alpha-ergocryptine-3817 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the alpha-ergocryptine-3817 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
APAF1 apoptotic peptidase activating factor 1
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATP10A ATPase, class V, type 10A
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BST1 bone marrow stromal cell antigen 1
C2ORF72 chromosome 2 open reading frame 72
CA5B carbonic anhydrase VB, mitochondrial
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CCDC121 coiled-coil domain containing 121
CCDC177 coiled-coil domain containing 177
CCL20 chemokine (C-C motif) ligand 20
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEND1 cell cycle exit and neuronal differentiation 1
CHI3L2 chitinase 3-like 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CREBZF CREB/ATF bZIP transcription factor
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMC1 DNA meiotic recombinase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNB dystrobrevin, beta
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFR3B EFR3 homolog B (S. cerevisiae)
EPS8L1 EPS8-like 1
ETV1 ets variant 1
FAM182B family with sequence similarity 182, member B
FLJ11710 uncharacterized protein FLJ11710
FTCD formimidoyltransferase cyclodeaminase
FZD10 frizzled class receptor 10
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR182 G protein-coupled receptor 182
GRIP2 glutamate receptor interacting protein 2
GRM2 glutamate receptor, metabotropic 2
HAND1 heart and neural crest derivatives expressed 1
HDAC6 histone deacetylase 6
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
HHLA1 HERV-H LTR-associating 1
HIST1H3E histone cluster 1, H3e
HOXB3 homeobox B3
IGHA1 immunoglobulin heavy constant alpha 1
JUND jun D proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0485 uncharacterized LOC57235
KIF1C kinesin family member 1C
KLHL18 kelch-like family member 18
LAMA4 laminin, alpha 4
LRRN2 leucine rich repeat neuronal 2
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBNL2 muscleblind-like splicing regulator 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MOBP myelin-associated oligodendrocyte basic protein
MPZ myelin protein zero
MYBPC3 myosin binding protein C, cardiac
NF1 neurofibromin 1
NIN ninein (GSK3B interacting protein)
NPTX1 neuronal pentraxin I
NRCAM neuronal cell adhesion molecule
NRXN3 neurexin 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAX8 paired box 8
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE2A phosphodiesterase 2A, cGMP-stimulated
PIPOX pipecolic acid oxidase
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRSS53 protease, serine, 53
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB40A RAB40A, member RAS oncogene family
RGS10 regulator of G-protein signaling 10
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SHOX2 short stature homeobox 2
SIRPA signal-regulatory protein alpha
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SNED1 sushi, nidogen and EGF-like domains 1
SOX21 SRY (sex determining region Y)-box 21
SRSF5 serine/arginine-rich splicing factor 5
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TEX13A testis expressed 13A
TGFBR1 transforming growth factor, beta receptor 1
THAP3 THAP domain containing, apoptosis associated protein 3
TM4SF4 transmembrane 4 L six family member 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP73-AS1 TP73 antisense RNA 1
TPSAB1 tryptase alpha/beta 1
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP24 Rho GTPase activating protein 24
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BATF3 basic leucine zipper transcription factor, ATF-like 3
BDKRB1 bradykinin receptor B1
C1ORF21 chromosome 1 open reading frame 21
C1ORF54 chromosome 1 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDKL3 cyclin-dependent kinase-like 3
CHMP6 charged multivesicular body protein 6
CLSTN3 calsyntenin 3
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORT cortistatin
CPNE7 copine VII
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYB5R2 cytochrome b5 reductase 2
DENND2D DENN/MADD domain containing 2D
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNASE1L3 deoxyribonuclease I-like 3
DOK5 docking protein 5
EGFL7 EGF-like-domain, multiple 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC6B exocyst complex component 6B
FKRP fukutin related protein
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAS8 growth arrest-specific 8
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPNMB glycoprotein (transmembrane) nmb
GPR21 G protein-coupled receptor 21
GPR75 G protein-coupled receptor 75
HIST1H2AK histone cluster 1, H2ak
HSPA1L heat shock 70kDa protein 1-like
IL24 interleukin 24
IL6 interleukin 6
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCTD17 potassium channel tetramerization domain containing 17
KLHL25 kelch-like family member 25
KRT4 keratin 4, type II
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LYPD3 LY6/PLAUR domain containing 3
MAP3K7CL MAP3K7 C-terminal like
MEFV Mediterranean fever
MRPS18C mitochondrial ribosomal protein S18C
NR1H4 nuclear receptor subfamily 1, group H, member 4
NXPH4 neurexophilin 4
OCA2 oculocutaneous albinism II
OGDHL oxoglutarate dehydrogenase-like
OLFML2B olfactomedin-like 2B
PACS1 phosphofurin acidic cluster sorting protein 1
PGLYRP4 peptidoglycan recognition protein 4
PICK1 protein interacting with PRKCA 1
PIP prolactin-induced protein
PLAC8 placenta-specific 8
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRAF2 PRA1 domain family, member 2
PRB3 proline-rich protein BstNI subfamily 3
PRF1 perforin 1 (pore forming protein)
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RNF39 ring finger protein 39
RNF43 ring finger protein 43
RUNX1-IT1 RUNX1 intronic transcript 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCML2 sex comb on midleg-like 2 (Drosophila)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SPANXC SPANX family, member C
SSTR4 somatostatin receptor 4
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STXBP5L syntaxin binding protein 5-like
TFCP2L1 transcription factor CP2-like 1
TMEM180 transmembrane protein 180
TMEM74B transmembrane protein 74B
TNS4 tensin 4
TRAC T cell receptor alpha constant
TUBA4B tubulin, alpha 4b
TXK TXK tyrosine kinase
UNC119 unc-119 homolog (C. elegans)
USP20 ubiquitin specific peptidase 20
VWA1 von Willebrand factor A domain containing 1
ZBTB33 zinc finger and BTB domain containing 33
ZMAT5 zinc finger, matrin-type 5
ZNF205 zinc finger protein 205
ZNF234 zinc finger protein 234
ZNF552 zinc finger protein 552
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747