ampicillin-2030 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the ampicillin-2030 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACAN aggrecan
ATG12 autophagy related 12
ATRN attractin
BLVRB biliverdin reductase B
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C2ORF27A chromosome 2 open reading frame 27A
CACYBP calcyclin binding protein
CADM3 cell adhesion molecule 3
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBY1 chibby homolog 1 (Drosophila)
CD86 CD86 molecule
CLTCL1 clathrin, heavy chain-like 1
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF8 DDB1 and CUL4 associated factor 8
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK3 docking protein 3
EFNB3 ephrin-B3
ELMO2 engulfment and cell motility 2
FAM3A family with sequence similarity 3, member A
FASTK Fas-activated serine/threonine kinase
FKBP9 FK506 binding protein 9, 63 kDa
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GDF9 growth differentiation factor 9
GIMAP5 GTPase, IMAP family member 5
GLI3 GLI family zinc finger 3
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPX2 glutathione peroxidase 2
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H4J histone cluster 1, H4j
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KAT6B K(lysine) acetyltransferase 6B
KAT8 K(lysine) acetyltransferase 8
KLF13 Kruppel-like factor 13
LAD1 ladinin 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LPAR2 lysophosphatidic acid receptor 2
LPP LIM domain containing preferred translocation partner in lipoma
LRRN2 leucine rich repeat neuronal 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTB4R leukotriene B4 receptor
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MED27 mediator complex subunit 27
MED6 mediator complex subunit 6
MIER2 mesoderm induction early response 1, family member 2
MPZL1 myelin protein zero-like 1
MTMR3 myotubularin related protein 3
N4BP1 NEDD4 binding protein 1
NDRG2 NDRG family member 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NINJ2 ninjurin 2
NIPAL3 NIPA-like domain containing 3
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
OLFM1 olfactomedin 1
PAOX polyamine oxidase (exo-N4-amino)
PCGF2 polycomb group ring finger 2
PCIF1 PDX1 C-terminal inhibiting factor 1
PELP1 proline, glutamate and leucine rich protein 1
PILRB paired immunoglobin-like type 2 receptor beta
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPID peptidylprolyl isomerase D
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRR14L proline rich 14-like
PRSS53 protease, serine, 53
RAB33A RAB33A, member RAS oncogene family
REC8 REC8 meiotic recombination protein
RIN3 Ras and Rab interactor 3
SH2D3A SH2 domain containing 3A
SIPA1 signal-induced proliferation-associated 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNJ2 synaptojanin 2
TBC1D4 TBC1 domain family, member 4
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TM2D1 TM2 domain containing 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPRA1 transmembrane protein, adipocyte asscociated 1
TRABD TraB domain containing
TRIM62 tripartite motif containing 62
TRIM68 tripartite motif containing 68
TSPYL2 TSPY-like 2
TTLL4 tubulin tyrosine ligase-like family member 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR61 WD repeat domain 61

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACSL4 acyl-CoA synthetase long-chain family member 4
AIDA axin interactor, dorsalization associated
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ASCC1 activating signal cointegrator 1 complex subunit 1
ATAD2B ATPase family, AAA domain containing 2B
ATG2A autophagy related 2A
C6ORF47 chromosome 6 open reading frame 47
C9ORF40 chromosome 9 open reading frame 40
CHEK2 checkpoint kinase 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLP1 cleavage and polyadenylation factor I subunit 1
CNTD2 cyclin N-terminal domain containing 2
CTSG cathepsin G
CTSK cathepsin K
DENND4A DENN/MADD domain containing 4A
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DPF2 D4, zinc and double PHD fingers family 2
DPH2 DPH2 homolog (S. cerevisiae)
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
ERCC3 excision repair cross-complementation group 3
FBXL15 F-box and leucine-rich repeat protein 15
FCHSD2 FCH and double SH3 domains 2
FIG4 FIG4 phosphoinositide 5-phosphatase
FPGT fucose-1-phosphate guanylyltransferase
FUBP3 far upstream element (FUSE) binding protein 3
GAB2 GRB2-associated binding protein 2
GCLM glutamate-cysteine ligase, modifier subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GPR183 G protein-coupled receptor 183
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRPR gastrin-releasing peptide receptor
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HIRA histone cell cycle regulator
HIST3H2A histone cluster 3, H2a
HYI hydroxypyruvate isomerase (putative)
IGFLR1 IGF-like family receptor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL2RG interleukin 2 receptor, gamma
IMPAD1 inositol monophosphatase domain containing 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
ISOC1 isochorismatase domain containing 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIF13B kinesin family member 13B
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A2 leucine rich repeat containing 37, member A2
MAEA macrophage erythroblast attacher
MAGOHB mago-nashi homolog B (Drosophila)
MAN2B2 mannosidase, alpha, class 2B, member 2
MAPK3 mitogen-activated protein kinase 3
MFF mitochondrial fission factor
MMP2 matrix metallopeptidase 2
MON1B MON1 secretory trafficking family member B
MTERF1 mitochondrial transcription termination factor 1
MTERF4 mitochondrial transcription termination factor 4
NECAB3 N-terminal EF-hand calcium binding protein 3
NOTCH1 notch 1
NRBP1 nuclear receptor binding protein 1
PAQR4 progestin and adipoQ receptor family member IV
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PODNL1 podocan-like 1
POTEKP POTE ankyrin domain family, member K, pseudogene
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RPP38 ribonuclease P/MRP 38kDa subunit
SDHAF3 succinate dehydrogenase complex assembly factor 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SIRT6 sirtuin 6
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC39A7 solute carrier family 39 (zinc transporter), member 7
TESK2 testis-specific kinase 2
TEX40 testis expressed 40
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM14A transmembrane protein 14A
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPRSS6 transmembrane protease, serine 6
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TOB1 transducer of ERBB2, 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USB1 U6 snRNA biogenesis 1
VCPKMT valosin containing protein lysine (K) methyltransferase
WDR73 WD repeat domain 73
XDH xanthine dehydrogenase
XPA xeroderma pigmentosum, complementation group A
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF8 zinc finger protein 8