altered response to myocardial infarction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description change in the physiological response to necrosis of the cardiac tissue, often resulting from the sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors (Mammalian Phenotype Ontology, MP_0000343)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000343
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Genes

70 gene mutations causing the altered response to myocardial infarction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
AGTR2 angiotensin II receptor, type 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AK1 adenylate kinase 1
APOD apolipoprotein D
BBC3 BCL2 binding component 3
BECN1 beclin 1, autophagy related
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CCL13 chemokine (C-C motif) ligand 13
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CYSLTR2 cysteinyl leukotriene receptor 2
DUSP6 dual specificity phosphatase 6
ESR2 estrogen receptor 2 (ER beta)
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGF2 fibroblast growth factor 2 (basic)
G6PD glucose-6-phosphate dehydrogenase
GDF15 growth differentiation factor 15
GSK3B glycogen synthase kinase 3 beta
HMOX1 heme oxygenase 1
IL10 interleukin 10
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LEPR leptin receptor
LIMS2 LIM and senescent cell antigen-like domains 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MASP2 mannan-binding lectin serine peptidase 2
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
NCF1 neutrophil cytosolic factor 1
NGFR nerve growth factor receptor
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS2 nitric oxide synthase 2, inducible
NPR1 natriuretic peptide receptor 1
NT5E 5'-nucleotidase, ecto (CD73)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PLA2G10 phospholipase A2, group X
PLA2G5 phospholipase A2, group V
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PRKCE protein kinase C, epsilon
RCAN1 regulator of calcineurin 1
RFX4 regulatory factor X, 4 (influences HLA class II expression)
RNLS renalase, FAD-dependent amine oxidase
RYR2 ryanodine receptor 2 (cardiac)
SOD1 superoxide dismutase 1, soluble
SPP1 secreted phosphoprotein 1
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
TGM2 transglutaminase 2
THBD thrombomodulin
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP4 TIMP metallopeptidase inhibitor 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TP53 tumor protein p53
TSC2 tuberous sclerosis 2
VEGFB vascular endothelial growth factor B
VWF von Willebrand factor
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta