altizide-6829 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the altizide-6829 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADRBK1 adrenergic, beta, receptor kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDOB aldolase B, fructose-bisphosphate
AMPD3 adenosine monophosphate deaminase 3
APOE apolipoprotein E
ARNT aryl hydrocarbon receptor nuclear translocator
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BST2 bone marrow stromal cell antigen 2
C1ORF68 chromosome 1 open reading frame 68
CASQ2 calsequestrin 2 (cardiac muscle)
CD48 CD48 molecule
CEP164 centrosomal protein 164kDa
CFAP69 cilia and flagella associated protein 69
CLDN11 claudin 11
CPNE7 copine VII
CSF1R colony stimulating factor 1 receptor
CTNS cystinosin, lysosomal cystine transporter
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DICER1 dicer 1, ribonuclease type III
DOK4 docking protein 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFNB3 ephrin-B3
EFR3B EFR3 homolog B (S. cerevisiae)
FABP3 fatty acid binding protein 3, muscle and heart
FAM120C family with sequence similarity 120C
FAM155A family with sequence similarity 155, member A
FGF2 fibroblast growth factor 2 (basic)
GAP43 growth associated protein 43
GPATCH4 G patch domain containing 4
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1E histone cluster 1, H1e
HLA-DMB major histocompatibility complex, class II, DM beta
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL11 interleukin 11
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KLHDC8A kelch domain containing 8A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIN7A lin-7 homolog A (C. elegans)
LOC100131532 uncharacterized LOC100131532
MAPK14 mitogen-activated protein kinase 14
MASP2 mannan-binding lectin serine peptidase 2
MEOX1 mesenchyme homeobox 1
MFAP3L microfibrillar-associated protein 3-like
MPPE1 metallophosphoesterase 1
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOZ3 myozenin 3
NNAT neuronatin
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP214 nucleoporin 214kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
PDE4DIP phosphodiesterase 4D interacting protein
PER3 period circadian clock 3
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCH2 phospholipase C, eta 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB4 proline-rich protein BstNI subfamily 4
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RASA3 RAS p21 protein activator 3
RBM48 RNA binding motif protein 48
RBP4 retinol binding protein 4, plasma
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLIT2 slit homolog 2 (Drosophila)
SSX3 synovial sarcoma, X breakpoint 3
SYT2 synaptotagmin II
TAT tyrosine aminotransferase
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TGFA transforming growth factor, alpha
TLDC1 TBC/LysM-associated domain containing 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRD T cell receptor delta locus
TTC38 tetratricopeptide repeat domain 38
TULP2 tubby like protein 2
UHRF1BP1L UHRF1 binding protein 1-like
UTRN utrophin
ZNF235 zinc finger protein 235
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ANKRD40 ankyrin repeat domain 40
APOLD1 apolipoprotein L domain containing 1
ARPIN actin-related protein 2/3 complex inhibitor
ASAP1-IT1 ASAP1 intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCL9 B-cell CLL/lymphoma 9
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C14ORF132 chromosome 14 open reading frame 132
C19ORF73 chromosome 19 open reading frame 73
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC121 coiled-coil domain containing 121
CCDC25 coiled-coil domain containing 25
CD302 CD302 molecule
CGA glycoprotein hormones, alpha polypeptide
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CORT cortistatin
CRY2 cryptochrome circadian clock 2
CTNNBIP1 catenin, beta interacting protein 1
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGFL7 EGF-like-domain, multiple 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FER fer (fps/fes related) tyrosine kinase
FGD6 FYVE, RhoGEF and PH domain containing 6
FPGT fucose-1-phosphate guanylyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HDAC4 histone deacetylase 4
HDAC7 histone deacetylase 7
HIST1H4D histone cluster 1, H4d
IDI2-AS1 IDI2 antisense RNA 1
IGSF1 immunoglobulin superfamily, member 1
IL12RB1 interleukin 12 receptor, beta 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KAT2A K(lysine) acetyltransferase 2A
KDM7A lysine (K)-specific demethylase 7A
KIAA0125 KIAA0125
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
KRT15 keratin 15, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LZTR1 leucine-zipper-like transcription regulator 1
MED15 mediator complex subunit 15
NABP2 nucleic acid binding protein 2
NPIPB15 nuclear pore complex interacting protein family, member B15
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PRODH proline dehydrogenase (oxidase) 1
PTDSS2 phosphatidylserine synthase 2
RHOBTB2 Rho-related BTB domain containing 2
RNF219 ring finger protein 219
RRAGB Ras-related GTP binding B
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGK1 serum/glucocorticoid regulated kinase 1
SIX1 SIX homeobox 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A40 solute carrier family 25, member 40
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOWAHC sosondowah ankyrin repeat domain family member C
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STEAP3 STEAP family member 3, metalloreductase
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TBC1D2B TBC1 domain family, member 2B
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TMEM120B transmembrane protein 120B
TOM1 target of myb1 (chicken)
TRABD TraB domain containing
TUBA3C tubulin, alpha 3c
UBTD1 ubiquitin domain containing 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF551 zinc finger protein 551
ZNF701 zinc finger protein 701
ZNF787 zinc finger protein 787