amnestic disorder Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information. (Human Disease Ontology, DOID_10914)
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Genes

211 genes co-occuring with the disease amnestic disorder in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ACHE acetylcholinesterase (Yt blood group) 1.83863
PREP prolyl endopeptidase 1.70087
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.48604
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.37556
CHAT choline O-acetyltransferase 1.37425
BCHE butyrylcholinesterase 1.35028
POMC proopiomelanocortin 1.16649
CA1 carbonic anhydrase I 1.16606
LYPLA1 lysophospholipase I 1.12952
CNR1 cannabinoid receptor 1 (brain) 1.09839
S100B S100 calcium binding protein B 1.09545
PDYN prodynorphin 1.09293
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.08202
BDNF brain-derived neurotrophic factor 1.0606
SOCS2 suppressor of cytokine signaling 2 1.05765
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 1.03114
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.01427
IMPACT impact RWD domain protein 0.99233
AVP arginine vasopressin 0.9717
CREB1 cAMP responsive element binding protein 1 0.966244
FOS FBJ murine osteosarcoma viral oncogene homolog 0.95369
RTP1 receptor (chemosensory) transporter protein 1 0.930828
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.921323
RTN4RL1 reticulon 4 receptor-like 1 0.890078
NPS neuropeptide S 0.875738
CNOT1 CCR4-NOT transcription complex, subunit 1 0.850354
LNPEP leucyl/cystinyl aminopeptidase 0.842163
NGF nerve growth factor (beta polypeptide) 0.826589
DSTN destrin (actin depolymerizing factor) 0.820847
STS steroid sulfatase (microsomal), isozyme S 0.808539
LGI1 leucine-rich, glioma inactivated 1 0.806488
DRD2 dopamine receptor D2 0.804436
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 0.802795
TRH thyrotropin-releasing hormone 0.801974
PTK7 protein tyrosine kinase 7 (inactive) 0.787623
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.783936
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.776568
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.776159
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.766351
ARC activity-regulated cytoskeleton-associated protein 0.763902
PRSS21 protease, serine, 21 (testisin) 0.758601
HRH3 histamine receptor H3 0.748424
RPIA ribose 5-phosphate isomerase A 0.738271
C9ORF72 chromosome 9 open reading frame 72 0.732191
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.719654
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.71925
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.716021
GRM1 glutamate receptor, metabotropic 1 0.708364
CA10 carbonic anhydrase X 0.70233
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.690694
CNOT2 CCR4-NOT transcription complex, subunit 2 0.677105
APOE apolipoprotein E 0.67312
CYCS cytochrome c, somatic 0.667152
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.6608
MEA1 male-enhanced antigen 1 0.654067
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.653671
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.643404
LOR loricrin 0.636315
THEM5 thioesterase superfamily member 5 0.619834
VPREB1 pre-B lymphocyte 1 0.609276
GRM5 glutamate receptor, metabotropic 5 0.608885
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.605762
SPAG5 sperm associated antigen 5 0.592116
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 0.590558
SST somatostatin 0.58433
MTX2 metaxin 2 0.577716
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.570329
DCX doublecortin 0.550911
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.547419
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.547419
OPRM1 opioid receptor, mu 1 0.538118
DRD3 dopamine receptor D3 0.526518
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.517649
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.510344
NQO2 NAD(P)H dehydrogenase, quinone 2 0.505739
SOD2 superoxide dismutase 2, mitochondrial 0.503824
CHRM1 cholinergic receptor, muscarinic 1 0.490454
MC5R melanocortin 5 receptor 0.481705
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.481325
TAC1 tachykinin, precursor 1 0.471468
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.464283
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.459373
NLE1 notchless homolog 1 (Drosophila) 0.451454
HRH1 histamine receptor H1 0.450701
CHRM3 cholinergic receptor, muscarinic 3 0.43941
GDF5 growth differentiation factor 5 0.433397
CCK cholecystokinin 0.433397
MGP matrix Gla protein 0.423265
DDN dendrin 0.415398
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.412405
NCAM1 neural cell adhesion molecule 1 0.411283
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.408292
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.407172
ADAM23 ADAM metallopeptidase domain 23 0.406425
TAS1R1 taste receptor, type 1, member 1 0.403064
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.400453
GPX5 glutathione peroxidase 5 0.388909
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.387794
GPX4 glutathione peroxidase 4 0.385936
GLUL glutamate-ammonia ligase 0.385193
DPP6 dipeptidyl-peptidase 6 0.378885
VIP vasoactive intestinal peptide 0.371107
GPX1 glutathione peroxidase 1 0.370737
TARDBP TAR DNA binding protein 0.364454
MAPT microtubule-associated protein tau 0.362978
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.361133
CYTIP cytohesin 1 interacting protein 0.358551
ADAM22 ADAM metallopeptidase domain 22 0.356709
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.355235
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.354131
KIAA0101 KIAA0101 0.351187
XPR1 xenotropic and polytropic retrovirus receptor 1 0.344207
DUSP5 dual specificity phosphatase 5 0.337975
CORT cortistatin 0.337242
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.331756
ENO2 enolase 2 (gamma, neuronal) 0.328105
SPA17 sperm autoantigenic protein 17 0.325187
DAD1 defender against cell death 1 0.323365
NPPB natriuretic peptide B 0.319363
UBQLN2 ubiquilin 2 0.318999
NPY neuropeptide Y 0.318999
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.318272
PNMA2 paraneoplastic Ma antigen 2 0.316092
HOMER1 homer scaffolding protein 1 0.315366
WRAP73 WD repeat containing, antisense to TP73 0.313189
VGF VGF nerve growth factor inducible 0.305226
CAT catalase 0.304503
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.301976
AANAT aralkylamine N-acetyltransferase 0.301615
EGR1 early growth response 1 0.301615
DHH desert hedgehog 0.301615
INS insulin 0.301254
NTS neurotensin 0.295851
TH tyrosine hydroxylase 0.295492
ADAM28 ADAM metallopeptidase domain 28 0.286519
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.284013
SMTNL1 smoothelin-like 1 0.281868
STXBP1 syntaxin binding protein 1 0.27794
MC3R melanocortin 3 receptor 0.268687
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.263368
TACR3 tachykinin receptor 3 0.261952
NPSR1 neuropeptide S receptor 1 0.260538
OXT oxytocin/neurophysin I prepropeptide 0.256652
CA14 carbonic anhydrase XIV 0.252422
GFAP glial fibrillary acidic protein 0.251718
GRP gastrin-releasing peptide 0.238403
ATG4C autophagy related 4C, cysteine peptidase 0.236312
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.235964
ADCY2 adenylate cyclase 2 (brain) 0.231448
SLC16A4 solute carrier family 16, member 4 0.22937
DPYSL2 dihydropyrimidinase-like 2 0.225573
DNAH8 dynein, axonemal, heavy chain 8 0.224884
MBL2 mannose-binding lectin (protein C) 2, soluble 0.22308
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.220424
SCN2A sodium channel, voltage gated, type II alpha subunit 0.215992
HRH2 histamine receptor H2 0.214297
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.213621
EN1 engrailed homeobox 1 0.208245
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.20658
TACR2 tachykinin receptor 2 0.200331
IL1B interleukin 1, beta 0.198709
THY1 Thy-1 cell surface antigen 0.19742
GSR glutathione reductase 0.195183
MRPL49 mitochondrial ribosomal protein L49 0.194865
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.194865
HRH4 histamine receptor H4 0.192344
HBD hemoglobin, delta 0.180084
CLDN11 claudin 11 0.177851
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.176757
MRI1 methylthioribose-1-phosphate isomerase 1 0.176757
PLA2G1B phospholipase A2, group IB (pancreas) 0.176215
ACSL1 acyl-CoA synthetase long-chain family member 1 0.173571
PVALB parvalbumin 0.170789
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.169812
BTNL2 butyrophilin-like 2 0.166995
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.162908
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.161523
IFITM2 interferon induced transmembrane protein 2 0.161523
APP amyloid beta (A4) precursor protein 0.160761
GRN granulin 0.160387
HTN3 histatin 3 0.159838
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.159838
PSEN1 presenilin 1 0.158266
NMT1 N-myristoyltransferase 1 0.144886
CRLF1 cytokine receptor-like factor 1 0.144582
INA internexin neuronal intermediate filament protein, alpha 0.144357
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.143467
WIPF2 WAS/WASL interacting protein family, member 2 0.143072
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.142864
IL1R1 interleukin 1 receptor, type I 0.142759
PER2 period circadian clock 2 0.142391
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.142341
PDE5A phosphodiesterase 5A, cGMP-specific 0.142255
HAND2 heart and neural crest derivatives expressed 2 0.142059
PGRMC1 progesterone receptor membrane component 1 0.140875
LARS leucyl-tRNA synthetase 0.140801
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.140492
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.139694
STX1A syntaxin 1A (brain) 0.13818
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.137967
ENO1 enolase 1, (alpha) 0.137957
CA4 carbonic anhydrase IV 0.137193
F2R coagulation factor II (thrombin) receptor 0.13597
KMT2A lysine (K)-specific methyltransferase 2A 0.135915
F9 coagulation factor IX 0.134506
CARD17 caspase recruitment domain family, member 17 0.134126
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.13348
NOTCH3 notch 3 0.132183
GSK3B glycogen synthase kinase 3 beta 0.130952
NOTCH4 notch 4 0.130451
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.126797