aminohippuric acid-5394 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the aminohippuric acid-5394 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADCY2 adenylate cyclase 2 (brain)
ADGRB3 adhesion G protein-coupled receptor B3
AFF1 AF4/FMR2 family, member 1
ALOX12 arachidonate 12-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AQP3 aquaporin 3 (Gill blood group)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARTN artemin
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
C1ORF54 chromosome 1 open reading frame 54
C21ORF2 chromosome 21 open reading frame 2
C2ORF72 chromosome 2 open reading frame 72
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALCB calcitonin-related polypeptide beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC30 coiled-coil domain containing 30
CDA cytidine deaminase
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDRT1 CMT1A duplicated region transcript 1
CFHR4 complement factor H-related 4
CLCN7 chloride channel, voltage-sensitive 7
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLMN calmin (calponin-like, transmembrane)
CNN1 calponin 1, basic, smooth muscle
COL5A1 collagen, type V, alpha 1
COL9A3 collagen, type IX, alpha 3
CORO7 coronin 7
CPED1 cadherin-like and PC-esterase domain containing 1
CRYGC crystallin, gamma C
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNS cystinosin, lysosomal cystine transporter
DMWD dystrophia myotonica, WD repeat containing
EDA ectodysplasin A
EFS embryonal Fyn-associated substrate
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FYB FYN binding protein
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLRA1 glycine receptor, alpha 1
GLS glutaminase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GSAP gamma-secretase activating protein
HGD homogentisate 1,2-dioxygenase
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGA9 integrin, alpha 9
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JAK3 Janus kinase 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KRT83 keratin 83, type II
LAT2 linker for activation of T cells family, member 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMX1B LIM homeobox transcription factor 1, beta
LTBP4 latent transforming growth factor beta binding protein 4
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MBD2 methyl-CpG binding domain protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MOGAT2 monoacylglycerol O-acyltransferase 2
MUC3B mucin 3B, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NNAT neuronatin
NOVA2 neuro-oncological ventral antigen 2
NPY2R neuropeptide Y receptor Y2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PARVB parvin, beta
PAX2 paired box 2
PCLO piccolo presynaptic cytomatrix protein
PCNX pecanex homolog (Drosophila)
PGAP3 post-GPI attachment to proteins 3
PLAT plasminogen activator, tissue
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RSG1 REM2 and RAB-like small GTPase 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
THEMIS2 thymocyte selection associated family member 2
TMC6 transmembrane channel-like 6
TMEM47 transmembrane protein 47
TSPAN9 tetraspanin 9
TTYH1 tweety family member 1
TYMP thymidine phosphorylase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZC3H7B zinc finger CCCH-type containing 7B
ZEB1 zinc finger E-box binding homeobox 1
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD40 ankyrin repeat domain 40
APOLD1 apolipoprotein L domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BST2 bone marrow stromal cell antigen 2
C1ORF159 chromosome 1 open reading frame 159
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
CCDC85C coiled-coil domain containing 85C
CD79B CD79b molecule, immunoglobulin-associated beta
CLSTN2 calsyntenin 2
CORO2A coronin, actin binding protein, 2A
CORT cortistatin
CUZD1 CUB and zona pellucida-like domains 1
DGAT1 diacylglycerol O-acyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELMO3 engulfment and cell motility 3
FAM46C family with sequence similarity 46, member C
FBXO22 F-box protein 22
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFPT2 glutamine-fructose-6-phosphate transaminase 2
HDAC5 histone deacetylase 5
HIST1H1D histone cluster 1, H1d
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIF13A kinesin family member 13A
KITLG KIT ligand
KLF2 Kruppel-like factor 2
KRT15 keratin 15, type I
LIN7A lin-7 homolog A (C. elegans)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP2 low density lipoprotein receptor-related protein 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK12 mitogen-activated protein kinase 12
MBTD1 mbt domain containing 1
MED9 mediator complex subunit 9
METTL16 methyltransferase like 16
MTERF4 mitochondrial transcription termination factor 4
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NCS1 neuronal calcium sensor 1
NLRX1 NLR family member X1
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB3 protocadherin beta 3
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PVRL3 poliovirus receptor-related 3
RAB3D RAB3D, member RAS oncogene family
RECQL4 RecQ protein-like 4
RPGR retinitis pigmentosa GTPase regulator
RRAGB Ras-related GTP binding B
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMIM14 small integral membrane protein 14
SPINK5 serine peptidase inhibitor, Kazal type 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TESC tescalcin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TSSC4 tumor suppressing subtransferable candidate 4
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VLDLR very low density lipoprotein receptor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZNF134 zinc finger protein 134
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254
ZNF35 zinc finger protein 35
ZNF552 zinc finger protein 552
ZNF696 zinc finger protein 696
ZNF770 zinc finger protein 770
ZNHIT2 zinc finger, HIT-type containing 2