adult t-cell lymphoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A cell of a malignancy of mature T lymphocytes with onset in adulthood, believed to be caused by human T-lymphotropic virus 1 and characterized by circulating pleomorphic malignant lymphocytes, skin lesions, lymphadenopathy, hepatosplenomegaly, hypercalcemia, and lytic bone lesions; its course may be subacute or chronic. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001344)
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Genes

181 proteins co-occuring with the tissue adult t-cell lymphoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
HBZ hemoglobin, zeta 2.37103
IL2RA interleukin 2 receptor, alpha 1.69201
IL2 interleukin 2 1.47942
JUND jun D proto-oncogene 1.47101
CD4 CD4 molecule 1.4589
BCL3 B-cell CLL/lymphoma 3 1.23272
BIRC5 baculoviral IAP repeat containing 5 1.16914
ATL2 atlastin GTPase 2 1.14077
PTHLH parathyroid hormone-like hormone 1.13368
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 1.10491
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.07971
BIRC3 baculoviral IAP repeat containing 3 1.07088
CCND2 cyclin D2 1.04401
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.04093
CCL3L1 chemokine (C-C motif) ligand 3-like 1 1.00719
OAT ornithine aminotransferase 0.935341
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.925907
CCDC88C coiled-coil domain containing 88C 0.909666
CD7 CD7 molecule 0.857995
TP53 tumor protein p53 0.793543
JUNB jun B proto-oncogene 0.791044
CDC23 cell division cycle 23 0.772344
BCL2L1 BCL2-like 1 0.765711
BIRC2 baculoviral IAP repeat containing 2 0.76157
ANAPC5 anaphase promoting complex subunit 5 0.757432
CDK6 cyclin-dependent kinase 6 0.745864
RAB5B RAB5B, member RAS oncogene family 0.731442
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.726918
FOXP3 forkhead box P3 0.71501
IL21R interleukin 21 receptor 0.711729
TARS threonyl-tRNA synthetase 0.650966
CNTN2 contactin 2 (axonal) 0.646911
MVP major vault protein 0.63274
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.620217
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.61941
TRIO trio Rho guanine nucleotide exchange factor 0.618603
MSH3 mutS homolog 3 0.612555
IL9 interleukin 9 0.610541
CD52 CD52 molecule 0.592845
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.590437
IL5 interleukin 5 0.588431
CDKL5 cyclin-dependent kinase-like 5 0.578016
CDK4 cyclin-dependent kinase 4 0.57042
HSPA1B heat shock 70kDa protein 1B 0.560449
SELL selectin L 0.553286
TIGAR TP53 induced glycolysis regulatory phosphatase 0.549312
IL4R interleukin 4 receptor 0.547326
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.538802
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.535042
STRBP spermatid perinuclear RNA binding protein 0.531484
IL1A interleukin 1, alpha 0.527534
FAF1 Fas (TNFRSF6) associated factor 1 0.524771
TRAC T cell receptor alpha constant 0.523982
GZMM granzyme M (lymphocyte met-ase 1) 0.522405
HMP19 HMP19 protein 0.520435
FOXN2 forkhead box N2 0.517284
CCL22 chemokine (C-C motif) ligand 22 0.511778
IL2RB interleukin 2 receptor, beta 0.492182
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.488276
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 0.48087
CCND1 cyclin D1 0.474258
B2M beta-2-microglobulin 0.468824
CFB complement factor B 0.468824
POT1 protection of telomeres 1 0.462239
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.461852
IL15 interleukin 15 0.459918
TXN thioredoxin 0.457214
CD3D CD3d molecule, delta (CD3-TCR complex) 0.456442
GNPDA1 glucosamine-6-phosphate deaminase 1 0.452969
NDEL1 nudE neurodevelopment protein 1-like 1 0.450657
CADM1 cell adhesion molecule 1 0.446807
STK25 serine/threonine kinase 25 0.443347
FAS Fas cell surface death receptor 0.434523
CCL3 chemokine (C-C motif) ligand 3 0.427636
RGS1 regulator of G-protein signaling 1 0.415053
CD38 CD38 molecule 0.412771
IL1B interleukin 1, beta 0.410491
LOR loricrin 0.399492
TFRC transferrin receptor 0.391176
IL4 interleukin 4 0.390044
HRAS Harvey rat sarcoma viral oncogene homolog 0.389289
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.388158
GBP1 guanylate binding protein 1, interferon-inducible 0.382131
MIR130B microRNA 130b 0.381191
HDAC8 histone deacetylase 8 0.380627
CDC37 cell division cycle 37 0.378748
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.374993
PDLIM7 PDZ and LIM domain 7 (enigma) 0.371994
CDKN2A cyclin-dependent kinase inhibitor 2A 0.369373
NOG noggin 0.369373
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.366007
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.353712
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.348889
PIAS3 protein inhibitor of activated STAT, 3 0.347038
CCNE2 cyclin E2 0.33965
HSPA1A heat shock 70kDa protein 1A 0.3356
IL17RB interleukin 17 receptor B 0.335233
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.328262
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.326432
WNT5A wingless-type MMTV integration site family, member 5A 0.326067
LEF1 lymphoid enhancer-binding factor 1 0.324239
CDC25C cell division cycle 25C 0.323874
SELE selectin E 0.322779
RARG retinoic acid receptor, gamma 0.317679
CD44 CD44 molecule (Indian blood group) 0.317315
BATF basic leucine zipper transcription factor, ATF-like 0.317133
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.314046
MIR31 microRNA 31 0.31187
PTPRC protein tyrosine phosphatase, receptor type, C 0.310783
ICAM1 intercellular adhesion molecule 1 0.309335
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.307708
CCNB1 cyclin B1 0.299242
PRAME preferentially expressed antigen in melanoma 0.297806
MTAP methylthioadenosine phosphorylase 0.294581
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.285671
ATN1 atrophin 1 0.285316
CNTLN centlein, centrosomal protein 0.283191
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.273696
BAX BCL2-associated X protein 0.271604
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.268828
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.268137
PGM3 phosphoglucomutase 3 0.267791
TERT telomerase reverse transcriptase 0.266413
IFNA1 interferon, alpha 1 0.264696
CCL17 chemokine (C-C motif) ligand 17 0.259929
CCL27 chemokine (C-C motif) ligand 27 0.256234
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.2559
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.250139
PRDM1 PR domain containing 1, with ZNF domain 0.24804
SOX4 SRY (sex determining region Y)-box 4 0.247719
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.247399
CD5 CD5 molecule 0.24676
CDC20 cell division cycle 20 0.24676
MIR223 microRNA 223 0.243918
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.24052
CREB1 cAMP responsive element binding protein 1 0.239307
BBC3 BCL2 binding component 3 0.231482
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.230656
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.225395
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 0.22415
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.223906
SLK STE20-like kinase 0.221291
TIAM1 T-cell lymphoma invasion and metastasis 1 0.219707
HLA-C major histocompatibility complex, class I, C 0.219707
EGR3 early growth response 3 0.21883
MSH6 mutS homolog 6 0.216528
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.214954
HDAC9 histone deacetylase 9 0.213471
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.212413
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.204432
HTRA2 HtrA serine peptidase 2 0.204193
IRF2 interferon regulatory factor 2 0.20222
TCL1A T-cell leukemia/lymphoma 1A 0.201585
CD151 CD151 molecule (Raph blood group) 0.200694
CD58 CD58 molecule 0.200322
MIR145 microRNA 145 0.200092
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.199426
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.199214
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.198771
ITK IL2-inducible T-cell kinase 0.198559
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.19815
TBK1 TANK-binding kinase 1 0.19815
LDB3 LIM domain binding 3 0.197605
STAT2 signal transducer and activator of transcription 2, 113kDa 0.197269
CAV2 caveolin 2 0.196845
RGMA repulsive guidance molecule family member a 0.196767
TGFB2 transforming growth factor, beta 2 0.196619
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.196022
CAV1 caveolin 1, caveolae protein, 22kDa 0.195683
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.19565
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.195385
LCK LCK proto-oncogene, Src family tyrosine kinase 0.194957
CAV3 caveolin 3 0.194849
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.194715
H3F3A H3 histone, family 3A 0.194567
H3F3B H3 histone, family 3B (H3.3B) 0.194567
MMP11 matrix metallopeptidase 11 0.194416
ATF3 activating transcription factor 3 0.193876
F10 coagulation factor X 0.192945
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.190486
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.190251