alcohol Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group chemdependency (Genetic Association Database)
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Genes

65 genes associated with the disease alcohol in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKK1 ankyrin repeat and kinase domain containing 1
AR androgen receptor
BDNF brain-derived neurotrophic factor
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
FABP2 fatty acid binding protein 2, intestinal
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATAD2A GATA zinc finger domain containing 2A
GCLC glutamate-cysteine ligase, catalytic subunit
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HMOX1 heme oxygenase 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
LIPC lipase, hepatic
LPL lipoprotein lipase
MAOA monoamine oxidase A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MT-ND2 MTND2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTTP microsomal triglyceride transfer protein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAM1 neural cell adhesion molecule 1
NOS2 nitric oxide synthase 2, inducible
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
OPRM1 opioid receptor, mu 1
PEMT phosphatidylethanolamine N-methyltransferase
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PNMT phenylethanolamine N-methyltransferase
PNPLA3 patatin-like phospholipase domain containing 3
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRSS1 protease, serine, 1 (trypsin 1)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOD2 superoxide dismutase 2, mitochondrial
SPINK1 serine peptidase inhibitor, Kazal type 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TTC12 tetratricopeptide repeat domain 12