alpha-ergocryptine-4374 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the alpha-ergocryptine-4374 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADGRA2 adhesion G protein-coupled receptor A2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALOXE3 arachidonate lipoxygenase 3
ANKRD7 ankyrin repeat domain 7
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP1 bone morphogenetic protein 1
BUD31 BUD31 homolog (S. cerevisiae)
CCKAR cholecystokinin A receptor
CD53 CD53 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHRM2 cholinergic receptor, muscarinic 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNAH9 dynein, axonemal, heavy chain 9
DNALI1 dynein, axonemal, light intermediate chain 1
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ETV4 ets variant 4
FAM182B family with sequence similarity 182, member B
FLT3LG fms-related tyrosine kinase 3 ligand
FSCN1 fascin actin-bundling protein 1
GRM1 glutamate receptor, metabotropic 1
GRM8 glutamate receptor, metabotropic 8
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HP haptoglobin
ICAM5 intercellular adhesion molecule 5, telencephalin
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
IZUMO4 IZUMO family member 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
LAMA4 laminin, alpha 4
LAMC3 laminin, gamma 3
LAMP5 lysosomal-associated membrane protein family, member 5
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRN2 leucine rich repeat neuronal 2
LSP1 lymphocyte-specific protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MED25 mediator complex subunit 25
MIR622 microRNA 622
MST1 macrophage stimulating 1
MUC3B mucin 3B, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MXD4 MAX dimerization protein 4
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NKX2-1 NK2 homeobox 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPPB natriuretic peptide B
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR3A3 olfactory receptor, family 3, subfamily A, member 3
OSBPL10 oxysterol binding protein-like 10
PON1 paraoxonase 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRM protein tyrosine phosphatase, receptor type, M
R3HDM1 R3H domain containing 1
RAB3B RAB3B, member RAS oncogene family
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RANBP3 RAN binding protein 3
RBM12B RNA binding motif protein 12B
REC8 REC8 meiotic recombination protein
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RUNX1 runt-related transcription factor 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SGK2 serum/glucocorticoid regulated kinase 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC39A9 solute carrier family 39, member 9
SPTBN5 spectrin, beta, non-erythrocytic 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SULT4A1 sulfotransferase family 4A, member 1
TAS2R3 taste receptor, type 2, member 3
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD12 tudor domain containing 12
TP63 tumor protein p63
UGT8 UDP glycosyltransferase 8
VN1R1 vomeronasal 1 receptor 1
XYLB xylulokinase homolog (H. influenzae)
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AEN apoptosis enhancing nuclease
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C1ORF105 chromosome 1 open reading frame 105
C9ORF40 chromosome 9 open reading frame 40
CA5BP1 carbonic anhydrase VB pseudogene 1
CALML5 calmodulin-like 5
CAMK1 calcium/calmodulin-dependent protein kinase I
CASD1 CAS1 domain containing 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX7 chromobox homolog 7
CCDC69 coiled-coil domain containing 69
CCDC86 coiled-coil domain containing 86
CCNJ cyclin J
CFHR4 complement factor H-related 4
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
DLK2 delta-like 2 homolog (Drosophila)
DPY19L1P1 DPY19L1 pseudogene 1
ELSPBP1 epididymal sperm binding protein 1
FANCE Fanconi anemia, complementation group E
FBXL2 F-box and leucine-rich repeat protein 2
FBXO5 F-box protein 5
FOXC1 forkhead box C1
GAN gigaxonin
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR143 G protein-coupled receptor 143
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AL histone cluster 1, H2al
IFI6 interferon, alpha-inducible protein 6
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM7A lysine (K)-specific demethylase 7A
KIAA0355 KIAA0355
KIAA1551 KIAA1551
KIF13B kinesin family member 13B
KLF11 Kruppel-like factor 11
KRT83 keratin 83, type II
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LOC157562 uncharacterized LOC157562
LOC390998 ribosomal protein L10 pseudogene
LYRM9 LYR motif containing 9
MRPL44 mitochondrial ribosomal protein L44
MTCP1 mature T-cell proliferation 1
MUC3A mucin 3A, cell surface associated
NBEA neurobeachin
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME5 NME/NM23 family member 5
NR1D2 nuclear receptor subfamily 1, group D, member 2
PCDHA9 protocadherin alpha 9
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPT2 palmitoyl-protein thioesterase 2
PRKX protein kinase, X-linked
PTPRE protein tyrosine phosphatase, receptor type, E
RAB23 RAB23, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RPS17P5 ribosomal protein S17 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCRIB scribbled planar cell polarity protein
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIK1 salt-inducible kinase 1
SKI SKI proto-oncogene
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SNHG20 small nucleolar RNA host gene 20
SNX16 sorting nexin 16
SNX24 sorting nexin 24
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TMEM120B transmembrane protein 120B
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTF2 transcription termination factor, RNA polymerase II
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WDR82 WD repeat domain 82
YEATS4 YEATS domain containing 4
ZBED1 zinc finger, BED-type containing 1
ZBTB44 zinc finger and BTB domain containing 44
ZNF268 zinc finger protein 268
ZNF329 zinc finger protein 329
ZNF446 zinc finger protein 446