androsterone-2650 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the androsterone-2650 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM20 ADAM metallopeptidase domain 20
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
AKAP11 A kinase (PRKA) anchor protein 11
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATXN3 ataxin 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D2 B9 protein domain 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN10 calpain 10
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CCDC64 coiled-coil domain containing 64
CCKAR cholecystokinin A receptor
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL6A1 collagen, type VI, alpha 1
CPNE7 copine VII
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DFNB31 deafness, autosomal recessive 31
DVL3 dishevelled segment polarity protein 3
EHBP1L1 EH domain binding protein 1-like 1
EHD2 EH-domain containing 2
ENO3 enolase 3 (beta, muscle)
ERCC2 excision repair cross-complementation group 2
EVPL envoplakin
EXPH5 exophilin 5
EXTL1 exostosin-like glycosyltransferase 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP8 FK506 binding protein 8, 38kDa
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GFER growth factor, augmenter of liver regeneration
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HCFC1 host cell factor C1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
HPS1 Hermansky-Pudlak syndrome 1
IGL immunoglobulin lambda locus
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ITM2C integral membrane protein 2C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0125 KIAA0125
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTB4R leukotriene B4 receptor
MAPK8 mitogen-activated protein kinase 8
MCTP2 multiple C2 domains, transmembrane 2
MON1B MON1 secretory trafficking family member B
MTCP1 mature T-cell proliferation 1
MTMR8 myotubularin related protein 8
MYF5 myogenic factor 5
MYL5 myosin, light chain 5, regulatory
NCOR2 nuclear receptor corepressor 2
NCR2 natural cytotoxicity triggering receptor 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NLE1 notchless homolog 1 (Drosophila)
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NTF3 neurotrophin 3
ONECUT2 one cut homeobox 2
PCNXL2 pecanex-like 2 (Drosophila)
PDIA2 protein disulfide isomerase family A, member 2
PDLIM4 PDZ and LIM domain 4
PHOX2B paired-like homeobox 2b
PIDD1 p53-induced death domain protein 1
PIGR polymeric immunoglobulin receptor
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRSS50 protease, serine, 50
PTAFR platelet-activating factor receptor
PTGIS prostaglandin I2 (prostacyclin) synthase
PURA purine-rich element binding protein A
RAB3A RAB3A, member RAS oncogene family
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAYSD1 SAYSVFN motif domain containing 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SRP72 signal recognition particle 72kDa
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TBX6 T-box 6
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMEM53 transmembrane protein 53
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRA T cell receptor alpha locus
TRD T cell receptor delta locus
TRIM10 tripartite motif containing 10
TUBA3C tubulin, alpha 3c
WDR61 WD repeat domain 61
ZYX zyxin

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE5 adhesion G protein-coupled receptor E5
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARRB1 arrestin, beta 1
AZI2 5-azacytidine induced 2
BAX BCL2-associated X protein
BCORL1 BCL6 corepressor-like 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF46 chromosome 22 open reading frame 46
C5AR2 complement component 5a receptor 2
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD79B CD79b molecule, immunoglobulin-associated beta
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COMMD10 COMM domain containing 10
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP13 dual specificity phosphatase 13
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC4 excision repair cross-complementation group 4
F8 coagulation factor VIII, procoagulant component
FMOD fibromodulin
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HLA-J major histocompatibility complex, class I, J (pseudogene)
IDI2-AS1 IDI2 antisense RNA 1
IER3IP1 immediate early response 3 interacting protein 1
KIAA0895 KIAA0895
KIZ kizuna centrosomal protein
KLHL25 kelch-like family member 25
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LRRC49 leucine rich repeat containing 49
LY6G6C lymphocyte antigen 6 complex, locus G6C
MANEA mannosidase, endo-alpha
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MFSD11 major facilitator superfamily domain containing 11
MORC3 MORC family CW-type zinc finger 3
MXD3 MAX dimerization protein 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PCDHB3 protocadherin beta 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEX26 peroxisomal biogenesis factor 26
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPAP2C phosphatidic acid phosphatase type 2C
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTCD2 pentatricopeptide repeat domain 2
PYGB phosphorylase, glycogen; brain
SCML1 sex comb on midleg-like 1 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A44 solute carrier family 25, member 44
SLC35A5 solute carrier family 35, member A5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNUPN snurportin 1
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TMPRSS3 transmembrane protease, serine 3
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UEVLD UEV and lactate/malate dehyrogenase domains
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
ZFP30 ZFP30 zinc finger protein
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652
ZNF816 zinc finger protein 816