altered response of heart to induced stress Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description change in the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding (Mammalian Phenotype Ontology, MP_0004484)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004484
Similar Terms
Downloads & Tools

Genes

69 gene mutations causing the altered response of heart to induced stress phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
AGTR2 angiotensin II receptor, type 2
APLN apelin
ASPH aspartate beta-hydroxylase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BVES blood vessel epicardial substance
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMTA2 calmodulin binding transcription activator 2
CASQ2 calsequestrin 2 (cardiac muscle)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DUSP6 dual specificity phosphatase 6
EGLN1 egl-9 family hypoxia-inducible factor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FHL1 four and a half LIM domains 1
FLT1 fms-related tyrosine kinase 1
GATA4 GATA binding protein 4
GLRX3 glutaredoxin 3
GPR22 G protein-coupled receptor 22
GRK5 G protein-coupled receptor kinase 5
HRC histidine rich calcium binding protein
INPP5F inositol polyphosphate-5-phosphatase F
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUND jun D proto-oncogene
KLF15 Kruppel-like factor 15
KLF5 Kruppel-like factor 5 (intestinal)
LDB3 LIM domain binding 3
MAOA monoamine oxidase A
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK8 mitogen-activated protein kinase 8
MIR22 microRNA 22
MURC muscle-related coiled-coil protein
MYBPC3 myosin binding protein C, cardiac
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLK3 myosin light chain kinase 3
MYOZ2 myozenin 2
NEK6 NIMA-related kinase 6
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOS1 nitric oxide synthase 1 (neuronal)
NOX4 NADPH oxidase 4
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PLA2G10 phospholipase A2, group X
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCE1 phospholipase C, epsilon 1
POPDC2 popeye domain containing 2
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKCA protein kinase C, alpha
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCAN1 regulator of calcineurin 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RYR2 ryanodine receptor 2 (cardiac)
SFRP2 secreted frizzled-related protein 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
TCAP titin-cap
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TXNIP thioredoxin interacting protein