anemia Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells. (Human Disease Ontology, DOID_2355)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0001903
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Genes

125 genes associated with the anemia phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.49739
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 2.45318
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2.32816
OR51B5 olfactory receptor, family 51, subfamily B, member 5 2.24
HBB hemoglobin, beta 2.09818
TTK TTK protein kinase 1.95232
ERAP1 endoplasmic reticulum aminopeptidase 1 1.93365
UBQLNL ubiquilin-like 1.9161
HBG1 hemoglobin, gamma A 1.87878
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 1.8217
WNK1 WNK lysine deficient protein kinase 1 1.81416
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.80864
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.76179
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 1.74483
PDCD11 programmed cell death 11 1.72005
CALHM2 calcium homeostasis modulator 2 1.72005
SSR1 signal sequence receptor, alpha 1.69419
GEMIN4 gem (nuclear organelle) associated protein 4 1.6889
FAM57A family with sequence similarity 57, member A 1.6889
OR51F1 olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene) 1.67665
EBI3 Epstein-Barr virus induced 3 1.65988
PRCP prolylcarboxypeptidase (angiotensinase C) 1.56207
OR52I2 olfactory receptor, family 52, subfamily I, member 2 1.55293
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.35982
OR51E2 olfactory receptor, family 51, subfamily E, member 2 1.33719
OR51I1 olfactory receptor, family 51, subfamily I, member 1 1.28233
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.25886
RRM1 ribonucleotide reductase M1 1.23829
STIM1 stromal interaction molecule 1 1.22185
OR51B6 olfactory receptor, family 51, subfamily B, member 6 1.19958
PCIF1 PDX1 C-terminal inhibiting factor 1 1.16863
NAP1L4 nucleosome assembly protein 1-like 4 1.16191
CSMD1 CUB and Sushi multiple domains 1 1.13459
HBZ hemoglobin, zeta 1.09783
SYT9 synaptotagmin IX 1.07534
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.942765
CLEC12B C-type lectin domain family 12, member B 0.919744
THRB thyroid hormone receptor, beta 0.882984
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 0.868241
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.848109
DSCAM Down syndrome cell adhesion molecule 0.836232
TMEM233 transmembrane protein 233 0.828053
CNTN4 contactin 4 0.799025
SNX29 sorting nexin 29 0.787244
DRD2 dopamine receptor D2 0.776638
CDH13 cadherin 13 0.773909
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.55033
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.456014
WWOX WW domain containing oxidoreductase 0.427495
OTUD3 OTU deubiquitinase 3 0.402467
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.386258
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 0.378957
ZNF804A zinc finger protein 804A 0.376528
MCC mutated in colorectal cancers 0.376528
CDH9 cadherin 9, type 2 (T1-cadherin) 0.375697
ZBED9 zinc finger, BED-type containing 9 0.369844
PHEX phosphate regulating endopeptidase homolog, X-linked 0.367064
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.36638
PHACTR1 phosphatase and actin regulator 1 0.365484
HYKK hydroxylysine kinase 0.36532
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.364891
CDH26 cadherin 26 0.36337
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.362265
HK2 hexokinase 2 0.361063
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.360941
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.360941
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.359801
NLGN4X neuroligin 4, X-linked 0.358578
MAST2 microtubule associated serine/threonine kinase 2 0.356793
BMPR1A bone morphogenetic protein receptor, type IA 0.356409
MAP2K5 mitogen-activated protein kinase kinase 5 0.356288
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.356178
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.356178
IL17RD interleukin 17 receptor D 0.356178
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.356178
PLXNA4 plexin A4 0.355233
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.355233
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 0.353581
SYCE3 synaptonemal complex central element protein 3 0.353581
PRMT8 protein arginine methyltransferase 8 0.353506
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.352851
PARK2 parkin RBR E3 ubiquitin protein ligase 0.352851
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.352505
FAM53B family with sequence similarity 53, member B 0.351537
SPRED3 sprouty-related, EVH1 domain containing 3 0.351537
NRP1 neuropilin 1 0.351355
PPAP2B phosphatidic acid phosphatase type 2B 0.349131
MED27 mediator complex subunit 27 0.348269
PAX8 paired box 8 0.347654
ASUN asunder spermatogenesis regulator 0.347338
USP43 ubiquitin specific peptidase 43 0.347205
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.34686
STON2 stonin 2 0.345657
MAML2 mastermind-like 2 (Drosophila) 0.345657
RAD51B RAD51 paralog B 0.345544
SVIL supervillin 0.345433
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.343239
RNF220 ring finger protein 220 0.34315
MEIS1 Meis homeobox 1 0.343
JAKMIP1 janus kinase and microtubule interacting protein 1 0.343
MTMR10 myotubularin related protein 10 0.343
KLHL33 kelch-like family member 33 0.34262
HNMT histamine N-methyltransferase 0.342374
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.341496
TSHZ2 teashirt zinc finger homeobox 2 0.340946
STAC SH3 and cysteine rich domain 0.340946
UROC1 urocanate hydratase 1 0.340448
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.3398
C14ORF132 chromosome 14 open reading frame 132 0.339396
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.339211
LOC643542 uncharacterized LOC643542 0.338499
OR13D1 olfactory receptor, family 13, subfamily D, member 1 0.337314
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.336034
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.335862
ACAN aggrecan 0.335862
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.335043
LOC648987 uncharacterized LOC648987 0.334713
ZNF329 zinc finger protein 329 0.334039
RYR2 ryanodine receptor 2 (cardiac) 0.334039
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.333556
OPCML opioid binding protein/cell adhesion molecule-like 0.333245
LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene 0.333092
LINC01587 long intergenic non-protein coding RNA 1587 0.332941
DCLK1 doublecortin-like kinase 1 0.331795
DEPTOR DEP domain containing MTOR-interacting protein 0.329663