anxiety Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. (Experimental Factor Ontology, EFO_0005230)
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Genes

115 genes co-occuring with the biological term anxiety in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMPH amphiphysin
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ASIC1 acid sensing (proton gated) ion channel 1
AVP arginine vasopressin
BAIAP3 BAI1-associated protein 3
BDNF brain-derived neurotrophic factor
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CCK cholecystokinin
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND2 catenin (cadherin-associated protein), delta 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAO D-amino-acid oxidase
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DEL22Q11.2 Chromosome 22q11.2 deletion syndrome, distal
DGCR6 DiGeorge syndrome critical region gene 6
DGCR6L DiGeorge syndrome critical region gene 6-like
DISC1 disrupted in schizophrenia 1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAAH fatty acid amide hydrolase
FKBP5 FK506 binding protein 5
FMR1 fragile X mental retardation 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL galanin/GMAP prepropeptide
GALR1 galanin receptor 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GDNF glial cell derived neurotrophic factor
GLRA1 glycine receptor, alpha 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM7 glutamate receptor, metabotropic 7
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HSPA4 heat shock 70kDa protein 4
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IL17A interleukin 17A
IL6 interleukin 6
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LRP2 low density lipoprotein receptor-related protein 2
LSAMP limbic system-associated membrane protein
MANEA mannosidase, endo-alpha
MAOA monoamine oxidase A
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MECP2 methyl CpG binding protein 2
NGF nerve growth factor (beta polypeptide)
NPPA natriuretic peptide A
NPS neuropeptide S
NPSR1 neuropeptide S receptor 1
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN1 neurexin 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NTSR1 neurotensin receptor 1 (high affinity)
NUCB2 nucleobindin 2
OR7D4 olfactory receptor, family 7, subfamily D, member 4
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PON1 paraoxonase 1
PRNP prion protein
PSEN1 presenilin 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTH2 parathyroid hormone 2
PTH2R parathyroid hormone 2 receptor
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SGCE sarcoglycan, epsilon
SIRT1 sirtuin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMOX spermine oxidase
SMS spermine synthase
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
STMN1 stathmin 1
TBC1D25 TBC1 domain family, member 25
TMEM132D transmembrane protein 132D
TNF tumor necrosis factor
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TSC2 tuberous sclerosis 2
TSPO translocator protein (18kDa)
WNT4 wingless-type MMTV integration site family, member 4
ZNF804A zinc finger protein 804A