antigen receptor-mediated signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell. (Gene Ontology, GO_0050851)
External Link http://amigo.geneontology.org/amigo/term/GO:0050851
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Genes

118 genes participating in the antigen receptor-mediated signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BLK BLK proto-oncogene, Src family tyrosine kinase
BMX BMX non-receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
BTN3A1 butyrophilin, subfamily 3, member A1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CARD11 caspase recruitment domain family, member 11
CD19 CD19 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CHUK conserved helix-loop-helix ubiquitous kinase
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
ENAH enabled homolog (Drosophila)
FOXP3 forkhead box P3
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GRAP2 GRB2-related adaptor protein 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITK IL2-inducible T-cell kinase
KLHL6 kelch-like family member 6
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIME1 Lck interacting transmembrane adaptor 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MALT1 MALT1 paracaspase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MEF2C myocyte enhancer factor 2C
MNDA myeloid cell nuclear differentiation antigen
NCK1 NCK adaptor protein 1
NCKAP1L NCK-associated protein 1-like
NFAM1 NFAT activating protein with ITAM motif 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PRKCB protein kinase C, beta
PRKCQ protein kinase C, theta
PRKD2 protein kinase D2
PSEN1 presenilin 1
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFTN1 raftlin, lipid raft linker 1
RIPK2 receptor-interacting serine-threonine kinase 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF31 ring finger protein 31
RPS27A ribosomal protein S27a
SH2B2 SH2B adaptor protein 2
SKAP1 src kinase associated phosphoprotein 1
SLA2 Src-like-adaptor 2
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
STK11 serine/threonine kinase 11
STOML2 stomatin (EPB72)-like 2
SYK spleen tyrosine kinase
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TEC tec protein tyrosine kinase
THEMIS thymocyte selection associated
THEMIS2 thymocyte selection associated family member 2
THY1 Thy-1 cell surface antigen
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAT1 T cell receptor associated transmembrane adaptor 1
TXK TXK tyrosine kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
VASP vasodilator-stimulated phosphoprotein
VAV3 vav 3 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa