alcoholism Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)|Disorders related to or resulting from abuse or mis-use of alcohol. (Experimental Factor Ontology, EFO_0003829)
Similar Terms
Downloads & Tools

Genes

72 genes co-occuring with the biological term alcoholism in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKK1 ankyrin repeat and kinase domain containing 1
BDNF brain-derived neurotrophic factor
CALCA calcitonin-related polypeptide alpha
CARTPT CART prepropeptide
CHRM2 cholinergic receptor, muscarinic 2
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
COMT catechol-O-methyltransferase
CRH corticotropin releasing hormone
CRHBP corticotropin releasing hormone binding protein
CRHR1 corticotropin releasing hormone receptor 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAAH fatty acid amide hydrolase
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GAL galanin/GMAP prepropeptide
GALR1 galanin receptor 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GGT2 gamma-glutamyltransferase 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM3 glutamate receptor, metabotropic 3
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
HFE hemochromatosis
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IL10 interleukin 10
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
MAOA monoamine oxidase A
MGLL monoglyceride lipase
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPY neuropeptide Y
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRD1 nardilysin (N-arginine dibasic convertase)
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin
PNOC prepronociceptin
PPARA peroxisome proliferator-activated receptor alpha
PRNP prion protein
PTPRB protein tyrosine phosphatase, receptor type, B
RXRB retinoid X receptor, beta
SGCE sarcoglycan, epsilon
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TPH2 tryptophan hydroxylase 2