alimemazine-7235 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the alimemazine-7235 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADAM22 ADAM metallopeptidase domain 22
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADTRP androgen-dependent TFPI-regulating protein
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP8A bone morphogenetic protein 8a
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCL11 chemokine (C-C motif) ligand 11
CCNG2 cyclin G2
CD6 CD6 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CREBZF CREB/ATF bZIP transcription factor
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDIT3 DNA-damage-inducible transcript 3
DKFZP434C153 DKFZP434C153 protein
DOK4 docking protein 4
ELOVL5 ELOVL fatty acid elongase 5
EXOSC1 exosome component 1
FAM214B family with sequence similarity 214, member B
FBXO42 F-box protein 42
GPR137 G protein-coupled receptor 137
GRK5 G protein-coupled receptor kinase 5
GSTP1 glutathione S-transferase pi 1
HIST1H2AJ histone cluster 1, H2aj
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HOXB3 homeobox B3
HPS1 Hermansky-Pudlak syndrome 1
IDS iduronate 2-sulfatase
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLJ3 immunoglobulin lambda joining 3
IGSF6 immunoglobulin superfamily, member 6
KDM6A lysine (K)-specific demethylase 6A
KIAA1109 KIAA1109
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL24 kelch-like family member 24
KYNU kynureninase
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAN1A1 mannosidase, alpha, class 1A, member 1
MTAP methylthioadenosine phosphorylase
MTERF4 mitochondrial transcription termination factor 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF1 neurofibromin 1
NLE1 notchless homolog 1 (Drosophila)
NPR3 natriuretic peptide receptor 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
ORAI2 ORAI calcium release-activated calcium modulator 2
PBOV1 prostate and breast cancer overexpressed 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRB1 proline-rich protein BstNI subfamily 1
PTCRA pre T-cell antigen receptor alpha
RCAN3 RCAN family member 3
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS12 regulator of G-protein signaling 12
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF43 ring finger protein 43
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SOS2 son of sevenless homolog 2 (Drosophila)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TMEM19 transmembrane protein 19
TMEM212 transmembrane protein 212
TMEM259 transmembrane protein 259
TNK2 tyrosine kinase, non-receptor, 2
TRIM3 tripartite motif containing 3
TTC28 tetratricopeptide repeat domain 28
USP34 ubiquitin specific peptidase 34
VIPR1 vasoactive intestinal peptide receptor 1
VPRBP Vpr (HIV-1) binding protein
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YY2 YY2 transcription factor
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF329 zinc finger protein 329

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRE5 adhesion G protein-coupled receptor E5
AFG3L2 AFG3-like AAA ATPase 2
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB2 arrestin, beta 2
ASB9 ankyrin repeat and SOCS box containing 9
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
CBX7 chromobox homolog 7
CCNJ cyclin J
CDON cell adhesion associated, oncogene regulated
CDR2L cerebellar degeneration-related protein 2-like
CEP72 centrosomal protein 72kDa
CFAP69 cilia and flagella associated protein 69
CIC capicua transcriptional repressor
CLCF1 cardiotrophin-like cytokine factor 1
CLCN5 chloride channel, voltage-sensitive 5
CLDN15 claudin 15
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF17 DDB1 and CUL4 associated factor 17
DNMBP dynamin binding protein
ELOVL4 ELOVL fatty acid elongase 4
EPPK1 epiplakin 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXD3 exonuclease 3'-5' domain containing 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM53B family with sequence similarity 53, member B
FBXO2 F-box protein 2
FER fer (fps/fes related) tyrosine kinase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KLC2 kinesin light chain 2
LIN7B lin-7 homolog B (C. elegans)
LINS lines homolog (Drosophila)
LOC730101 uncharacterized LOC730101
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAN2C1 mannosidase, alpha, class 2C, member 1
MANBA mannosidase, beta A, lysosomal
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARC1 mitochondrial amidoxime reducing component 1
METTL2B methyltransferase like 2B
MFSD12 major facilitator superfamily domain containing 12
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MYO1E myosin IE
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFS1 NFS1 cysteine desulfurase
NLK nemo-like kinase
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PAQR3 progestin and adipoQ receptor family member III
PCDHGB5 protocadherin gamma subfamily B, 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS22 protease, serine, 22
PTK6 protein tyrosine kinase 6
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF2 ring finger protein 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP1 ribosomal RNA processing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCAI suppressor of cancer cell invasion
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNX15 sorting nexin 15
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TIGD6 tigger transposable element derived 6
TMEM2 transmembrane protein 2
TMEM51 transmembrane protein 51
TNK1 tyrosine kinase, non-receptor, 1
TOM1 target of myb1 (chicken)
TRAF2 TNF receptor-associated factor 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
WWC2 WW and C2 domain containing 2
ZFP30 ZFP30 zinc finger protein
ZMYM1 zinc finger, MYM-type 1
ZNF141 zinc finger protein 141
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747