anaplastic large cell lymphoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A non-Hodgkin lymphoma involving aberrant T-cells. (Human Disease Ontology, DOID_0050744)
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Genes

190 genes co-occuring with the disease anaplastic large cell lymphoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALK anaplastic lymphoma receptor tyrosine kinase 3.63425
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 2.3138
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.87699
FGF19 fibroblast growth factor 19 1.82187
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.61575
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.59653
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.48077
PAX5 paired box 5 1.4022
TPM3 tropomyosin 3 1.36248
TPM4 tropomyosin 4 1.30008
NCAM1 neural cell adhesion molecule 1 1.24254
JUNB jun B proto-oncogene 1.23386
PTPRC protein tyrosine phosphatase, receptor type, C 1.18971
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 1.16221
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.14645
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 1.13078
PAX2 paired box 2 1.09755
EML4 echinoderm microtubule associated protein like 4 1.0484
TFG TRK-fused gene 1.0265
CD5 CD5 molecule 1.02608
CD4 CD4 molecule 1.02313
TRAF1 TNF receptor-associated factor 1 1.00879
RNF213 ring finger protein 213 1.00372
CLTC clathrin, heavy chain (Hc) 0.992752
BCL6 B-cell CLL/lymphoma 6 0.991487
MTX3 metaxin 3 0.979689
DUSP22 dual specificity phosphatase 22 0.973801
C14ORF93 chromosome 14 open reading frame 93 0.9717
ZBTB44 zinc finger and BTB domain containing 44 0.9717
PRF1 perforin 1 (pore forming protein) 0.938704
JAK3 Janus kinase 3 0.935799
MLF1 myeloid leukemia factor 1 0.923387
CCND3 cyclin D3 0.916787
CD68 CD68 molecule 0.915139
MIR3187 microRNA 3187 0.914315
CD7 CD7 molecule 0.894179
FSCN1 fascin actin-bundling protein 1 0.870006
FSCN3 fascin actin-bundling protein 3, testicular 0.859771
IRF4 interferon regulatory factor 4 0.849126
PDLIM7 PDZ and LIM domain 7 (enigma) 0.849126
GPR15 G protein-coupled receptor 15 0.846259
HYLS1 hydrolethalus syndrome 1 0.846259
FSCN2 fascin actin-bundling protein 2, retinal 0.831099
CXCR3 chemokine (C-X-C motif) receptor 3 0.829459
MTX1 metaxin 1 0.817155
CDKL3 cyclin-dependent kinase-like 3 0.767985
BCL3 B-cell CLL/lymphoma 3 0.759824
CEP250 centrosomal protein 250kDa 0.735433
CSNK1G3 casein kinase 1, gamma 3 0.714005
CCND2 cyclin D2 0.691094
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.686291
TP53 tumor protein p53 0.671527
IRF6 interferon regulatory factor 6 0.660008
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.618268
IGH immunoglobulin heavy locus 0.614356
ITK IL2-inducible T-cell kinase 0.60186
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.582773
BRI3 brain protein I3 0.580828
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.571107
SKAP1 src kinase associated phosphoprotein 1 0.558285
TARP TCR gamma alternate reading frame protein 0.552075
BCL10 B-cell CLL/lymphoma 10 0.548583
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.545868
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 0.53928
CD79A CD79a molecule, immunoglobulin-associated alpha 0.538118
LEF1 lymphoid enhancer-binding factor 1 0.531541
BCL2L1 BCL2-like 1 0.52729
MSN moesin 0.521117
MUM1 melanoma associated antigen (mutated) 1 0.51842
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.518034
IL22RA1 interleukin 22 receptor, alpha 1 0.509576
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.500379
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.500379
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.498467
MET MET proto-oncogene, receptor tyrosine kinase 0.489311
BIRC5 baculoviral IAP repeat containing 5 0.479047
PPID peptidylprolyl isomerase D 0.467306
JUN jun proto-oncogene 0.466172
TEK TEK tyrosine kinase, endothelial 0.465038
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.46466
GLIS2 GLIS family zinc finger 2 0.463527
CCL17 chemokine (C-C motif) ligand 17 0.458241
LEMD1 LEM domain containing 1 0.453716
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.452585
ZC3HC1 zinc finger, C3HC-type containing 1 0.450701
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.433772
TUBB2B tubulin, beta 2B class IIb 0.432646
POU2F2 POU class 2 homeobox 2 0.431519
IL22 interleukin 22 0.42814
FADD Fas (TNFRSF6)-associated via death domain 0.425139
HOXA3 homeobox A3 0.408292
CCND1 cyclin D1 0.407172
CYTH1 cytohesin 1 0.399334
LTK leukocyte receptor tyrosine kinase 0.398589
CD274 CD274 molecule 0.39598
LCK LCK proto-oncogene, Src family tyrosine kinase 0.394118
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.388166
CD19 CD19 molecule 0.381852
CCNK cyclin K 0.380739
BCL2 B-cell CLL/lymphoma 2 0.367779
PCTP phosphatidylcholine transfer protein 0.365562
BOK BCL2-related ovarian killer 0.363716
RANGAP1 Ran GTPase activating protein 1 0.360764
TCL1A T-cell leukemia/lymphoma 1A 0.360395
RPS6 ribosomal protein S6 0.355604
LGALS3 lectin, galactoside-binding, soluble, 3 0.354868
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.353395
RNASET2 ribonuclease T2 0.353395
DDX11L8 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 8 0.353395
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.34384
LGALS1 lectin, galactoside-binding, soluble, 1 0.338707
CCR3 chemokine (C-C motif) receptor 3 0.338707
ITSN1 intersectin 1 (SH3 domain protein) 0.331391
PRKCQ protein kinase C, theta 0.32701
G0S2 G0/G1 switch 2 0.324094
CD96 CD96 molecule 0.311739
EBP emopamil binding protein (sterol isomerase) 0.311739
INSR insulin receptor 0.308842
DDB1 damage-specific DNA binding protein 1, 127kDa 0.300173
CD22 CD22 molecule 0.296571
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.290103
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.289027
PTPRB protein tyrosine phosphatase, receptor type, B 0.288668
XCL1 chemokine (C motif) ligand 1 0.28616
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.282582
CXCL13 chemokine (C-X-C motif) ligand 13 0.28151
CSN2 casein beta 0.280082
RALGDS ral guanine nucleotide dissociation stimulator 0.275801
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.275089
HRAS Harvey rat sarcoma viral oncogene homolog 0.267622
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.263368
HECA headcase homolog (Drosophila) 0.26266
POU2AF1 POU class 2 associating factor 1 0.262306
TFRC transferrin receptor 0.260538
ADGRL4 adhesion G protein-coupled receptor L4 0.259124
CXCL9 chemokine (C-X-C motif) ligand 9 0.257358
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.255946
BMPR1A bone morphogenetic protein receptor, type IA 0.255594
SIN3A SIN3 transcription regulator family member A 0.253479
B3GAT1 beta-1,3-glucuronyltransferase 1 0.252774
TRAF3 TNF receptor-associated factor 3 0.246799
ANXA5 annexin A5 0.246799
CNTFR ciliary neurotrophic factor receptor 0.243645
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.243295
CCNT1 cyclin T1 0.241895
TIMD4 T-cell immunoglobulin and mucin domain containing 4 0.234573
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.234225
CD52 CD52 molecule 0.233878
HOXC6 homeobox C6 0.22454
PEX14 peroxisomal biogenesis factor 14 0.222479
FAS Fas cell surface death receptor 0.222136
BIRC3 baculoviral IAP repeat containing 3 0.22145
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.220424
VAV1 vav 1 guanine nucleotide exchange factor 0.217012
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.215992
CD69 CD69 molecule 0.212945
DNTT DNA nucleotidylexotransferase 0.20658
IL2RA interleukin 2 receptor, alpha 0.205916
BCL9 B-cell CLL/lymphoma 9 0.205254
TBX21 T-box 21 0.205254
DVL3 dishevelled segment polarity protein 3 0.204923
SCGB1D1 secretoglobin, family 1D, member 1 0.203275
PTN pleiotrophin 0.20229
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.199681
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.199033
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.198709
CHEK1 checkpoint kinase 1 0.194548
GLI3 GLI family zinc finger 3 0.192971
SOCS3 suppressor of cytokine signaling 3 0.190786
VAV2 vav 2 guanine nucleotide exchange factor 0.18621
HDAC11 histone deacetylase 11 0.18621
TIMP1 TIMP metallopeptidase inhibitor 1 0.183541
TRAF2 TNF receptor-associated factor 2 0.180367
MALT1 MALT1 paracaspase 0.180367
SUMO1 small ubiquitin-like modifier 1 0.175947
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.175947
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.171535
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.170789
GATA3 GATA binding protein 3 0.169812
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.169571
FASLG Fas ligand (TNF superfamily, member 6) 0.169091
CDC25A cell division cycle 25A 0.168381
S100A9 S100 calcium binding protein A9 0.166319
SYK spleen tyrosine kinase 0.165217
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.165217
TRIB1 tribbles pseudokinase 1 0.163523
CD44 CD44 molecule (Indian blood group) 0.163111
CCR7 chemokine (C-C motif) receptor 7 0.161523
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.161139
MIR27B microRNA 27b 0.159302