ageing Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700). (Gene Ontology, GO_0007568)
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Genes

62 genes co-occuring with the biological term ageing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADRA2B adrenoceptor alpha 2B
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMH anti-Mullerian hormone
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATM ATM serine/threonine kinase
BDNF brain-derived neurotrophic factor
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN2A cyclin-dependent kinase inhibitor 2A
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
COX2
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYR61 cysteine-rich, angiogenic inducer, 61
EGR1 early growth response 1
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
FGF23 fibroblast growth factor 23
FOXM1 forkhead box M1
FOXO1 forkhead box O1
GHRL ghrelin/obestatin prepropeptide
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
IFNA1 interferon, alpha 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
INS insulin
KL klotho
LMNA lamin A/C
MAPK1 mitogen-activated protein kinase 1
MIR181A2 microRNA 181a-2
MIR34A microRNA 34a
MMP10 matrix metallopeptidase 10
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MT2A metallothionein 2A
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NPPB natriuretic peptide B
PAX5 paired box 5
POLG polymerase (DNA directed), gamma
PRNP prion protein
PTPRC protein tyrosine phosphatase, receptor type, C
RARA retinoic acid receptor, alpha
REST RE1-silencing transcription factor
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
TARDBP TAR DNA binding protein
TERC telomerase RNA component
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TP53 tumor protein p53
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VEGFA vascular endothelial growth factor A
WRN Werner syndrome, RecQ helicase-like
XDH xanthine dehydrogenase