amphotericin B-6303 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the amphotericin B-6303 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACAN aggrecan
ADTRP androgen-dependent TFPI-regulating protein
ARHGAP33 Rho GTPase activating protein 33
ARID1A AT rich interactive domain 1A (SWI-like)
ASTN1 astrotactin 1
ATG10 autophagy related 10
ATG3 autophagy related 3
ATXN1 ataxin 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CCNK cyclin K
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH8 cadherin 8, type 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CLEC4E C-type lectin domain family 4, member E
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
EMX1 empty spiracles homeobox 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERC2-IT1 ERC2 intronic transcript 1
FYB FYN binding protein
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HMOX1 heme oxygenase 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPS1 Hermansky-Pudlak syndrome 1
ICAM1 intercellular adhesion molecule 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1107 KIAA1107
KIDINS220 kinase D-interacting substrate, 220kDa
KRT75 keratin 75, type II
KYNU kynureninase
LARP4B La ribonucleoprotein domain family, member 4B
LINC00574 long intergenic non-protein coding RNA 574
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYO7A myosin VIIA
PAPPA2 pappalysin 2
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHF7 PHD finger protein 7
PLK3 polo-like kinase 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRODH2 proline dehydrogenase (oxidase) 2
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB11B RAB11B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASAL2 RAS protein activator like 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RERE arginine-glutamic acid dipeptide (RE) repeats
RHEB Ras homolog enriched in brain
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPH3A rabphilin 3A
RTN2 reticulon 2
SAMD9 sterile alpha motif domain containing 9
SERHL2 serine hydrolase-like 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAP25 synaptosomal-associated protein, 25kDa
SOS2 son of sevenless homolog 2 (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
SRF serum response factor (c-fos serum response element-binding transcription factor)
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STX2 syntaxin 2
TBL1Y transducin (beta)-like 1, Y-linked
TGFB2 transforming growth factor, beta 2
TLX2 T-cell leukemia homeobox 2
TMEM53 transmembrane protein 53
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRABD TraB domain containing
TRAF3IP2 TRAF3 interacting protein 2
TUBGCP2 tubulin, gamma complex associated protein 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP19 ubiquitin specific peptidase 19
VAV3 vav 3 guanine nucleotide exchange factor
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZMAT5 zinc finger, matrin-type 5
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAT1 adenosine deaminase, tRNA-specific 1
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGAP10 Rho GTPase activating protein 10
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAMBI BMP and activin membrane-bound inhibitor
C11ORF71 chromosome 11 open reading frame 71
C17ORF70 chromosome 17 open reading frame 70
C1ORF159 chromosome 1 open reading frame 159
CASD1 CAS1 domain containing 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEP72 centrosomal protein 72kDa
CEP85 centrosomal protein 85kDa
CIDEC cell death-inducing DFFA-like effector c
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPA4 carboxypeptidase A4
CRIP1 cysteine-rich protein 1 (intestinal)
CRYBA2 crystallin, beta A2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
EPHA4 EPH receptor A4
FBXO46 F-box protein 46
FER fer (fps/fes related) tyrosine kinase
FGGY FGGY carbohydrate kinase domain containing
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GCHFR GTP cyclohydrolase I feedback regulator
GID4 GID complex subunit 4
GLT8D2 glycosyltransferase 8 domain containing 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH2L G patch domain containing 2-like
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IDI2-AS1 IDI2 antisense RNA 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITPKC inositol-trisphosphate 3-kinase C
JMJD4 jumonji domain containing 4
KDM4D lysine (K)-specific demethylase 4D
KLF2 Kruppel-like factor 2
LPAR6 lysophosphatidic acid receptor 6
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGEF1 melanoma antigen family F1
MAPK12 mitogen-activated protein kinase 12
MAPK3 mitogen-activated protein kinase 3
MBTD1 mbt domain containing 1
MUC3A mucin 3A, cell surface associated
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5DC3 5'-nucleotidase domain containing 3
OLFML2A olfactomedin-like 2A
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
ORAI3 ORAI calcium release-activated calcium modulator 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PHC1 polyhomeotic homolog 1 (Drosophila)
PHGDH phosphoglycerate dehydrogenase
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
RECQL4 RecQ protein-like 4
RNH1 ribonuclease/angiogenin inhibitor 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC12A8 solute carrier family 12, member 8
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT17 synaptotagmin XVII
TAGLN3 transgelin 3
TKFC triokinase/FMN cyclase
TMBIM1 transmembrane BAX inhibitor motif containing 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSKU tsukushi, small leucine rich proteoglycan
TSPAN8 tetraspanin 8
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
WDR18 WD repeat domain 18
XAB2 XPA binding protein 2
ZBTB39 zinc finger and BTB domain containing 39
ZFP36 ZFP36 ring finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMYM3 zinc finger, MYM-type 3
ZNF197 zinc finger protein 197
ZNF324 zinc finger protein 324
ZNF408 zinc finger protein 408
ZNF442 zinc finger protein 442
ZNF816 zinc finger protein 816
ZNF862 zinc finger protein 862