alsterpaullone-7078 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the alsterpaullone-7078 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACTC1 actin, alpha, cardiac muscle 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ADK adenosine kinase
AHCYL2 adenosylhomocysteinase-like 2
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOLD1 apolipoprotein L domain containing 1
ASPH aspartate beta-hydroxylase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
B9D1 B9 protein domain 1
BCCIP BRCA2 and CDKN1A interacting protein
BCL2L1 BCL2-like 1
BEX1 brain expressed, X-linked 1
BTBD18 BTB (POZ) domain containing 18
C16ORF58 chromosome 16 open reading frame 58
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CELF1 CUGBP, Elav-like family member 1
CHD3 chromodomain helicase DNA binding protein 3
COL13A1 collagen, type XIII, alpha 1
COL21A1 collagen, type XXI, alpha 1
COPA coatomer protein complex, subunit alpha
CORO1B coronin, actin binding protein, 1B
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CUX1 cut-like homeobox 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGAT1 diacylglycerol O-acyltransferase 1
DIDO1 death inducer-obliterator 1
DPP4 dipeptidyl-peptidase 4
DUSP6 dual specificity phosphatase 6
FAXDC2 fatty acid hydroxylase domain containing 2
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GM2A GM2 ganglioside activator
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GTPBP4 GTP binding protein 4
GUCA1B guanylate cyclase activator 1B (retina)
HMGA2 high mobility group AT-hook 2
HOXA10 homeobox A10
HOXA11 homeobox A11
HOXA9 homeobox A9
HOXB2 homeobox B2
HTT huntingtin
IDI2-AS1 IDI2 antisense RNA 1
ITGB5 integrin, beta 5
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JMJD6 jumonji domain containing 6
KIAA0319L KIAA0319-like
KLF6 Kruppel-like factor 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LOC157562 uncharacterized LOC157562
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEA6 melanoma antigen family A6
MFSD11 major facilitator superfamily domain containing 11
NOV nephroblastoma overexpressed
NPDC1 neural proliferation, differentiation and control, 1
OLFML3 olfactomedin-like 3
PDZK1 PDZ domain containing 1
PI3 peptidase inhibitor 3, skin-derived
PRLH prolactin releasing hormone
RAB2A RAB2A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RBKS ribokinase
RFPL3S RFPL3 antisense
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
S100A11 S100 calcium binding protein A11
SAG S-antigen; retina and pineal gland (arrestin)
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG5 secretogranin V
SEC63 SEC63 homolog (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD1B SET domain containing 1B
SFPQ splicing factor proline/glutamine-rich
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPAG16 sperm associated antigen 16
SPATS2L spermatogenesis associated, serine-rich 2-like
STAC SH3 and cysteine rich domain
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCF4 transcription factor 4
TEX40 testis expressed 40
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM161A transmembrane protein 161A
TMEM8A transmembrane protein 8A
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPMT thiopurine S-methyltransferase
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URM1 ubiquitin related modifier 1
WLS wntless Wnt ligand secretion mediator
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB1 zinc finger and BTB domain containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ARHGAP12 Rho GTPase activating protein 12
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ARMC7 armadillo repeat containing 7
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF169 chromosome 14 open reading frame 169
C1ORF106 chromosome 1 open reading frame 106
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK7 cyclin-dependent kinase 7
CDKN2AIP CDKN2A interacting protein
CHD1 chromodomain helicase DNA binding protein 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN4 claudin 4
COA7 cytochrome c oxidase assembly factor 7 (putative)
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTGF connective tissue growth factor
DBF4 DBF4 zinc finger
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
E2F6 E2F transcription factor 6
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ERCC6L excision repair cross-complementation group 6-like
ETAA1 Ewing tumor-associated antigen 1
FADD Fas (TNFRSF6)-associated via death domain
FBXL14 F-box and leucine-rich repeat protein 14
FBXO34 F-box protein 34
FEM1C fem-1 homolog c (C. elegans)
FOXD1 forkhead box D1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR87 G protein-coupled receptor 87
GSPT2 G1 to S phase transition 2
GTF2B general transcription factor IIB
HAUS3 HAUS augmin-like complex, subunit 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFRD1 interferon-related developmental regulator 1
ING3 inhibitor of growth family, member 3
JADE1 jade family PHD finger 1
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KDM3A lysine (K)-specific demethylase 3A
KIN Kin17 DNA and RNA binding protein
LEMD3 LEM domain containing 3
LHFPL2 lipoma HMGIC fusion partner-like 2
LPAR6 lysophosphatidic acid receptor 6
MED17 mediator complex subunit 17
MED23 mediator complex subunit 23
MEPCE methylphosphate capping enzyme
MFSD5 major facilitator superfamily domain containing 5
MGA MGA, MAX dimerization protein
MORC3 MORC family CW-type zinc finger 3
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NRBF2 nuclear receptor binding factor 2
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PMM2 phosphomannomutase 2
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTRH2 peptidyl-tRNA hydrolase 2
RBM4B RNA binding motif protein 4B
RBM7 RNA binding motif protein 7
RNF111 ring finger protein 111
RNF139 ring finger protein 139
RSBN1 round spermatid basic protein 1
S100PBP S100P binding protein
SCAF8 SR-related CTD-associated factor 8
SCO2 SCO2 cytochrome c oxidase assembly protein
SIRT1 sirtuin 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC38A2 solute carrier family 38, member 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYBU syntabulin (syntaxin-interacting)
SYNRG synergin, gamma
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBPL1 TBP-like 1
TGDS TDP-glucose 4,6-dehydratase
TMEM186 transmembrane protein 186
TOB1 transducer of ERBB2, 1
TRIM13 tripartite motif containing 13
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TWIST1 twist family bHLH transcription factor 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR5B WD repeat domain 5B
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF212 zinc finger protein 212
ZNF274 zinc finger protein 274
ZNF365 zinc finger protein 365
ZNF443 zinc finger protein 443
ZNF468 zinc finger protein 468
ZNF85 zinc finger protein 85