agerelated Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

312 genes co-occuring with the biological term agerelated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACE angiotensin I converting enzyme
ACO1 aconitase 1, soluble
ACP1 acid phosphatase 1, soluble
ACP5 acid phosphatase 5, tartrate resistant
ACVRL1 activin A receptor type II-like 1
ADA adenosine deaminase
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AMH anti-Mullerian hormone
AOC3 amine oxidase, copper containing 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOD apolipoprotein D
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARG2 arginase 2
ARMS2 age-related maculopathy susceptibility 2
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BDNF brain-derived neurotrophic factor
BIK BCL2-interacting killer (apoptosis-inducing)
BMP4 bone morphogenetic protein 4
C2 complement component 2
C3 complement component 3
C5 complement component 5
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CANX calnexin
CAT catalase
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL22 chemokine (C-C motif) ligand 22
CCL24 chemokine (C-C motif) ligand 24
CCNA1 cyclin A1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR3 complement factor H-related 3
CFHR5 complement factor H-related 5
CFI complement factor I
CFP complement factor properdin
CHM choroideremia (Rab escort protein 1)
CLPTM1L CLPTM1-like
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COMT catechol-O-methyltransferase
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CRYBB1 crystallin, beta B1
CRYBB2 crystallin, beta B2
CRYGA crystallin, gamma A
CRYGD crystallin, gamma D
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTGF connective tissue growth factor
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DFNA5 deafness, autosomal dominant 5
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
ELN elastin
ELOVL4 ELOVL fatty acid elongase 4
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
ESR1 estrogen receptor 1
EZR ezrin
F3 coagulation factor III (thromboplastin, tissue factor)
F9 coagulation factor IX
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM53B family with sequence similarity 53, member B
FBLN5 fibulin 5
FHL1 four and a half LIM domains 1
FKBPL FK506 binding protein like
FRK fyn-related Src family tyrosine kinase
FTL ferritin, light polypeptide
GADD45A growth arrest and DNA-damage-inducible, alpha
GALK1 galactokinase 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAS6 growth arrest-specific 6
GH1 growth hormone 1
GJA3 gap junction protein, alpha 3, 46kDa
GJA8 gap junction protein, alpha 8, 50kDa
GJB2 gap junction protein, beta 2, 26kDa
GLB1 galactosidase, beta 1
GPX1 glutathione peroxidase 1
GRHL2 grainyhead-like 2 (Drosophila)
GRM7 glutamate receptor, metabotropic 7
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMCN1 hemicentin 1
HMGB2 high mobility group box 2
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HP haptoglobin
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSF4 heat shock transcription factor 4
HTRA1 HtrA serine peptidase 1
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL12A interleukin 12A
IL18 interleukin 18
IL27RA interleukin 27 receptor, alpha
IL33 interleukin 33
IL6 interleukin 6
IQGAP2 IQ motif containing GTPase activating protein 2
IREB2 iron-responsive element binding protein 2
ITGA9 integrin, alpha 9
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KL klotho
KLC1 kinesin light chain 1
KLF5 Kruppel-like factor 5 (intestinal)
LAMP2 lysosomal-associated membrane protein 2
LEP leptin
LIM2 lens intrinsic membrane protein 2, 19kDa
LIPC lipase, hepatic
LMNA lamin A/C
LOXL1 lysyl oxidase-like 1
LPA lipoprotein, Lp(a)
LRP2 low density lipoprotein receptor-related protein 2
LRP6 low density lipoprotein receptor-related protein 6
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MBP myelin basic protein
MC4R melanocortin 4 receptor
MCL1 myeloid cell leukemia 1
MDM1 Mdm1 nuclear protein homolog (mouse)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFGE8 milk fat globule-EGF factor 8 protein
MGMT O-6-methylguanine-DNA methyltransferase
MGST1 microsomal glutathione S-transferase 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MIRLET7B microRNA let-7b
MLH1 mutL homolog 1
MLXIPL MLX interacting protein-like
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUTYH mutY homolog
MVP major vault protein
MYBPC3 myosin binding protein C, cardiac
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NDRG2 NDRG family member 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NPPA natriuretic peptide A
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRG1 neuregulin 1
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OGG1 8-oxoguanine DNA glycosylase
OSBP2 oxysterol binding protein 2
PARK7 parkinson protein 7
PDGFB platelet-derived growth factor beta polypeptide
PER1 period circadian clock 1
PER2 period circadian clock 2
PER3 period circadian clock 3
PINK1 PTEN induced putative kinase 1
PKM pyruvate kinase, muscle
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRNP prion protein
PROK1 prokineticin 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PSEN1 presenilin 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAD51 RAD51 recombinase
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP4 retinoblastoma binding protein 4
RET ret proto-oncogene
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROMO1 reactive oxygen species modulator 1
RORA RAR-related orphan receptor A
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN1A sodium channel, voltage gated, type I alpha subunit
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A12 solute carrier family 16, member 12
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAI1 snail family zinc finger 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
SPP1 secreted phosphoprotein 1
SUCNR1 succinate receptor 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TARDBP TAR DNA binding protein
TDRD7 tudor domain containing 7
TDRP testis development related protein
TEAD4 TEA domain family member 4
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TF transferrin
TFR2 transferrin receptor 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THRA thyroid hormone receptor, alpha
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TJP2 tight junction protein 2
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNMD tenomodulin
TNXB tenascin XB
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TRA2B transformer 2 beta homolog (Drosophila)
TTR transthyretin
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UMOD uromodulin
VCL vinculin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WNT4 wingless-type MMTV integration site family, member 4
WRN Werner syndrome, RecQ helicase-like
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6