altizide-4491 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the altizide-4491 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADM2 adrenomedullin 2
AGTR1 angiotensin II receptor, type 1
ALDOB aldolase B, fructose-bisphosphate
AMPD1 adenosine monophosphate deaminase 1
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP10B ATPase, class V, type 10B
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
C1ORF61 chromosome 1 open reading frame 61
CCDC132 coiled-coil domain containing 132
CD160 CD160 molecule
CD22 CD22 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD84 CD84 molecule
CDO1 cysteine dioxygenase type 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLEC11A C-type lectin domain family 11, member A
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DSCAM Down syndrome cell adhesion molecule
DST dystonin
DUSP9 dual specificity phosphatase 9
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ECE1 endothelin converting enzyme 1
EDRF1 erythroid differentiation regulatory factor 1
ESRRG estrogen-related receptor gamma
FUBP1 far upstream element (FUSE) binding protein 1
GLB1L galactosidase, beta 1-like
GLB1L2 galactosidase, beta 1-like 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR17 G protein-coupled receptor 17
GREM1 gremlin 1, DAN family BMP antagonist
GSTTP1 glutathione S-transferase theta pseudogene 1
GUCA1A guanylate cyclase activator 1A (retina)
HCRP1 hepatocellular carcinoma-related HCRP1
HOXD1 homeobox D1
HRG histidine-rich glycoprotein
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGL immunoglobulin lambda locus
IZUMO4 IZUMO family member 4
KALRN kalirin, RhoGEF kinase
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KERA keratocan
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KMT2A lysine (K)-specific methyltransferase 2A
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOX lysyl oxidase
LTB4R leukotriene B4 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP3L microfibrillar-associated protein 3-like
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NTF3 neurotrophin 3
NUDCD3 NudC domain containing 3
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PACS1 phosphofurin acidic cluster sorting protein 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4DIP phosphodiesterase 4D interacting protein
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLIN2 perilipin 2
POFUT1 protein O-fucosyltransferase 1
POFUT2 protein O-fucosyltransferase 2
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRB protein tyrosine phosphatase, receptor type, B
PYGO1 pygopus family PHD finger 1
REC8 REC8 meiotic recombination protein
RGS3 regulator of G-protein signaling 3
RPH3A rabphilin 3A
RSG1 REM2 and RAB-like small GTPase 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIKE1 suppressor of IKBKE 1
SLC16A6 solute carrier family 16, member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STEAP4 STEAP family member 4
STK24 serine/threonine kinase 24
SYT13 synaptotagmin XIII
TCF25 transcription factor 25 (basic helix-loop-helix)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TRA T cell receptor alpha locus
TSKS testis-specific serine kinase substrate
TTC12 tetratricopeptide repeat domain 12
TTC38 tetratricopeptide repeat domain 38
TTLL4 tubulin tyrosine ligase-like family member 4
UPK3A uroplakin 3A
VIPR2 vasoactive intestinal peptide receptor 2
WRNIP1 Werner helicase interacting protein 1
WSB1 WD repeat and SOCS box containing 1
XAF1 XIAP associated factor 1
ZBTB33 zinc finger and BTB domain containing 33

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATG10 autophagy related 10
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
BEND5 BEN domain containing 5
BFSP1 beaded filament structural protein 1, filensin
BTC betacellulin
CCDC186 coiled-coil domain containing 186
CDKL3 cyclin-dependent kinase-like 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHMP1A charged multivesicular body protein 1A
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CISH cytokine inducible SH2-containing protein
CRELD1 cysteine-rich with EGF-like domains 1
CTC1 CTS telomere maintenance complex component 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DPF3 D4, zinc and double PHD fingers, family 3
EFNB1 ephrin-B1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERAP2 endoplasmic reticulum aminopeptidase 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FOXN2 forkhead box N2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALK1 galactokinase 1
GDAP2 ganglioside induced differentiation associated protein 2
GPR19 G protein-coupled receptor 19
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB5 homeobox B5
IL33 interleukin 33
IL6 interleukin 6
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM4D lysine (K)-specific demethylase 4D
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
LOC257152 uncharacterized LOC257152
LRRK1 leucine-rich repeat kinase 1
MDFI MyoD family inhibitor
MFAP2 microfibrillar-associated protein 2
MMP13 matrix metallopeptidase 13
MTG1 mitochondrial ribosome-associated GTPase 1
MVP major vault protein
MXRA8 matrix-remodelling associated 8
MYO1F myosin IF
NARFL nuclear prelamin A recognition factor-like
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NPFFR1 neuropeptide FF receptor 1
NTSR1 neurotensin receptor 1 (high affinity)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OGDHL oxoglutarate dehydrogenase-like
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCOLCE procollagen C-endopeptidase enhancer
PDE12 phosphodiesterase 12
PDZK1 PDZ domain containing 1
PER3 period circadian clock 3
PLD2 phospholipase D2
PODXL2 podocalyxin-like 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS22 protease, serine, 22
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RPL13P5 ribosomal protein L13 pseudogene 5
RPS14P3 ribosomal protein S14 pseudogene 3
RUSC2 RUN and SH3 domain containing 2
SH2D2A SH2 domain containing 2A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPEG SPEG complex locus
SRD5A3 steroid 5 alpha-reductase 3
STRN striatin, calmodulin binding protein
SYNGR3 synaptogyrin 3
TAOK1 TAO kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UNC119 unc-119 homolog (C. elegans)
VWA1 von Willebrand factor A domain containing 1
WDR33 WD repeat domain 33
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF214 zinc finger protein 214
ZNF222 zinc finger protein 222
ZNF606 zinc finger protein 606
ZNF711 zinc finger protein 711
ZNF76 zinc finger protein 76
ZW10 zw10 kinetochore protein