alpha-ergocryptine-3900 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the alpha-ergocryptine-3900 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
AGFG1 ArfGAP with FG repeats 1
ATP10B ATPase, class V, type 10B
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
C3ORF18 chromosome 3 open reading frame 18
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAPN10 calpain 10
CARD14 caspase recruitment domain family, member 14
CCL22 chemokine (C-C motif) ligand 22
CCNJL cyclin J-like
CD58 CD58 molecule
CDC42 cell division cycle 42
CEND1 cell cycle exit and neuronal differentiation 1
CHN2 chimerin 2
CNOT2 CCR4-NOT transcription complex, subunit 2
COL16A1 collagen, type XVI, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRMP1 collapsin response mediator protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAXX death-domain associated protein
DFNB31 deafness, autosomal recessive 31
DLC1 DLC1 Rho GTPase activating protein
DNASE1L3 deoxyribonuclease I-like 3
DRD2 dopamine receptor D2
EMC3 ER membrane protein complex subunit 3
ERN2 endoplasmic reticulum to nucleus signaling 2
F11 coagulation factor XI
FAM134B family with sequence similarity 134, member B
FBXO2 F-box protein 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GSK3A glycogen synthase kinase 3 alpha
HBEGF heparin-binding EGF-like growth factor
HDAC6 histone deacetylase 6
HEMK1 HemK methyltransferase family member 1
HR hair growth associated
ICAM1 intercellular adhesion molecule 1
INHBE inhibin, beta E
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LMO1 LIM domain only 1 (rhombotin 1)
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRC15 leucine rich repeat containing 15
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MEF2D myocyte enhancer factor 2D
MMP11 matrix metallopeptidase 11
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MYO9A myosin IXA
NMT2 N-myristoyltransferase 2
NUPR1 nuclear protein, transcriptional regulator, 1
OLFM1 olfactomedin 1
PARVA parvin, alpha
PCBP3 poly(rC) binding protein 3
PCDHGB5 protocadherin gamma subfamily B, 5
PCLO piccolo presynaptic cytomatrix protein
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PML promyelocytic leukemia
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRDM10 PR domain containing 10
PRLH prolactin releasing hormone
PRLR prolactin receptor
PRPF18 pre-mRNA processing factor 18
PTK2B protein tyrosine kinase 2 beta
PYHIN1 pyrin and HIN domain family, member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SAG S-antigen; retina and pineal gland (arrestin)
SARM1 sterile alpha and TIR motif containing 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3BP2 SH3-domain binding protein 2
SIRT5 sirtuin 5
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRSF7 serine/arginine-rich splicing factor 7
STAC SH3 and cysteine rich domain
SUN1 Sad1 and UNC84 domain containing 1
TP53I11 tumor protein p53 inducible protein 11
TPP1 tripeptidyl peptidase I
TRIM10 tripartite motif containing 10
TRIM36 tripartite motif containing 36
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL7 tubulin tyrosine ligase-like family member 7
UNC5B unc-5 homolog B (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP22 ubiquitin specific peptidase 22
VAMP4 vesicle-associated membrane protein 4
ZBTB1 zinc finger and BTB domain containing 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP2 ZFP2 zinc finger protein
ZNF862 zinc finger protein 862
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ALOX12 arachidonate 12-lipoxygenase
ALPK1 alpha-kinase 1
AMPD1 adenosine monophosphate deaminase 1
ATP10D ATPase, class V, type 10D
BCO1 beta-carotene oxygenase 1
BMP3 bone morphogenetic protein 3
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C22ORF46 chromosome 22 open reading frame 46
CALML5 calmodulin-like 5
CBX8 chromobox homolog 8
CCDC64 coiled-coil domain containing 64
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLDN1 claudin 1
CLSPN claspin
CNR2 cannabinoid receptor 2 (macrophage)
CRIP1 cysteine-rich protein 1 (intestinal)
CTIF CBP80/20-dependent translation initiation factor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAAM2 dishevelled associated activator of morphogenesis 2
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
DLL3 delta-like 3 (Drosophila)
DOC2A double C2-like domains, alpha
ETV6 ets variant 6
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FAT4 FAT atypical cadherin 4
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
FOXI1 forkhead box I1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GFI1 growth factor independent 1 transcription repressor
GMPR guanosine monophosphate reductase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPNMB glycoprotein (transmembrane) nmb
GPR143 G protein-coupled receptor 143
GPR87 G protein-coupled receptor 87
GRAMD1C GRAM domain containing 1C
HIST1H2AL histone cluster 1, H2al
HMOX1 heme oxygenase 1
HOXC4 homeobox C4
HOXC8 homeobox C8
HSF4 heat shock transcription factor 4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IBSP integrin-binding sialoprotein
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITM2C integral membrane protein 2C
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KLK8 kallikrein-related peptidase 8
LGALS4 lectin, galactoside-binding, soluble, 4
LIF leukemia inhibitory factor
MAST3 microtubule associated serine/threonine kinase 3
MFGE8 milk fat globule-EGF factor 8 protein
MUC3A mucin 3A, cell surface associated
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NPPA natriuretic peptide A
ONECUT2 one cut homeobox 2
OXTR oxytocin receptor
PICK1 protein interacting with PRKCA 1
PITX2 paired-like homeodomain 2
POU4F2 POU class 4 homeobox 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RIBC2 RIB43A domain with coiled-coils 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCARA3 scavenger receptor class A, member 3
SCGB2A2 secretoglobin, family 2A, member 2
SECTM1 secreted and transmembrane 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOAT2 sterol O-acyltransferase 2
SPON2 spondin 2, extracellular matrix protein
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
SUN2 Sad1 and UNC84 domain containing 2
SYNC syncoilin, intermediate filament protein
TAOK1 TAO kinase 1
TCP10 t-complex 10
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
THRAP3 thyroid hormone receptor associated protein 3
THRB thyroid hormone receptor, beta
TSC22D4 TSC22 domain family, member 4
USP36 ubiquitin specific peptidase 36
VIPR1 vasoactive intestinal peptide receptor 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP37 ZFP37 zinc finger protein
ZNF205 zinc finger protein 205
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2