amyotrophic lateral sclerosis Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. (Human Disease Ontology, DOID_332)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:332
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Genes

608 genes associated with the disease amyotrophic lateral sclerosis in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
UNC13A unc-13 homolog A (C. elegans) 1.76581
C9ORF72 chromosome 9 open reading frame 72 1.59609
SUSD2 sushi domain containing 2 1.48714
KRT18P55 keratin 18 pseudogene 55 1.42967
KIFAP3 kinesin-associated protein 3 1.39396
MOB3B MOB kinase activator 3B 1.37537
TIAM1 T-cell lymphoma invasion and metastasis 1 1.37327
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 1.33186
KIAA0040 KIAA0040 1.31635
ANKRD29 ankyrin repeat domain 29 1.31635
CENPV centromere protein V 1.26953
SARM1 sterile alpha and TIR motif containing 1 1.26621
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.24194
KIAA0513 KIAA0513 1.24194
STK36 serine/threonine kinase 36 1.23034
NRXN1 neurexin 1 1.22924
SUN3 Sad1 and UNC84 domain containing 3 1.22017
LAMA3 laminin, alpha 3 1.21996
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.20079
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.19386
C7ORF57 chromosome 7 open reading frame 57 1.18343
TRIM27 tripartite motif containing 27 1.17954
IFRD1 interferon-related developmental regulator 1 1.14463
CNTNAP2 contactin associated protein-like 2 1.12663
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.10764
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 1.07599
NXPH1 neurexophilin 1 1.07599
ATXN1 ataxin 1 1.07599
SELL selectin L 1.07599
FMN2 formin 2 1.07599
IFT74 intraflagellar transport 74 1.04872
PTPRF protein tyrosine phosphatase, receptor type, F 1.04846
KDM4A lysine (K)-specific demethylase 4A 1.04846
ZFP64 ZFP64 zinc finger protein 1.04846
CNOT2 CCR4-NOT transcription complex, subunit 2 1.04846
SUSD1 sushi domain containing 1 1.02476
NRXN3 neurexin 3 1.02476
PHC1 polyhomeotic homolog 1 (Drosophila) 1.02453
SHROOM3 shroom family member 3 1.00788
CPNE4 copine IV 1.00407
PCSK5 proprotein convertase subtilisin/kexin type 5 1.00407
HIATL1 hippocampus abundant transcript-like 1 1.00407
FAM149A family with sequence similarity 149, member A 1.00407
CNTN4 contactin 4 1.00407
THSD7A thrombospondin, type I, domain containing 7A 0.989716
MORN2 MORN repeat containing 2 0.986376
SLC39A11 solute carrier family 39, member 11 0.986376
DISC1 disrupted in schizophrenia 1 0.986376
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.986376
NT5C1A 5'-nucleotidase, cytosolic IA 0.986376
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.972446
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.971169
LIPC lipase, hepatic 0.971169
FHDC1 FH2 domain containing 1 0.971169
OPRD1 opioid receptor, delta 1 0.966295
LOC100652824 0.957195
CHAMP1 chromosome alignment maintaining phosphoprotein 1 0.952622
IFI44L interferon-induced protein 44-like 0.950418
CEP44 centrosomal protein 44kDa 0.947208
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 0.947208
PKD1L1 polycystic kidney disease 1 like 1 0.945129
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 0.93456
BTBD11 BTB (POZ) domain containing 11 0.928472
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26 0.928472
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.916706
TMEM132C transmembrane protein 132C 0.905653
PCSK6 proprotein convertase subtilisin/kexin type 6 0.894421
CRHBP corticotropin releasing hormone binding protein 0.887807
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.861951
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 0.861462
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.861462
MGLL monoglyceride lipase 0.859451
TACC2 transforming, acidic coiled-coil containing protein 2 0.850837
TLR10 toll-like receptor 10 0.847035
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.845188
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.844732
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.843377
ALLC allantoicase 0.839855
GPC6 glypican 6 0.838141
DNM1L dynamin 1-like 0.833585
SOX5 SRY (sex determining region Y)-box 5 0.831182
LRPPRC leucine-rich pentatricopeptide repeat containing 0.820324
CD1E CD1e molecule 0.815307
ARSG arylsulfatase G 0.811614
PDE4B phosphodiesterase 4B, cAMP-specific 0.807012
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.804621
LOC100652894 uncharacterized LOC100652894 0.801631
SUGCT succinyl-CoA:glutarate-CoA transferase 0.799531
CDH13 cadherin 13 0.79774
MIS18A MIS18 kinetochore protein A 0.795282
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.792881
DCHS1 dachsous cadherin-related 1 0.787916
TCEA1 transcription elongation factor A (SII), 1 0.784733
ABAT 4-aminobutyrate aminotransferase 0.783487
HABP2 hyaluronan binding protein 2 0.780437
DEPDC5 DEP domain containing 5 0.780437
KLHL29 kelch-like family member 29 0.778945
FAM49A family with sequence similarity 49, member A 0.776314
RNF14 ring finger protein 14 0.776026
MED17 mediator complex subunit 17 0.775452
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.773469
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.772631
IQGAP2 IQ motif containing GTPase activating protein 2 0.769887
OSBP2 oxysterol binding protein 2 0.760971
OPCML opioid binding protein/cell adhesion molecule-like 0.757946
AGBL4 ATP/GTP binding protein-like 4 0.752656
CABIN1 calcineurin binding protein 1 0.751885
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.750866
MAN2A1 mannosidase, alpha, class 2A, member 1 0.749105
POF1B premature ovarian failure, 1B 0.746396
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.739803
NRF1 nuclear respiratory factor 1 0.739348
ZBTB38 zinc finger and BTB domain containing 38 0.738669
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.73192
NKRF NFKB repressing factor 0.727312
TMEM132D transmembrane protein 132D 0.71781
LOC728392 uncharacterized LOC728392 0.714954
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.714752
ADRBK2 adrenergic, beta, receptor kinase 2 0.714351
NAMPT nicotinamide phosphoribosyltransferase 0.712368
FBXO8 F-box protein 8 0.709651
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.704419
PAX7 paired box 7 0.703873
RBMS2 RNA binding motif, single stranded interacting protein 2 0.702075
DSCAM Down syndrome cell adhesion molecule 0.70172
GRIK2 glutamate receptor, ionotropic, kainate 2 0.699446
TEK TEK tyrosine kinase, endothelial 0.698585
ZNF385B zinc finger protein 385B 0.69773
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.69756
TLR1 toll-like receptor 1 0.688149
ERICH5 glutamate-rich 5 0.687223
MGAM maltase-glucoamylase 0.681983
FAM13B family with sequence similarity 13, member B 0.680967
STX17 syntaxin 17 0.679961
EXO1 exonuclease 1 0.679107
MPZL1 myelin protein zero-like 1 0.678682
TMEM91 transmembrane protein 91 0.677979
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.674941
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.674129
CNTN5 contactin 5 0.671598
SGMS1 sphingomyelin synthase 1 0.671598
HCG26 HLA complex group 26 (non-protein coding) 0.671336
GMDS GDP-mannose 4,6-dehydratase 0.667834
MAOB monoamine oxidase B 0.667834
PCNX pecanex homolog (Drosophila) 0.667834
LTBP2 latent transforming growth factor beta binding protein 2 0.666845
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.665868
ZDHHC23 zinc finger, DHHC-type containing 23 0.664902
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.663004
C2CD2 C2 calcium-dependent domain containing 2 0.662072
REPS2 RALBP1 associated Eps domain containing 2 0.662072
SUSD3 sushi domain containing 3 0.662072
ZNF382 zinc finger protein 382 0.66115
IGBP1 immunoglobulin (CD79A) binding protein 1 0.660239
SYTL4 synaptotagmin-like 4 0.660239
RORA RAR-related orphan receptor A 0.659337
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 0.658446
RAB3C RAB3C, member RAS oncogene family 0.657565
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.655831
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.655831
NLGN4X neuroligin 4, X-linked 0.654978
DMD dystrophin 0.653298
GLRA2 glycine receptor, alpha 2 0.651654
RAB9A RAB9A, member RAS oncogene family 0.651654
KLHL4 kelch-like family member 4 0.651654
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.650844
BARD1 BRCA1 associated RING domain 1 0.650844
CCL25 chemokine (C-C motif) ligand 25 0.648464
FGF1 fibroblast growth factor 1 (acidic) 0.648464
TUBB tubulin, beta class I 0.648464
LOC400958 uncharacterized LOC400958 0.648464
ACOT9 acyl-CoA thioesterase 9 0.647686
CAPN9 calpain 9 0.647016
NELL1 NEL-like 1 (chicken) 0.64588
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.64532
KCTD8 potassium channel tetramerization domain containing 8 0.64532
ZNF185 zinc finger protein 185 (LIM domain) 0.64367
VCAN versican 0.64367
IQCJ IQ motif containing J 0.64367
CADM2 cell adhesion molecule 2 0.642594
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.642594
NRK Nik related kinase 0.641537
FER fer (fps/fes related) tyrosine kinase 0.639476
CREB5 cAMP responsive element binding protein 5 0.638472
SSTR5 somatostatin receptor 5 0.637975
CALN1 calneuron 1 0.636511
SLC35F3 solute carrier family 35, member F3 0.636031
FHOD3 formin homology 2 domain containing 3 0.635554
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 0.634612
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.634147
CAPN13 calpain 13 0.634147
TNPO3 transportin 3 0.634147
ZNF839 zinc finger protein 839 0.632771
FRMPD4 FERM and PDZ domain containing 4 0.632771
C21ORF62 chromosome 21 open reading frame 62 0.63232
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.630132
MAGEA10-MAGEA5 MAGEA10-MAGEA5 readthrough 0.628889
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.627673
SSBP3 single stranded DNA binding protein 3 0.627673
ASPH aspartate beta-hydroxylase 0.627673
KLF8 Kruppel-like factor 8 0.627273
KALRN kalirin, RhoGEF kinase 0.627273
TGOLN2 trans-golgi network protein 2 0.62609
BEX5 brain expressed, X-linked 5 0.625701
PDLIM5 PDZ and LIM domain 5 0.624931
GLI2 GLI family zinc finger 2 0.62455
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.624172
THTPA thiamine triphosphatase 0.624172
APOO apolipoprotein O 0.623796
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.623422
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.623051
NHSL1 NHS-like 1 0.622682
AKAP7 A kinase (PRKA) anchor protein 7 0.62159
LINGO2 leucine rich repeat and Ig domain containing 2 0.620873
ATXN7L1 ataxin 7-like 1 0.620873
TBL1X transducin (beta)-like 1X-linked 0.620873
ZNF271P zinc finger protein 271, pseudogene 0.620165
OR8G5 olfactory receptor, family 8, subfamily G, member 5 0.620165
ZNF414 zinc finger protein 414 0.618434
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 0.617756
ALAS2 5'-aminolevulinate synthase 2 0.617086
PASD1 PAS domain containing 1 0.616754
EYA1 EYA transcriptional coactivator and phosphatase 1 0.616754
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.616424
MAPK1 mitogen-activated protein kinase 1 0.616096
FGF13 fibroblast growth factor 13 0.615445
ALK anaplastic lymphoma receptor tyrosine kinase 0.615118
FAM13A family with sequence similarity 13, member A 0.614766
ACYP2 acylphosphatase 2, muscle type 0.614766
FGF12 fibroblast growth factor 12 0.614416
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.614068
COL14A1 collagen, type XIV, alpha 1 0.614068
WDFY3 WD repeat and FYVE domain containing 3 0.613378
STAC SH3 and cysteine rich domain 0.611686
PLXNA2 plexin A2 0.611023
DIAPH2 diaphanous-related formin 2 0.610041
RTN4R reticulon 4 receptor 0.609717
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.609717
PRKX protein kinase, X-linked 0.60781
CCDC3 coiled-coil domain containing 3 0.607498
SLIT3 slit homolog 3 (Drosophila) 0.606879
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.606572
TULP4 tubby like protein 4 0.604762
GLT8D2 glycosyltransferase 8 domain containing 2 0.60417
TTC29 tetratricopeptide repeat domain 29 0.603877
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.603584
MACROD2 MACRO domain containing 2 0.603294
IQGAP1 IQ motif containing GTPase activating protein 1 0.60243
SHROOM4 shroom family member 4 0.602145
AKAP12 A kinase (PRKA) anchor protein 12 0.601861
IGSF1 immunoglobulin superfamily, member 1 0.601298
LRP1B low density lipoprotein receptor-related protein 1B 0.60074
MYH11 myosin, heavy chain 11, smooth muscle 0.600463
ARHGAP8 Rho GTPase activating protein 8 0.600463
SGPP2 sphingosine-1-phosphate phosphatase 2 0.600187
PCDHGB4 protocadherin gamma subfamily B, 4 0.600187
PCDHGA11 protocadherin gamma subfamily A, 11 0.600187
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.599913
UNC13C unc-13 homolog C (C. elegans) 0.59964
TP63 tumor protein p63 0.599097
CENPF centromere protein F, 350/400kDa 0.598248
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.598248
JARID2 jumonji, AT rich interactive domain 2 0.597957
ZNF423 zinc finger protein 423 0.596524
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.596524
LURAP1L leucine rich adaptor protein 1-like 0.594847
GUCY2EP guanylate cyclase 2E, pseudogene 0.594297
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.593752
ANXA5 annexin A5 0.593482
OR1E2 olfactory receptor, family 1, subfamily E, member 2 0.593482
LARGE like-glycosyltransferase 0.593212
GLS2 glutaminase 2 (liver, mitochondrial) 0.593212
EFHC2 EF-hand domain (C-terminal) containing 2 0.592677
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.591358
TMEM200A transmembrane protein 200A 0.590323
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.589811
IL1A interleukin 1, alpha 0.589557
KSR2 kinase suppressor of ras 2 0.589557
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.588801
ZMAT1 zinc finger, matrin-type 1 0.587071
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.586586
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.585865
ZSCAN30 zinc finger and SCAN domain containing 30 0.585627
NALCN sodium leak channel, non selective 0.585152
APP amyloid beta (A4) precursor protein 0.584916
INSR insulin receptor 0.584916
OPRM1 opioid receptor, mu 1 0.583982
MAGEA11 melanoma antigen family A11 0.583751
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.58352
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.583062
BBS9 Bardet-Biedl syndrome 9 0.583062
CAST calpastatin 0.582834
SORBS2 sorbin and SH3 domain containing 2 0.58124
PCDH15 protocadherin-related 15 0.58076
PARK2 parkin RBR E3 ubiquitin protein ligase 0.580521
DPYD dihydropyrimidine dehydrogenase 0.580521
FAM133A family with sequence similarity 133, member A 0.580521
STARD8 StAR-related lipid transfer (START) domain containing 8 0.580283
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.578181
BCL6 B-cell CLL/lymphoma 6 0.577495
TMPRSS13 transmembrane protease, serine 13 0.577041
CSMD1 CUB and Sushi multiple domains 1 0.577041
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.576591
FAM155A family with sequence similarity 155, member A 0.576591
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.576591
DPF3 D4, zinc and double PHD fingers, family 3 0.576591
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.575039
PTCHD1-AS PTCHD1 antisense RNA (head to head) 0.574603
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.574385
KLHL15 kelch-like family member 15 0.574169
GRM7 glutamate receptor, metabotropic 7 0.573738
SNTG2 syntrophin, gamma 2 0.573738
GUCD1 guanylyl cyclase domain containing 1 0.573738
SYTL3 synaptotagmin-like 3 0.573524
LOC100128714 uncharacterized LOC100128714 0.573097
GXYLT2 glucoside xylosyltransferase 2 0.571834
MIR4500HG MIR4500 host gene 0.571418
SEPT6 septin 6 0.571211
LOC100506272 uncharacterized LOC100506272 0.571005
KDM5A lysine (K)-specific demethylase 5A 0.571005
BNC2 basonuclin 2 0.571005
KDM4B lysine (K)-specific demethylase 4B 0.570187
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.569984
EVC2 Ellis van Creveld syndrome 2 0.569984
BTBD16 BTB (POZ) domain containing 16 0.569782
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.569379
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.568979
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.568979
STAG2 stromal antigen 2 0.56878
DTNA dystrobrevin, alpha 0.56878
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.568581
CC2D2A coiled-coil and C2 domain containing 2A 0.567598
FAM126A family with sequence similarity 126, member A 0.567598
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.567403
SLC38A1 solute carrier family 38, member 1 0.566821
CXORF58 chromosome X open reading frame 58 0.565864
LOC100507662 uncharacterized LOC100507662 0.565485
SEZ6L seizure related 6 homolog (mouse)-like 0.565109
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 0.565109
APOOL apolipoprotein O-like 0.564177
T T, brachyury homolog (mouse) 0.563992
LOC285692 uncharacterized LOC285692 0.563808
IL36B interleukin 36, beta 0.563808
GRM3 glutamate receptor, metabotropic 3 0.563237
GLIS3 GLIS family zinc finger 3 0.562845
NEO1 neogenin 1 0.56265
OSBPL1A oxysterol binding protein-like 1A 0.56265
MXRA5 matrix-remodelling associated 5 0.56265
TVP23C-CDRT4 TVP23C-CDRT4 readthrough 0.561875
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.561682
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.561299
RTFDC1 replication termination factor 2 domain containing 1 0.560918
MYO1D myosin ID 0.559788
KCNIP4 Kv channel interacting protein 4 0.559415
TVP23C trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) 0.559045
INS-IGF2 INS-IGF2 readthrough 0.55886
NKAP NFKB activating protein 0.558127
KIAA1804 mixed lineage kinase 4 0.558127
FREM3 FRAS1 related extracellular matrix 3 0.557764
ENDOD1 endonuclease domain containing 1 0.557402
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.556152
CELF4 CUGBP, Elav-like family member 4 0.555448
FRS2 fibroblast growth factor receptor substrate 2 0.555448
ZNF804B zinc finger protein 804B 0.554925
METTL24 methyltransferase like 24 0.554751
C6ORF58 chromosome 6 open reading frame 58 0.554406
FMN1 formin 1 0.554062
RBKS ribokinase 0.55372
ADCK4 aarF domain containing kinase 4 0.55355
C4ORF19 chromosome 4 open reading frame 19 0.552536
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.552369
AWAT2 acyl-CoA wax alcohol acyltransferase 2 0.552035
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.551209
LAMP2 lysosomal-associated membrane protein 2 0.550718
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 0.550718
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.550718
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.550069
TRIM2 tripartite motif containing 2 0.549747
IQCE IQ motif containing E 0.549107
SDK1 sidekick cell adhesion molecule 1 0.548949
OLFM3 olfactomedin 3 0.548474
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 0.54816
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.548003
CLEC2A C-type lectin domain family 2, member A 0.548003
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1 0.54738
CCSER1 coiled-coil serine-rich protein 1 0.547225
MYO1F myosin IF 0.547225
COL7A1 collagen, type VII, alpha 1 0.546917
KL klotho 0.546917
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.546457
IRAK3 interleukin-1 receptor-associated kinase 3 0.546457
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 0.546457
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 0.546152
PTPRT protein tyrosine phosphatase, receptor type, T 0.545546
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.545396
SGCZ sarcoglycan, zeta 0.545245
PLA2G4E phospholipase A2, group IVE 0.545096
RAB40B RAB40B, member RAS oncogene family 0.544946
TGIF1 TGFB-induced factor homeobox 1 0.544787
SPAG16 sperm associated antigen 16 0.544787
HNF1B HNF1 homeobox B 0.544628
WWOX WW domain containing oxidoreductase 0.544469
SEPT9 septin 9 0.544152
PARVB parvin, beta 0.543994
SH3KBP1 SH3-domain kinase binding protein 1 0.543994
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.543523
CDK13 cyclin-dependent kinase 13 0.542744
MAP3K15 mitogen-activated protein kinase kinase kinase 15 0.542744
FHIT fragile histidine triad 0.542589
ZFPM2 zinc finger protein, FOG family member 2 0.541974
ZHX2 zinc fingers and homeoboxes 2 0.541516
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.54031
CREB3L2 cAMP responsive element binding protein 3-like 2 0.54031
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.54016
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 0.54016
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.540011
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 0.540011
SNX29 sorting nexin 29 0.539714
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.539419
PHF21A PHD finger protein 21A 0.539419
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.539124
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.539124
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.538539
GAS6 growth arrest-specific 6 0.538248
COL4A6 collagen, type IV, alpha 6 0.537815
GRIK4 glutamate receptor, ionotropic, kainate 4 0.537671
AVEN apoptosis, caspase activation inhibitor 0.536671
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.53653
DCC DCC netrin 1 receptor 0.536388
MYO10 myosin X 0.535686
LOC100128554 uncharacterized LOC100128554 0.535269
RGS6 regulator of G-protein signaling 6 0.534853
SYNJ2 synaptojanin 2 0.534853
MED16 mediator complex subunit 16 0.534578
PRKCA protein kinase C, alpha 0.534304
SRRM4 serine/arginine repetitive matrix 4 0.534167
LINC00545 long intergenic non-protein coding RNA 545 0.534167
PRKCQ protein kinase C, theta 0.533758
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.533217
MYO18B myosin XVIIIB 0.533083
PALM2 paralemmin 2 0.532414
PXDNL peroxidasin-like 0.532281
RXRA retinoid X receptor, alpha 0.531884
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.531752
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.53162
TTC3 tetratricopeptide repeat domain 3 0.530835
NPTXR neuronal pentraxin receptor 0.530705
LUZP2 leucine zipper protein 2 0.530705
UPB1 ureidopropionase, beta 0.530446
NCKAP5 NCK-associated protein 5 0.530188
MALRD1 MAM and LDL receptor class A domain containing 1 0.529675
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.529293
CD1A CD1a molecule 0.52866
MTUS2 microtubule associated tumor suppressor candidate 2 0.528535
ADGRF5 adhesion G protein-coupled receptor F5 0.528159
C1ORF106 chromosome 1 open reading frame 106 0.528159
ZNF652 zinc finger protein 652 0.527043
ORC5 origin recognition complex, subunit 5 0.527043
GRIP1 glutamate receptor interacting protein 1 0.526676
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.526676
EDA ectodysplasin A 0.526554
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.525946
NAV2 neuron navigator 2 0.525463
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.525463
KIF13B kinesin family member 13B 0.525103
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.524983
PLA2G12B phospholipase A2, group XIIB 0.524626
PTPRD protein tyrosine phosphatase, receptor type, D 0.524151
ASIC2 acid sensing (proton gated) ion channel 2 0.524033
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.523916
CSRP1 cysteine and glycine-rich protein 1 0.523447
AK8 adenylate kinase 8 0.52333
BLK BLK proto-oncogene, Src family tyrosine kinase 0.52333
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.522865
VSNL1 visinin-like 1 0.522518
ACOXL acyl-CoA oxidase-like 0.522288
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.522174
TNMD tenomodulin 0.521945
JPH3 junctophilin 3 0.521945
NUB1 negative regulator of ubiquitin-like proteins 1 0.521717
COL28A1 collagen, type XXVIII, alpha 1 0.521376
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.521263
FMR1NB fragile X mental retardation 1 neighbor 0.521037
LINC01121 long intergenic non-protein coding RNA 1121 0.520364
TRIM44 tripartite motif containing 44 0.520253
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 0.520253
PALD1 phosphatase domain containing, paladin 1 0.520142
LRGUK leucine-rich repeats and guanylate kinase domain containing 0.520031
HDAC4 histone deacetylase 4 0.51992
CAPG capping protein (actin filament), gelsolin-like 0.519149
CTIF CBP80/20-dependent translation initiation factor 0.519039
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.51893
TNIK TRAF2 and NCK interacting kinase 0.518821
PIWIL4 piwi-like RNA-mediated gene silencing 4 0.518495
ADNP2 ADNP homeobox 2 0.51817
GFRA1 GDNF family receptor alpha 1 0.51817
ANO1 anoctamin 1, calcium activated chloride channel 0.51817
TENM2 teneurin transmembrane protein 2 0.51817
VASH2 vasohibin 2 0.517955
SPATA22 spermatogenesis associated 22 0.517847
DAOA-AS1 DAOA antisense RNA 1 0.517847
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 0.51774
PBX1 pre-B-cell leukemia homeobox 1 0.517633
RPL39 ribosomal protein L39 0.516782
COLEC12 collectin sub-family member 12 0.516782
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.516466
CCDC73 coiled-coil domain containing 73 0.516361
CDH23 cadherin-related 23 0.516256
STAP1 signal transducing adaptor family member 1 0.516256
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.516047
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 0.515943
FNDC3A fibronectin type III domain containing 3A 0.515838
LOC100129636 uncharacterized LOC100129636 0.51563
KRT4 keratin 4, type II 0.515527
GRM8 glutamate receptor, metabotropic 8 0.515216
ZDHHC13 zinc finger, DHHC-type containing 13 0.51399
ADCY2 adenylate cyclase 2 (brain) 0.513687
NAV3 neuron navigator 3 0.513586
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.513586
PCDH19 protocadherin 19 0.513486
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.513285
MID1 midline 1 0.512985
RIMBP2 RIMS binding protein 2 0.512687
ENOSF1 enolase superfamily member 1 0.512588
SYN1 synapsin I 0.512291
COL27A1 collagen, type XXVII, alpha 1 0.511996
SHROOM2 shroom family member 2 0.511996
ZBTB20 zinc finger and BTB domain containing 20 0.511021
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.510732
RNF17 ring finger protein 17 0.51054
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.51054
DPH6 diphthamine biosynthesis 6 0.510444
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.510348
CEP104 centrosomal protein 104kDa 0.510157
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.510157
PRLR prolactin receptor 0.510061
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.509492
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 0.509115
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.50874
CTNND2 catenin (cadherin-associated protein), delta 2 0.508554
HMCN2 hemicentin 2 0.508461
ADORA1 adenosine A1 receptor 0.508461
GPC4 glypican 4 0.507813
GPR176 G protein-coupled receptor 176 0.507629
MKL2 MKL/myocardin-like 2 0.507177
FTO fat mass and obesity associated 0.507177
FNBP1 formin binding protein 1 0.506961
LASP1 LIM and SH3 protein 1 0.506674
COL19A1 collagen, type XIX, alpha 1 0.506247
COL4A2 collagen, type IV, alpha 2 0.506247
DOCK8 dedicator of cytokinesis 8 0.506176
C6ORF183 chromosome 6 open reading frame 183 0.506035
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 0.505894
FAM189A1 family with sequence similarity 189, member A1 0.505753
ERBB4 erb-b2 receptor tyrosine kinase 4 0.505473
LOC100506023 uncharacterized LOC100506023 0.505333
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.505264
PRDM16 PR domain containing 16 0.505194
ZNF724P zinc finger protein 724, pseudogene 0.505055
C2ORF70 chromosome 2 open reading frame 70 0.504298
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.504094
GRID2 glutamate receptor, ionotropic, delta 2 0.503958
CD99L2 CD99 molecule-like 2 0.50389
MAST4 microtubule associated serine/threonine kinase family member 4 0.503687
HLA-DOA major histocompatibility complex, class II, DO alpha 0.503552
CNTN6 contactin 6 0.502883
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.502883
SATL1 spermidine/spermine N1-acetyl transferase-like 1 0.50275
DTD1 D-tyrosyl-tRNA deacylase 1 0.502683
SUN1 Sad1 and UNC84 domain containing 1 0.502485
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 0.502091
HDAC8 histone deacetylase 8 0.502091
OR2J3 olfactory receptor, family 2, subfamily J, member 3 0.50196
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.50144
WDFY2 WD repeat and FYVE domain containing 2 0.50144
UNQ6494 uncharacterized LOC100129066 0.501181
SGSM1 small G protein signaling modulator 1 0.501181
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.501053
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 0.500861
RAP1GAP2 RAP1 GTPase activating protein 2 0.500861
TLE2 transducin-like enhancer of split 2 0.500797
RNF126 ring finger protein 126 0.500478
TENM1 teneurin transmembrane protein 1 0.500478
NEK2 NIMA-related kinase 2 0.500478
DCLK1 doublecortin-like kinase 1 0.500288
NOL4L nucleolar protein 4-like 0.499973
ERICH6B glutamate-rich 6B 0.49991
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.499784
RNF122 ring finger protein 122 0.49941
TLR8 toll-like receptor 8 0.49941
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.499223
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.499099
PDZD2 PDZ domain containing 2 0.499038
SPATA16 spermatogenesis associated 16 0.499038
IQSEC2 IQ motif and Sec7 domain 2 0.499038
SAMD5 sterile alpha motif domain containing 5 0.498914
FER1L6-AS1 FER1L6 antisense RNA 1 0.498546
RGS9BP regulator of G protein signaling 9 binding protein 0.498362
C3ORF20 chromosome 3 open reading frame 20 0.498302
NPR3 natriuretic peptide receptor 3 0.498119
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.498059
PTCHD1 patched domain containing 1 0.497998
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.497877
AGBL1 ATP/GTP binding protein-like 1 0.497636
PACRG PARK2 co-regulated 0.497396
ASPA aspartoacylase 0.496506
PFKP phosphofructokinase, platelet 0.49633
PLXDC2 plexin domain containing 2 0.496271