHEK1 checkpoint kinase 1 1.14136
DCLRE1A DNA cross-link repair 1A 1.13712
FTL ferritin, light polypeptide 1.13585
FTH1 ferritin, heavy polypeptide 1 1.13543
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 1.10594
CD4 CD4 molecule 1.08957
APITD1 apoptosis-inducing, TAF9-like domain 1 1.05471
RARS arginyl-tRNA synthetase 1.04798
RPS16 ribosomal protein S16 1.04504
TP53 tumor protein p53 1.01765
H2AFX H2A histone family, member X 0.988535
TERT telomerase reverse transcriptase 0.986428
MPL MPL proto-oncogene, thrombopoietin receptor 0.976744
SFXN2 sideroflexin 2 0.974642
RPS26P6 ribosomal protein S26 pseudogene 6 0.954525
RAD50 RAD50 homolog (S. cerevisiae) 0.947435
NOP10 NOP10 ribonucleoprotein 0.946603
ATRIP ATR interacting protein 0.943274
FECH ferrochelatase 0.922974
RPL7P32 ribosomal protein L7 pseudogene 32 0.916787
GGNBP1 gametogenetin binding protein 1 (pseudogene) 0.90321
ZBTB32 zinc finger and BTB domain containing 32 0.890898
CD52 CD52 molecule 0.877376
RPS29 ribosomal protein S29 0.876557
TF transferrin 0.872462
TNF tumor necrosis factor 0.870415
CD48 CD48 molecule 0.866731
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.863046
PARK2 parkin RBR E3 ubiquitin protein ligase 0.858134
TBX21 T-box 21 0.858134
CSF3 colony stimulating factor 3 (granulocyte) 0.856905
ERCC1 excision repair cross-complementation group 1 0.851583
BLM Bloom syndrome, RecQ helicase-like 0.832329
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.829869
RPL35 ribosomal protein L35 0.826999
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.822897
TFRC transferrin receptor 0.816745
SH2D1A SH2 domain containing 1A 0.813462
REV1 REV1, polymerase (DNA directed) 0.812232
XPA xeroderma pigmentosum, complementation group A 0.811001
NHP2 NHP2 ribonucleoprotein 0.796642
IL2 interleukin 2 0.790081
USP12 ubiquitin specific peptidase 12 0.787623
RPL36 ribosomal protein L36 0.776977
NAAA N-acylethanolamine acid amidase 0.761047
SNX5 sorting nexin 5 0.760639
USP46 ubiquitin specific peptidase 46 0.751678
INTS7 integrator complex subunit 7 0.751271
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.745985
UBE2H ubiquitin-conjugating enzyme E2H 0.745578
XPC xeroderma pigmentosum, complementation group C 0.739894
RPS28 ribosomal protein S28 0.730571
ZBTB16 zinc finger and BTB domain containing 16 0.719654
RPL7 ribosomal protein L7 0.716425
TOP3A topoisomerase (DNA) III alpha 0.715215
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.715215
RPS25 ribosomal protein S25 0.711587
LIG4 ligase IV, DNA, ATP-dependent 0.709975
WRN Werner syndrome, RecQ helicase-like 0.709572
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.701526
PGK1 phosphoglycerate kinase 1 0.698715
IGHV4-39 immunoglobulin heavy variable 4-39 0.6939
GPR156 G protein-coupled receptor 156 0.687091
RPS15 ribosomal protein S15 0.677504
PCNA proliferating cell nuclear antigen 0.670732
PRF1 perforin 1 (pore forming protein) 0.669936
TOPBP1 topoisomerase (DNA) II binding protein 1 0.656046
GAR1 GAR1 ribonucleoprotein 0.653276
PUS3 pseudouridylate synthase 3 0.648138
CD33 CD33 molecule 0.639857
FASLG Fas ligand (TNF superfamily, member 6) 0.63907
ATAD5 ATPase family, AAA domain containing 5 0.633563
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.633169
SFXN1 sideroflexin 1 0.633169
RPL15 ribosomal protein L15 0.624535
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.623751
YARS tyrosyl-tRNA synthetase 0.614356
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.608885
MLH1 mutL homolog 1 0.606933
POT1 protection of telomeres 1 0.604591
GPR132 G protein-coupled receptor 132 0.60264
B3GAT1 beta-1,3-glucuronyltransferase 1 0.59991
HP haptoglobin 0.596012
RAD51AP1 RAD51 associated protein 1 0.595623
RPLP2 ribosomal protein, large, P2 0.593285
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.589779
HPR haptoglobin-related protein 0.589779
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.589001
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.587444
EPOR erythropoietin receptor 0.584719
RPL36AL ribosomal protein L36a-like 0.581217
KITLG KIT ligand 0.572662
IL11 interleukin 11 0.571107
JPH4 junctophilin 4 0.571107
TELO2 telomere maintenance 2 0.569941
MDC1 mediator of DNA-damage checkpoint 1 0.568775
RIOK2 RIO kinase 2 0.565666
RPL14 ribosomal protein L14 0.55712
ISCU iron-sulfur cluster assembly enzyme 0.555568
EXD2 exonuclease 3'-5' domain containing 2 0.55518
FOXP3 forkhead box P3 0.548583
NKX6-2 NK6 homeobox 2 0.546644
HELQ helicase, POLQ-like 0.54393
GATA2 GATA binding protein 2 0.531154
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.528063
RPS2 ribosomal protein S2 0.523816
GSTA2 glutathione S-transferase alpha 2 0.518805
HFE hemochromatosis 0.516879
SFSWAP splicing factor, suppressor of white-apricot family 0.515725
NCAM1 neural cell adhesion molecule 1 0.514956
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.513802
GSTA1 glutathione S-transferase alpha 1 0.51188
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.511112
KRT83 keratin 83, type II 0.501909
RMI2 RecQ mediated genome instability 2 0.499614
ERCC2 excision repair cross-complementation group 2 0.497321
RECQL RecQ helicase-like 0.496557
RPS3 ribosomal protein S3 0.490072
GSTA3 glutathione S-transferase alpha 3 0.489311
GSTA4 glutathione S-transferase alpha 4 0.486646
SOD2 superoxide dismutase 2, mitochondrial 0.482464
CD38 CD38 molecule 0.482464
MPO myeloperoxidase 0.482084
MCM9 minichromosome maintenance complex component 9 0.480945
PKLR pyruvate kinase, liver and RBC 0.479807
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.479427
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 0.479427
FLT3 fms-related tyrosine kinase 3 0.479427
CCL3 chemokine (C-C motif) ligand 3 0.474877
RPL38 ribosomal protein L38 0.473361
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.471089
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.460129
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.459373
RPS7 ribosomal protein S7 0.457487
RNF144B ring finger protein 144B 0.455601
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.453716
EME1 essential meiotic structure-specific endonuclease 1 0.448064
PARP1 poly (ADP-ribose) polymerase 1 0.446182
ALPPL2 alkaline phosphatase, placental-like 2 0.444676
ALPP alkaline phosphatase, placental 0.4443
ALPL alkaline phosphatase, liver/bone/kidney 0.443547
GGN gametogenetin 0.439034
ERCC8 excision repair cross-complementation group 8 0.438282
JAK2 Janus kinase 2 0.43753
SLC25A40 solute carrier family 25, member 40 0.434524
POLN polymerase (DNA directed) nu 0.434524
GYPA glycophorin A (MNS blood group) 0.434148
CD19 CD19 molecule 0.431894
RPS21 ribosomal protein S21 0.431144
RPL37 ribosomal protein L37 0.429642
IL6 interleukin 6 0.428891
WT1 Wilms tumor 1 0.425139
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 0.421765
PKM pyruvate kinase, muscle 0.414276
NSG1 neuron specific gene family member 1 0.407172
UNC45A unc-45 homolog A (C. elegans) 0.406425
RPL27 ribosomal protein L27 0.404931
RPL23A ribosomal protein L23a 0.403811
TFR2 transferrin receptor 2 0.403438
CHMP1A charged multivesicular body protein 1A 0.401945
IL2RA interleukin 2 receptor, alpha 0.397098
ATG10 autophagy related 10 0.396725
RMI1 RecQ mediated genome instability 1 0.393001
STAT4 signal transducer and activator of transcription 4 0.392257
SCAPER S-phase cyclin A-associated protein in the ER 0.390769
UIMC1 ubiquitin interaction motif containing 1 0.390397
RPL10A ribosomal protein L10a 0.390397
RPL9 ribosomal protein L9 0.388909
ECI2 enoyl-CoA delta isomerase 2 0.387794
GSTTP1 glutathione S-transferase theta pseudogene 1 0.384451
GSTT1 glutathione S-transferase theta 1 0.384079
RAD9A RAD9 homolog A (S. pombe) 0.382966
GATA3 GATA binding protein 3 0.382594
RPL31 ribosomal protein L31 0.379997
RPL21 ribosomal protein L21 0.379256
HAMP hepcidin antimicrobial peptide 0.377773
MSN moesin 0.377402
ALAD aminolevulinate dehydratase 0.37629
TIGIT T cell immunoreceptor with Ig and ITIM domains 0.375179
EXO1 exonuclease 1 0.374438
DNAH8 dynein, axonemal, heavy chain 8 0.374438
AGO2 argonaute RISC catalytic component 2 0.373698
CAT catalase 0.371847
RECQL5 RecQ protein-like 5 0.369997
RPS6 ribosomal protein S6 0.368149
IPO4 importin 4 0.367779
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.361502
RAD52 RAD52 homolog (S. cerevisiae) 0.361133
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.358551
CPOX coproporphyrinogen oxidase 0.357077
SPTA1 spectrin, alpha, erythrocytic 1 0.354868
RAB20 RAB20, member RAS oncogene family 0.352659
G6PD glucose-6-phosphate dehydrogenase 0.35082
DNA2 DNA replication helicase/nuclease 2 0.348246
LIG1 ligase I, DNA, ATP-dependent 0.344207
RPL39 ribosomal protein L39 0.342372
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.339806
NEIL1 nei endonuclease VIII-like 1 (E. coli) 0.33944
STAT1 signal transducer and activator of transcription 1, 91kDa 0.337608
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.334315
SPHAR S-phase response (cyclin related) 0.333583
GGNBP2 gametogenetin binding protein 2 0.326281
RPS15A ribosomal protein S15a 0.325187
RPLP1 ribosomal protein, large, P1 0.324094
EPHA8 EPH receptor A8 0.324094
UBE2N ubiquitin-conjugating enzyme E2N 0.321909
FXN frataxin 0.320817
HFE2 hemochromatosis type 2 (juvenile) 0.316456
ALB albumin 0.315729
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.313915
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.313189
CTBP1 C-terminal binding protein 1 0.312827
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.312464
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 0.311377
GSR glutathione reductase 0.311377
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.311377
PGP phosphoglycolate phosphatase 0.31029
RAD17 RAD17 homolog (S. pombe) 0.309204
ADA adenosine deaminase 0.308118
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.307757
GSTM1 glutathione S-transferase mu 1 0.304864
RPL6 ribosomal protein L6 0.303781
RPS23 ribosomal protein S23 0.301615
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.298371
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.298011
RPL30 ribosomal protein L30 0.295851
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 0.295132
ZFP36L2 ZFP36 ring finger protein-like 2 0.294413
RPL8 ribosomal protein L8 0.292257
KRT84 keratin 84, type II 0.290821
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.290821
USP11 ubiquitin specific peptidase 11 0.290103
NOM1 nucleolar protein with MIF4G domain 1 0.288668
MSH2 mutS homolog 2 0.28831
TXN thioredoxin 0.285802
YIPF4 Yip1 domain family, member 4 0.285444
ETV7 ets variant 7 0.283297
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.283297
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.282225
HBG2 hemoglobin, gamma G 0.278654
IRF1 interferon regulatory factor 1 0.27794
CSDE1 cold shock domain containing E1, RNA-binding 0.276158
RPL27A ribosomal protein L27a 0.275445
ERCC6 excision repair cross-complementation group 6 0.274732
RPL12 ribosomal protein L12 0.273664
IL7R interleukin 7 receptor 0.273308
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.269753
HOXB4 homeobox B4 0.268332
RPS4X ribosomal protein S4, X-linked 0.268332
CD7 CD7 molecule 0.262306
ACTL6A actin-like 6A 0.261599
ERCC5 excision repair cross-complementation group 5 0.261599
CHEK2 checkpoint kinase 2 0.260891
UEVLD UEV and lactate/malate dehyrogenase domains 0.260184
FEN1 flap structure-specific endonuclease 1 0.258417
TOP1 topoisomerase (DNA) I 0.258417
RPS20 ribosomal protein S20 0.257711
USP9X ubiquitin specific peptidase 9, X-linked 0.256652
RPA1 replication protein A1, 70kDa 0.253127
CDK12 cyclin-dependent kinase 12 0.253127
RPS3A ribosomal protein S3A 0.25207
TCF12 transcription factor 12 0.251366
RAD51D RAD51 paralog D 0.248203
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.24715
RPL4 ribosomal protein L4 0.245396
RPS19BP1 ribosomal protein S19 binding protein 1 0.243295
RECQL4 RecQ protein-like 4 0.242245
CD79A CD79a molecule, immunoglobulin-associated alpha 0.238403
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.235964
CYGB cytoglobin 0.227988
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.226262
KLK12 kallikrein-related peptidase 12 0.224196
OTP orthopedia homeobox 0.221793
RPS18 ribosomal protein S18 0.221108
RPS18P12 ribosomal protein S18 pseudogene 12 0.221108
UROD uroporphyrinogen decarboxylase 0.217693
APEH acylaminoacyl-peptide hydrolase 0.217352
IGHJ6 immunoglobulin heavy joining 6 0.216672
IGLV3-10 immunoglobulin lambda variable 3-10 0.212608
NHEJ1 nonhomologous end-joining factor 1 0.208914
AGGF1 angiogenic factor with G patch and FHA domains 1 0.206913
MID1 midline 1 0.205916
FTMT ferritin mitochondrial 0.205585
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 0.204923
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.204263
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.203275
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.201635
CDK10 cyclin-dependent kinase 10 0.200656
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 0.199356
HLA-E major histocompatibility complex, class I, E 0.196779
RPL7A ribosomal protein L7a 0.196139
DCLRE1C DNA cross-link repair 1C 0.195183
RPL29 ribosomal protein L29 0.193285
RPL19 ribosomal protein L19 0.193285
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.192971
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.189244
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.189244
CAND1 cullin-associated and neddylation-dissociated 1 0.189244
TCHH trichohyalin 0.187719
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.187113
RPS4Y1 ribosomal protein S4, Y-linked 1 0.187113
RPL32 ribosomal protein L32 0.186811
PDE4C phosphodiesterase 4C, cAMP-specific 0.18591
CHPF chondroitin polymerizing factor 0.185016
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.183541
F2 coagulation factor II (thrombin) 0.183248
ANXA5 annexin A5 0.182086
HLA-DMB major histocompatibility complex, class II, DM beta 0.17896
TDP2 tyrosyl-DNA phosphodiesterase 2 0.177301
HBB hemoglobin, beta 0.175947
HBA1 hemoglobin, alpha 1 0.175411
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.174093
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.172799
TAL1 T-cell acute lymphocytic leukemia 1 0.171785
ADH6 alcohol dehydrogenase 6 (class V) 0.168381
RPL34 ribosomal protein L34 0.168381
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.167224
HIST3H2BB histone cluster 3, H2bb 0.165435
RUNX1 runt-related transcription factor 1 0.165001
SNHG12 small nucleolar RNA host gene 12 0.164359
HIST2H2BF histone cluster 2, H2bf 0.164359
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.164149
HIST1H2BA histone cluster 1, H2ba 0.163111
HIST1H2BD histone cluster 1, H2bd 0.162908
HIST1H2BH histone cluster 1, H2bh 0.162908
IL1A interleukin 1, alpha 0.162707
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.161912
HBA2 hemoglobin, alpha 2 0.161912
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.161139
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.161139
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.160761
SCAI suppressor of cancer cell invasion 0.160761
ATR ATR serine/threonine kinase 0.160574
ATCAY ataxia, cerebellar, Cayman type 0.160203
DHFR dihydrofolate reductase 0.157929
RPL3 ribosomal protein L3 0.143318
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.142462
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 0.141458
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.141249
TFE3 transcription factor binding to IGHM enhancer 3 0.141135
SORD sorbitol dehydrogenase 0.140929
BPIFA1 BPI fold containing family A, member 1 0.140639
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.140379
RPS27A ribosomal protein S27a 0.140173
GGT1 gamma-glutamyltransferase 1 0.13984
ABAT 4-aminobutyrate aminotransferase 0.139112
UBB ubiquitin B 0.139004
GGT2 gamma-glutamyltransferase 2 0.138951
ENO3 enolase 3 (beta, muscle) 0.138717
UROS uroporphyrinogen III synthase 0.13815
PRMT3 protein arginine methyltransferase 3 0.13731
TDO2 tryptophan 2,3-dioxygenase 0.137241
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.136656
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.136455
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.136352
SEC23B Sec23 homolog B (S. cerevisiae) 0.13618
PANK2 pantothenate kinase 2 0.135791
ZSCAN1 zinc finger and SCAN domain containing 1 0.135736
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.135635
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 0.135601
LDHA lactate dehydrogenase A 0.134349
SACS sacsin molecular chaperone 0.133842
PEX2 peroxisomal biogenesis factor 2 0.133709
MZF1 myeloid zinc finger 1 0.132828
RPLP0 ribosomal protein, large, P0 0.132751
TKT transketolase 0.132375
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.131466
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.130558
HIST1H2BF histone cluster 1, H2bf 0.130548
HIST1H2BC histone cluster 1, H2bc 0.130548
IRAK2 interleukin-1 receptor-associated kinase 2 0.130451
NPTX2 neuronal pentraxin II 0.130383
ACPP acid phosphatase, prostate 0.130373
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.130274
HUS1 HUS1 checkpoint homolog (S. pombe) 0.130094
MIR181C microRNA 181c 0.130054
CLSPN claspin 0.129149
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 0.128929
MAGED2 melanoma antigen family D2 0.128885
RBBP8 retinoblastoma binding protein 8 0.128477
OAZ3 ornithine decarboxylase antizyme 3 0.128453
POLM polymerase (DNA directed), mu 0.128383
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.128125
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.12803
CBX3 chromobox homolog 3 0.127787
BRAP BRCA1 associated protein 0.127763
MSH6 mutS homolog 6 0.127739
SNN stannin 0.127392
PSPH phosphoserine phosphatase 0.126829
MORF4 mortality factor 4 (pseudogene) 0.126671
UNC5A unc-5 homolog A (C. elegans) 0.126591
E2F8 E2F transcription factor 8 0.12598
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.125855
NBN nibrin 0.1258
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.125078
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.124768
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.12463
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.124554
TLR8 toll-like receptor 8 0.123663
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.123074
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.123041
NTHL1 nth endonuclease III-like 1 (E. coli) 0.122603
ARID4A AT rich interactive domain 4A (RBP1-like) 0.122395
DDN dendrin 0.122255
HMOX2 heme oxygenase 2 0.121941
MMP17 matrix metallopeptidase 17 (membrane-inserted) 0.121761
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.121599
VAV1 vav 1 guanine nucleotide exchange factor 0.121292
XPO1 exportin 1 0.120846
BIN3 bridging integrator 3 0.120827
GYPE glycophorin E (MNS blood group) 0.120293
RBM15 RNA binding motif protein 15 0.119726
EP400 E1A binding protein p400 0.119687
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.119587
SFXN4 sideroflexin 4 0.119548
E2F6 E2F transcription factor 6 0.118981
CD28 CD28 molecule 0.118569
MT-ATP8 ATP synthase F0 subunit 8 0.116561
DCT dopachrome tautomerase 0.116539
HAS1 hyaluronan synthase 1 0.115939
KLF1 Kruppel-like factor 1 (erythroid) 0.11573
THEM5 thioesterase superfamily member 5 0.115472
PTF1A pancreas specific transcription factor, 1a 0.115232
ACO2 aconitase 2, mitochondrial 0.114381
MYO5A myosin VA (heavy chain 12, myoxin) 0.112442
ACO1 aconitase 1, soluble 0.111886
STOM stomatin 0.111371
MDH1 malate dehydrogenase 1, NAD (soluble) 0.111072
HRK harakiri, BCL2 interacting protein 0.110905
ASL argininosuccinate lyase 0.110682
CDSN corneodesmosin 0.110403
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.110375
HMBS hydroxymethylbilane synthase 0.110039
E2F5 E2F transcription factor 5, p130-binding 0.109636
ULK1 unc-51 like autophagy activating kinase 1 0.109608
TADA1 transcriptional adaptor 1 0.108559
HEPH hephaestin 0.108412
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.107359
TET2 tet methylcytosine dioxygenase 2 0.106996
C10ORF2 chromosome 10 open reading frame 2 0.106496
NFE2 nuclear factor, erythroid 2 0.104095
RPIA ribose 5-phosphate isomerase A 0.1034
POLG polymerase (DNA directed), gamma 0.102962
GZMM granzyme M (lymphocyte met-ase 1) 0.102693
PIDD1 p53-induced death domain protein 1 0.101458
LARS leucyl-tRNA synthetase 0.101145
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.100368
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.100368
TAT tyrosine aminotransferase 0.099582
CS citrate synthase 0.098124
F8 coagulation factor VIII, procoagulant component 0.09805
ASPA aspartoacylase 0.096857
PREB prolactin regulatory element binding 0.096405
IFNA1 interferon, alpha 1 0.096064
HK1 hexokinase 1 0.096025
UMPS uridine monophosphate synthetase 0.09564
GLRA1 glycine receptor, alpha 1 0.095026
GYPC glycophorin C (Gerbich blood group) 0.093971
TCN2 transcobalamin II 0.093932
NCL nucleolin 0.093421
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.093181
GFM1 G elongation factor, mitochondrial 1 0.092582
CD5 CD5 molecule 0.092144
CD2 CD2 molecule 0.092063
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.091778
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.091656
BAG1 BCL2-associated athanogene 0.091494
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.090965
IL2RG interleukin 2 receptor, gamma 0.090844
APRT adenine phosphoribosyltransferase 0.090392
RHCE Rh blood group, CcEe antigens 0.090226
AHSG alpha-2-HS-glycoprotein 0.08973
HTRA2 HtrA serine peptidase 2 0.088646
CENPE centromere protein E, 312kDa 0.088352
ACVRL1 activin A receptor type II-like 1 0.088352
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.087721
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.087679
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.08755
MSH3 mutS homolog 3 0.08755
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.087508
ZBTB7A zinc finger and BTB domain containing 7A 0.087465
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.087294
FIP1L1 factor interacting with PAPOLA and CPSF1 0.087081
THBD thrombomodulin 0.086868
S100P S100 calcium binding protein P 0.086783
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.08674
TPR translocated promoter region, nuclear basket protein 0.086484
PARP2 poly (ADP-ribose) polymerase 2 0.085622
TFAM transcription factor A, mitochondrial 0.085622
IL20RA interleukin 20 receptor, alpha 0.085578
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.085578