| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the altizide-6829 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPD3 | adenosine monophosphate deaminase 3 |
| APOE | apolipoprotein E |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BST2 | bone marrow stromal cell antigen 2 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CD48 | CD48 molecule |
| CEP164 | centrosomal protein 164kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CLDN11 | claudin 11 |
| CPNE7 | copine VII |
| CSF1R | colony stimulating factor 1 receptor |
| CTNS | cystinosin, lysosomal cystine transporter |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DICER1 | dicer 1, ribonuclease type III |
| DOK4 | docking protein 4 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFNB3 | ephrin-B3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM120C | family with sequence similarity 120C |
| FAM155A | family with sequence similarity 155, member A |
| FGF2 | fibroblast growth factor 2 (basic) |
| GAP43 | growth associated protein 43 |
| GPATCH4 | G patch domain containing 4 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1E | histone cluster 1, H1e |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| ICOS | inducible T-cell co-stimulator |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL11 | interleukin 11 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
| KCNA10 | potassium channel, voltage gated shaker related subfamily A, member 10 |
| KLHDC8A | kelch domain containing 8A |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC100131532 | uncharacterized LOC100131532 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MEOX1 | mesenchyme homeobox 1 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MPPE1 | metallophosphoesterase 1 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL10 | myosin, light chain 10, regulatory |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| MYOZ3 | myozenin 3 |
| NNAT | neuronatin |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP214 | nucleoporin 214kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ONECUT2 | one cut homeobox 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PER3 | period circadian clock 3 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLCH2 | phospholipase C, eta 2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| RASA3 | RAS p21 protein activator 3 |
| RBM48 | RNA binding motif protein 48 |
| RBP4 | retinol binding protein 4, plasma |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SYT2 | synaptotagmin II |
| TAT | tyrosine aminotransferase |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFA | transforming growth factor, alpha |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRD | T cell receptor delta locus |
| TTC38 | tetratricopeptide repeat domain 38 |
| TULP2 | tubby like protein 2 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UTRN | utrophin |
| ZNF235 | zinc finger protein 235 |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ANKRD40 | ankyrin repeat domain 40 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC25 | coiled-coil domain containing 25 |
| CD302 | CD302 molecule |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CORT | cortistatin |
| CRY2 | cryptochrome circadian clock 2 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HDAC4 | histone deacetylase 4 |
| HDAC7 | histone deacetylase 7 |
| HIST1H4D | histone cluster 1, H4d |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JMJD4 | jumonji domain containing 4 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA0125 | KIAA0125 |
| KLHL25 | kelch-like family member 25 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT15 | keratin 15, type I |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MED15 | mediator complex subunit 15 |
| NABP2 | nucleic acid binding protein 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF219 | ring finger protein 219 |
| RRAGB | Ras-related GTP binding B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCRN3 | secernin 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIX1 | SIX homeobox 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D2B | TBC1 domain family, member 2B |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM120B | transmembrane protein 120B |
| TOM1 | target of myb1 (chicken) |
| TRABD | TraB domain containing |
| TUBA3C | tubulin, alpha 3c |
| UBTD1 | ubiquitin domain containing 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF34 | zinc finger protein 34 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF442 | zinc finger protein 442 |
| ZNF551 | zinc finger protein 551 |
| ZNF701 | zinc finger protein 701 |
| ZNF787 | zinc finger protein 787 |
