aggressive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

806 genes co-occuring with the biological term aggressive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD11 abhydrolase domain containing 11
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ACKR3 atypical chemokine receptor 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTA2 actin, alpha 2, smooth muscle, aorta
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AFP alpha-fetoprotein
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPS alkylglycerone phosphate synthase
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHI1 Abelson helper integration site 1
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AIP aryl hydrocarbon receptor interacting protein
AKAP13 A kinase (PRKA) anchor protein 13
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
AMACR alpha-methylacyl-CoA racemase
AMD1 adenosylmethionine decarboxylase 1
AMH anti-Mullerian hormone
ANGPT2 angiopoietin 2
ANPEP alanyl (membrane) aminopeptidase
ANTXR1 anthrax toxin receptor 1
ANXA2 annexin A2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
APLN apelin
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID1A AT rich interactive domain 1A (SWI-like)
ATAD2 ATPase family, AAA domain containing 2
ATM ATM serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
AURKA aurora kinase A
AURKB aurora kinase B
AXIN1 axin 1
B3GAT1 beta-1,3-glucuronyltransferase 1
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BARD1 BRCA1 associated RING domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BGN biglycan
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C8ORF4 chromosome 8 open reading frame 4
C9ORF72 chromosome 9 open reading frame 72
CA12 carbonic anhydrase XII
CA9 carbonic anhydrase IX
CADM1 cell adhesion molecule 1
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPN3 calpain 3, (p94)
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD14 CD14 molecule
CD151 CD151 molecule (Raph blood group)
CD163 CD163 molecule
CD22 CD22 molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CD69 CD69 molecule
CD7 CD7 molecule
CDC20 cell division cycle 20
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK20 cyclin-dependent kinase 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGB chorionic gonadotropin, beta polypeptide
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHKA choline kinase alpha
CKMT1A creatine kinase, mitochondrial 1A
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CLDN3 claudin 3
CLDN4 claudin 4
CLDN5 claudin 5
CLDN7 claudin 7
CLU clusterin
COMT catechol-O-methyltransferase
COPS5 COP9 signalosome subunit 5
CPA4 carboxypeptidase A4
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CRHR1 corticotropin releasing hormone receptor 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRP C-reactive protein, pentraxin-related
CRTC1 CREB regulated transcription coactivator 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF1 colony stimulating factor 1 (macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTGF connective tissue growth factor
CTHRC1 collagen triple helix repeat containing 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSC cathepsin C
CUL3 cullin 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYBA cytochrome b-245, alpha polypeptide
CYLD cylindromatosis (turban tumor syndrome)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2IP DAB2 interacting protein
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK1 death-associated protein kinase 1
DEFB1 defensin, beta 1
DEFB4A defensin, beta 4A
DGKA diacylglycerol kinase, alpha 80kDa
DHCR7 7-dehydrocholesterol reductase
DIAPH3 diaphanous-related formin 3
DICER1 dicer 1, ribonuclease type III
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DMP1 dentin matrix acidic phosphoprotein 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPYSL5 dihydropyrimidinase-like 5
DRD4 dopamine receptor D4
DYX1C1 dyslexia susceptibility 1 candidate 1
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EBI3 Epstein-Barr virus induced 3
ECT2 epithelial cell transforming 2
EDN1 endothelin 1
EDNRA endothelin receptor type A
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ELAC2 elaC ribonuclease Z 2
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
EML4 echinoderm microtubule associated protein like 4
ENO1 enolase 1, (alpha)
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
EPHA5 EPH receptor A5
EPHB6 EPH receptor B6
EPOR erythropoietin receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ERAS ES cell expressed Ras
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESD esterase D
ESM1 endothelial cell-specific molecule 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F11R F11 receptor
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FABP4 fatty acid binding protein 4, adipocyte
FADD Fas (TNFRSF6)-associated via death domain
FADS2 fatty acid desaturase 2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
FHL2 four and a half LIM domains 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FKBP5 FK506 binding protein 5
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FOXA2 forkhead box A2
FOXC2 forkhead box C2
FOXE1 forkhead box E1
FOXM1 forkhead box M1
FOXN3 forkhead box N3
FOXQ1 forkhead box Q1
FPGS folylpolyglutamate synthase
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FSCN1 fascin actin-bundling protein 1
FUS FUS RNA binding protein
FXYD5 FXYD domain containing ion transport regulator 5
FZD6 frizzled class receptor 6
GAB1 GRB2-associated binding protein 1
GANAB glucosidase, alpha; neutral AB
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GATA5 GATA binding protein 5
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDF1 growth differentiation factor 1
GDF15 growth differentiation factor 15
GDF9 growth differentiation factor 9
GINS2 GINS complex subunit 2 (Psf2 homolog)
GJB2 gap junction protein, beta 2, 26kDa
GLDC glycine dehydrogenase (decarboxylating)
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GMNN geminin, DNA replication inhibitor
GOLM1 golgi membrane protein 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPC3 glypican 3
GPER1 G protein-coupled estrogen receptor 1
GPI glucose-6-phosphate isomerase
GPNMB glycoprotein (transmembrane) nmb
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAS2 hyaluronan synthase 2
HBA1 hemoglobin, alpha 1
HCRTR1 hypocretin (orexin) receptor 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HES1 hes family bHLH transcription factor 1
HES6 hes family bHLH transcription factor 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST4H4 histone cluster 4, H4
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOTAIR HOX transcript antisense RNA
HOXA1 homeobox A1
HOXB13 homeobox B13
HOXB7 homeobox B7
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL12A interleukin 12A
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21R interleukin 21 receptor
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
ILK integrin-linked kinase
ING3 inhibitor of growth family, member 3
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
JAG1 jagged 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KAT5 K(lysine) acetyltransferase 5
KDM1A lysine (K)-specific demethylase 1A
KDR kinase insert domain receptor
KIAA1524 KIAA1524
KIF14 kinesin family member 14
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLK11 kallikrein-related peptidase 11
KLK14 kallikrein-related peptidase 14
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KLK6 kallikrein-related peptidase 6
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
L1CAM L1 cell adhesion molecule
LAMC2 laminin, gamma 2
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LBH limb bud and heart development
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX1 LIM homeobox 1
LIMK1 LIM domain kinase 1
LMNA lamin A/C
LMO4 LIM domain only 4
LMTK3 lemur tyrosine kinase 3
LOXL2 lysyl oxidase-like 2
LOXL4 lysyl oxidase-like 4
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTB4R2 leukotriene B4 receptor 2
LTBP1 latent transforming growth factor beta binding protein 1
LTF lactotransferrin
MALT1 MALT1 paracaspase
MAML2 mastermind-like 2 (Drosophila)
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MATN2 matrilin 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
MCM5 minichromosome maintenance complex component 5
MCPH1 microcephalin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MED1 mediator complex subunit 1
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MGMT O-6-methylguanine-DNA methyltransferase
MIR146B microRNA 146b
MIR148A microRNA 148a
MIR155 microRNA 155
MIR15A microRNA 15a
MIR16-1 microRNA 16-1
MIR17 microRNA 17
MIR181B1 microRNA 181b-1
MIR182 microRNA 182
MIR187 microRNA 187
MIR190A microRNA 190a
MIR191 microRNA 191
MIR200A microRNA 200a
MIR200B microRNA 200b
MIR200C microRNA 200c
MIR205 microRNA 205
MIR21 microRNA 21
MIR210 microRNA 210
MIR221 microRNA 221
MIR222 microRNA 222
MIR223 microRNA 223
MIR224 microRNA 224
MIR26A1 microRNA 26a-1
MIR29A microRNA 29a
MIR29B1 microRNA 29b-1
MIR29C microRNA 29c
MIR31 microRNA 31
MIR34A microRNA 34a
MIR372 microRNA 372
MIR425 microRNA 425
MIR497 microRNA 497
MIR9-1 microRNA 9-1
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP26 matrix metallopeptidase 26
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSI1 musashi RNA-binding protein 1
MSLN mesothelin
MSMB microseminoprotein, beta-
MSRA methionine sulfoxide reductase A
MST1R macrophage stimulating 1 receptor
MT1A metallothionein 1A
MTA1 metastasis associated 1
MTDH metadherin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC15 mucin 15, cell surface associated
MUC16 mucin 16, cell surface associated
MUC7 mucin 7, secreted
MUM1 melanoma associated antigen (mutated) 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBAT1 neuroblastoma associated transcript 1
NBN nibrin
NCAM1 neural cell adhesion molecule 1
NCEH1 neutral cholesterol ester hydrolase 1
NCOA3 nuclear receptor coactivator 3
NCR1 natural cytotoxicity triggering receptor 1
NDRG1 N-myc downstream regulated 1
NES nestin
NET1 neuroepithelial cell transforming 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX3-1 NK3 homeobox 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NODAL nodal growth differentiation factor
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP1 neuropilin 1
NRP2 neuropilin 2
NRTN neurturin
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NTSR1 neurotensin receptor 1 (high affinity)
NUAK1 NUAK family, SNF1-like kinase, 1
NUPR1 nuclear protein, transcriptional regulator, 1
NUTM1 NUT midline carcinoma, family member 1
ODC1 ornithine decarboxylase 1
OGG1 8-oxoguanine DNA glycosylase
OPTN optineurin
OSM oncostatin M
OXTR oxytocin receptor
PACRG PARK2 co-regulated
PAGE4 P antigen family, member 4 (prostate associated)
PALB2 partner and localizer of BRCA2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PAWR PRKC, apoptosis, WT1, regulator
PAX5 paired box 5
PBRM1 polybromo 1
PBX1 pre-B-cell leukemia homeobox 1
PCA3 prostate cancer associated 3 (non-protein coding)
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDCD7 programmed cell death 7
PDIA3 protein disulfide isomerase family A, member 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPN podoplanin
PDX1 pancreatic and duodenal homeobox 1
PEBP1 phosphatidylethanolamine binding protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITX3 paired-like homeodomain 3
PIWIL1 piwi-like RNA-mediated gene silencing 1
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKP1 plakophilin 1
PKP3 plakophilin 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCB2 phospholipase C, beta 2
PLK1 polo-like kinase 1
PLXNA2 plexin A2
PNKD paroxysmal nonkinesigenic dyskinesia
POLB polymerase (DNA directed), beta
PON1 paraoxonase 1
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
PRKD1 protein kinase D1
PRMT5 protein arginine methyltransferase 5
PROM1 prominin 1
PROS1 protein S (alpha)
PROX1 prospero homeobox 1
PSD4 pleckstrin and Sec7 domain containing 4
PSEN1 presenilin 1
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTOV1 prostate tumor overexpressed 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTTG1 pituitary tumor-transforming 1
PVT1 Pvt1 oncogene (non-protein coding)
PXN paxillin
PYCARD PYD and CARD domain containing
RAB5A RAB5A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD21 RAD21 homolog (S. pombe)
RAN RAN, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBP5 retinol binding protein 5, cellular
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REG4 regenerating islet-derived family, member 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RET ret proto-oncogene
RHOA ras homolog family member A
RHOC ras homolog family member C
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPSA ribosomal protein SA
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RUNX1 runt-related transcription factor 1
S100A10 S100 calcium binding protein A10
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SALL4 spalt-like transcription factor 4
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCRIB scribbled planar cell polarity protein
SDC1 syndecan 1
SDC4 syndecan 4
SELE selectin E
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHH sonic hedgehog
SIAH2 siah E3 ubiquitin protein ligase 2
SIPA1 signal-induced proliferation-associated 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF7 SLAM family member 7
SLC16A4 solute carrier family 16, member 4
SLC22A17 solute carrier family 22, member 17
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMYD3 SET and MYND domain containing 3
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS6 suppressor of cytokine signaling 6
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOX11 SRY (sex determining region Y)-box 11
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPDEF SAM pointed domain containing ETS transcription factor
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SPTA1 spectrin, alpha, erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SSTR1 somatostatin receptor 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STIP1 stress-induced phosphoprotein 1
STK11 serine/threonine kinase 11
STRN striatin, calmodulin binding protein
STX7 syntaxin 7
TACSTD2 tumor-associated calcium signal transducer 2
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFE3 transcription factor binding to IGHM enhancer 3
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THOC1 THO complex 1
THRA thyroid hormone receptor, alpha
THY1 Thy-1 cell surface antigen
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TKTL1 transketolase-like 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMPRSS2 transmembrane protease, serine 2
TMSB10 thymosin beta 10
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPH1 tryptophan hydroxylase 1
TRD T cell receptor delta locus
TREM1 triggering receptor expressed on myeloid cells 1
TRG T cell receptor gamma locus
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPO translocator protein (18kDa)
TTK TTK protein kinase
TUBB3 tubulin, beta 3 class III
TWIST1 twist family bHLH transcription factor 1
TYMS thymidylate synthetase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UPK3A uroplakin 3A
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
VAV2 vav 2 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VPREB3 pre-B lymphocyte 3
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT1 wingless-type MMTV integration site family, member 1
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XDH xanthine dehydrogenase
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB33 zinc finger and BTB domain containing 33
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZNF132 zinc finger protein 132