adrenosterone-6486 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the adrenosterone-6486 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM7 ADAM metallopeptidase domain 7
ADGRF5 adhesion G protein-coupled receptor F5
AGO4 argonaute RISC catalytic component 4
AGTR1 angiotensin II receptor, type 1
ARTN artemin
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BEX4 brain expressed, X-linked 4
BHMT2 betaine--homocysteine S-methyltransferase 2
C10ORF95 chromosome 10 open reading frame 95
CA4 carbonic anhydrase IV
CA5B carbonic anhydrase VB, mitochondrial
CADM4 cell adhesion molecule 4
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD7 CD7 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
COL5A2 collagen, type V, alpha 2
CRH corticotropin releasing hormone
CTGF connective tissue growth factor
CUZD1 CUB and zona pellucida-like domains 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DESI2 desumoylating isopeptidase 2
ERO1LB ERO1-like beta (S. cerevisiae)
FGF18 fibroblast growth factor 18
FSCN3 fascin actin-bundling protein 3, testicular
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLUL glutamate-ammonia ligase
HRG histidine-rich glycoprotein
IL22 interleukin 22
IL2RG interleukin 2 receptor, gamma
INO80D INO80 complex subunit D
INSIG1 insulin induced gene 1
ITGA8 integrin, alpha 8
JAM3 junctional adhesion molecule 3
KIF25 kinesin family member 25
KLK7 kallikrein-related peptidase 7
KRT24 keratin 24, type I
LARP7 La ribonucleoprotein domain family, member 7
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRRC2 leucine rich repeat containing 2
LRRN3 leucine rich repeat neuronal 3
MAOB monoamine oxidase B
MAX MYC associated factor X
MEGF6 multiple EGF-like-domains 6
MRAS muscle RAS oncogene homolog
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEUROD1 neuronal differentiation 1
NOVA2 neuro-oncological ventral antigen 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OSBPL10 oxysterol binding protein-like 10
OVOL2 ovo-like zinc finger 2
PEG3 paternally expressed 3
PKNOX1 PBX/knotted 1 homeobox 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCG1 phospholipase C, gamma 1
PLIN2 perilipin 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPP5C protein phosphatase 5, catalytic subunit
PSD3 pleckstrin and Sec7 domain containing 3
PTAFR platelet-activating factor receptor
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRB protein tyrosine phosphatase, receptor type, B
RARB retinoic acid receptor, beta
RCAN1 regulator of calcineurin 1
RGS3 regulator of G-protein signaling 3
RHEB Ras homolog enriched in brain
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SASH3 SAM and SH3 domain containing 3
SERHL2 serine hydrolase-like 2
SIX1 SIX homeobox 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMR3A submaxillary gland androgen regulated protein 3A
TAC3 tachykinin 3
TBR1 T-box, brain, 1
TBXA2R thromboxane A2 receptor
TCF3 transcription factor 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
THPO thrombopoietin
TMEM209 transmembrane protein 209
TP63 tumor protein p63
TRIM2 tripartite motif containing 2
TSC22D2 TSC22 domain family, member 2
VIPR2 vasoactive intestinal peptide receptor 2
WFDC2 WAP four-disulfide core domain 2
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WSCD1 WSC domain containing 1

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMH anti-Mullerian hormone
ANP32A-IT1 ANP32A intronic transcript 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOD apolipoprotein D
ARHGAP24 Rho GTPase activating protein 24
ARR3 arrestin 3, retinal (X-arrestin)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
CAPG capping protein (actin filament), gelsolin-like
CCDC186 coiled-coil domain containing 186
CCNL2 cyclin L2
CEL carboxyl ester lipase
CENPT centromere protein T
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIR1 corepressor interacting with RBPJ, 1
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CRLF1 cytokine receptor-like factor 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FAM110B family with sequence similarity 110, member B
FAM184A family with sequence similarity 184, member A
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GSTT1 glutathione S-transferase theta 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HIRA histone cell cycle regulator
HIST1H4A histone cluster 1, H4a
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IL15RA interleukin 15 receptor, alpha
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF1 interferon regulatory factor 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0754 KIAA0754
KIAA0894 KIAA0894 protein
KIFC1 kinesin family member C1
KLF11 Kruppel-like factor 11
KLHL28 kelch-like family member 28
KRI1 KRI1 homolog (S. cerevisiae)
LAMA3 laminin, alpha 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC257152 uncharacterized LOC257152
LONP2 lon peptidase 2, peroxisomal
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANBA mannosidase, beta A, lysosomal
MED15 mediator complex subunit 15
MEIS1 Meis homeobox 1
MTERF4 mitochondrial transcription termination factor 4
NPFFR1 neuropeptide FF receptor 1
PADI1 peptidyl arginine deiminase, type I
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDIA3 protein disulfide isomerase family A, member 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAT plasminogen activator, tissue
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PROCR protein C receptor, endothelial
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RBL1 retinoblastoma-like 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIGLEC15 sialic acid binding Ig-like lectin 15
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SRD5A3 steroid 5 alpha-reductase 3
STXBP2 syntaxin binding protein 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
THBS3 thrombospondin 3
TPST2 tyrosylprotein sulfotransferase 2
TRIP10 thyroid hormone receptor interactor 10
TUBG2 tubulin, gamma 2
WDR4 WD repeat domain 4
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF430 zinc finger protein 430
ZNF747 zinc finger protein 747