alpha-ergocryptine-2572 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the alpha-ergocryptine-2572 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHCYL2 adenosylhomocysteinase-like 2
AOAH acyloxyacyl hydrolase (neutrophil)
ARG1 arginase 1
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATP10B ATPase, class V, type 10B
ATP9B ATPase, class II, type 9B
AXL AXL receptor tyrosine kinase
BPI bactericidal/permeability-increasing protein
CAV1 caveolin 1, caveolae protein, 22kDa
CCL20 chemokine (C-C motif) ligand 20
CD38 CD38 molecule
CD86 CD86 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CREM cAMP responsive element modulator
CRMP1 collapsin response mediator protein 1
DAGLA diacylglycerol lipase, alpha
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK4 dedicator of cytokinesis 4
DPY19L1 dpy-19-like 1 (C. elegans)
DUSP4 dual specificity phosphatase 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNB2 ephrin-B2
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FMNL1 formin-like 1
FTH1 ferritin, heavy polypeptide 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAS2L1 growth arrest-specific 2 like 1
GLI3 GLI family zinc finger 3
GPR19 G protein-coupled receptor 19
GPX2 glutathione peroxidase 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2BC histone cluster 1, H2bc
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA10 homeobox A10
ICOSLG inducible T-cell co-stimulator ligand
KIDINS220 kinase D-interacting substrate, 220kDa
KLF3 Kruppel-like factor 3 (basic)
KLK1 kallikrein 1
KYNU kynureninase
LAMA4 laminin, alpha 4
LAT2 linker for activation of T cells family, member 2
LMF2 lipase maturation factor 2
MAPK8 mitogen-activated protein kinase 8
MCAM melanoma cell adhesion molecule
MCTP2 multiple C2 domains, transmembrane 2
MED25 mediator complex subunit 25
MEF2C myocyte enhancer factor 2C
MFAP3L microfibrillar-associated protein 3-like
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRC2 mannose receptor, C type 2
MST1 macrophage stimulating 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NPC1 Niemann-Pick disease, type C1
NRG1 neuregulin 1
NUP54 nucleoporin 54kDa
PADI2 peptidyl arginine deiminase, type II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4B phosphodiesterase 4B, cAMP-specific
PHF20L1 PHD finger protein 20-like 1
PLSCR1 phospholipid scramblase 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRB1 proline-rich protein BstNI subfamily 1
PROL1 proline rich, lacrimal 1
PTK2 protein tyrosine kinase 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RECQL5 RecQ protein-like 5
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC2 syndecan 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRPB1 signal-regulatory protein beta 1
SLC16A4 solute carrier family 16, member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLITRK5 SLIT and NTRK-like family, member 5
SNW1 SNW domain containing 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SZT2 seizure threshold 2 homolog (mouse)
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
THBS1 thrombospondin 1
TMC6 transmembrane channel-like 6
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRA T cell receptor alpha locus
TSC2 tuberous sclerosis 2
TTC30A tetratricopeptide repeat domain 30A
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VEGFA vascular endothelial growth factor A
ZFHX3 zinc finger homeobox 3
ZNF155 zinc finger protein 155
ZNF177 zinc finger protein 177
ZNF215 zinc finger protein 215
ZNF467 zinc finger protein 467
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AIM2 absent in melanoma 2
ART1 ADP-ribosyltransferase 1
AVPI1 arginine vasopressin-induced 1
BMP15 bone morphogenetic protein 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDON cell adhesion associated, oncogene regulated
CFAP45 cilia and flagella associated protein 45
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDN dendrin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENO3 enolase 3 (beta, muscle)
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM102A family with sequence similarity 102, member A
FAM163A family with sequence similarity 163, member A
FAM184A family with sequence similarity 184, member A
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
FKBP9 FK506 binding protein 9, 63 kDa
FOXO4 forkhead box O4
FRMPD1 FERM and PDZ domain containing 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIF gastric intrinsic factor (vitamin B synthesis)
GIPR gastric inhibitory polypeptide receptor
GSN-AS1 GSN antisense RNA 1
GSTT1 glutathione S-transferase theta 1
HIST1H3I histone cluster 1, H3i
HLA-DMB major histocompatibility complex, class II, DM beta
HOXB9 homeobox B9
HOXC8 homeobox C8
HRH2 histamine receptor H2
IFNA17 interferon, alpha 17
IGFBP4 insulin-like growth factor binding protein 4
IGKV3-20 immunoglobulin kappa variable 3-20
IQSEC2 IQ motif and Sec7 domain 2
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LOC257152 uncharacterized LOC257152
LRRC49 leucine rich repeat containing 49
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGLL monoglyceride lipase
MKRN3 makorin ring finger protein 3
MRAS muscle RAS oncogene homolog
MRPS18C mitochondrial ribosomal protein S18C
MSC musculin
MTRF1 mitochondrial translational release factor 1
MYO1E myosin IE
NCKAP1L NCK-associated protein 1-like
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRAP nebulin-related anchoring protein
PBOV1 prostate and breast cancer overexpressed 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PER3 period circadian clock 3
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMEL premelanosome protein
PRR7 proline rich 7 (synaptic)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
QTRT1 queuine tRNA-ribosyltransferase 1
REPS2 RALBP1 associated Eps domain containing 2
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF25 ring finger protein 25
SHPK sedoheptulokinase
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC12A8 solute carrier family 12, member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPEF1 sperm flagellar 1
STBD1 starch binding domain 1
STMN4 stathmin-like 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT13 synaptotagmin XIII
TCTN2 tectonic family member 2
TEC tec protein tyrosine kinase
TIAM2 T-cell lymphoma invasion and metastasis 2
TNS2 tensin 2
UPK3A uroplakin 3A
VWA1 von Willebrand factor A domain containing 1
WASF3 WAS protein family, member 3
WNT1 wingless-type MMTV integration site family, member 1
ZBTB25 zinc finger and BTB domain containing 25
ZNF280A zinc finger protein 280A