| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the amitriptyline-6353 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AMT | aminomethyltransferase |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| APOL6 | apolipoprotein L, 6 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARRB2 | arrestin, beta 2 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BBC3 | BCL2 binding component 3 |
| BIN1 | bridging integrator 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD24 | CD24 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPNE7 | copine VII |
| CTAGE5 | CTAGE family, member 5 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXXC4 | CXXC finger protein 4 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DENND3 | DENN/MADD domain containing 3 |
| DICER1 | dicer 1, ribonuclease type III |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| ETV5 | ets variant 5 |
| FGL2 | fibrinogen-like 2 |
| FOSL2 | FOS-like antigen 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GPR107 | G protein-coupled receptor 107 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXC10 | homeobox C10 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| IFT122 | intraflagellar transport 122 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL6 | interleukin 6 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| MAGEB2 | melanoma antigen family B2 |
| MAK | male germ cell-associated kinase |
| MINK1 | misshapen-like kinase 1 |
| MST1L | macrophage stimulating 1-like |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOX1 | NADPH oxidase 1 |
| OSMR | oncostatin M receptor |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHF1 | PHD finger protein 1 |
| PHF20 | PHD finger protein 20 |
| PLCD1 | phospholipase C, delta 1 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PQBP1 | polyglutamine binding protein 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB36 | RAB36, member RAS oncogene family |
| RAB3B | RAB3B, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS12 | regulator of G-protein signaling 12 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD6 | SMAD family member 6 |
| SMAD7 | SMAD family member 7 |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| STBD1 | starch binding domain 1 |
| STK24 | serine/threonine kinase 24 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TGFB2 | transforming growth factor, beta 2 |
| THBD | thrombomodulin |
| TMEM231 | transmembrane protein 231 |
| TMEM50B | transmembrane protein 50B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UBE4B | ubiquitination factor E4B |
| VASP | vasodilator-stimulated phosphoprotein |
| WIZ | widely interspaced zinc finger motifs |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANOS1 | anosmin 1 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP10D | ATPase, class V, type 10D |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAK1 | BCL2-antagonist/killer 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C7ORF49 | chromosome 7 open reading frame 49 |
| CAPN5 | calpain 5 |
| CENPO | centromere protein O |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN11 | claudin 11 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDN | dendrin |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| E2F8 | E2F transcription factor 8 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FOXC1 | forkhead box C1 |
| FUZ | fuzzy planar cell polarity protein |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRAMD1B | GRAM domain containing 1B |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HDAC7 | histone deacetylase 7 |
| HOXA6 | homeobox A6 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL11RA | interleukin 11 receptor, alpha |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KIAA0753 | KIAA0753 |
| KIF13B | kinesin family member 13B |
| KLHL26 | kelch-like family member 26 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MYOZ3 | myozenin 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PC | pyruvate carboxylase |
| PCTP | phosphatidylcholine transfer protein |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PTGFR | prostaglandin F receptor (FP) |
| RAB3A | RAB3A, member RAS oncogene family |
| RGCC | regulator of cell cycle |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SCG2 | secretogranin II |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SELENBP1 | selenium binding protein 1 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMA4 | glucuronidase, beta pseudogene |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPAG4 | sperm associated antigen 4 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SYNPO | synaptopodin |
| TAGLN | transgelin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TMEM8A | transmembrane protein 8A |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRIM66 | tripartite motif containing 66 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN8 | tetraspanin 8 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF571 | zinc finger protein 571 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
