altered response to cns ischemic injury Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description altered response to lack of adequate blood flow, due to trauma or disease, to support the normal functioning of a tissue in the central nervous system (Mammalian Phenotype Ontology, MP_0003075)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003075
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Genes

66 gene mutations causing the altered response to cns ischemic injury phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA2A adenosine A2a receptor
APOE apolipoprotein E
AQP4 aquaporin 4
C3 complement component 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CD1D CD1d molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNR1 cannabinoid receptor 1 (brain)
CNTF ciliary neurotrophic factor
CST3 cystatin C
CX3CL1 chemokine (C-X3-C motif) ligand 1
DAPK1 death-associated protein kinase 1
DCR Down syndrome chromosome region
EGR1 early growth response 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAIM2 Fas apoptotic inhibitory molecule 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GSN gelsolin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA1B heat shock 70kDa protein 1B
HYOU1 hypoxia up-regulated 1
IL10 interleukin 10
IL18 interleukin 18
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
KCNK2 potassium channel, two pore domain subfamily K, member 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MMP9 matrix metallopeptidase 9
NBEAL2 neurobeachin-like 2
NDRG4 NDRG family member 4
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFE2L2 nuclear factor, erythroid 2-like 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH3 notch 3
NOX4 NADPH oxidase 4
OLFM1 olfactomedin 1
PANX2 pannexin 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLD1 phospholipase D1, phosphatidylcholine-specific
PPIF peptidylprolyl isomerase F
PRKCD protein kinase C, delta
PSPN persephin
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RTN4R reticulon 4 receptor
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SNTA1 syntrophin, alpha 1
STIM2 stromal interaction molecule 2
STIP1 stress-induced phosphoprotein 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UNG uracil-DNA glycosylase
VWF von Willebrand factor