alpha-naphthoflavone Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14). (Chemical Entities of Biological Interest Ontology, CHEBI_76995)
External Link http://ctdbase.org/detail.go?type=chem&acc=C011512
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Genes

56 genes/proteins interacting with the chemical alpha-naphthoflavone from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AHR aryl hydrocarbon receptor
AR androgen receptor
ARNT aryl hydrocarbon receptor nuclear translocator
BRCA1 breast cancer 1, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DUSP5 dual specificity phosphatase 5
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
FGF2 fibroblast growth factor 2 (basic)
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IGFBP4 insulin-like growth factor binding protein 4
IL10 interleukin 10
IL1B interleukin 1, beta
JUN jun proto-oncogene
KLK3 kallikrein-related peptidase 3
LHCGR luteinizing hormone/choriogonadotropin receptor
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOG myogenin (myogenic factor 4)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
PGR progesterone receptor
PPARA peroxisome proliferator-activated receptor alpha
PRKCB protein kinase C, beta
PTK2 protein tyrosine kinase 2
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
STAT5B signal transducer and activator of transcription 5B
TNF tumor necrosis factor
TP53 tumor protein p53
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A