adiphenine-7279 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the adiphenine-7279 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANAPC5 anaphase promoting complex subunit 5
ARL4D ADP-ribosylation factor-like 4D
ARRB2 arrestin, beta 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP2K BMP2 inducible kinase
BRD4 bromodomain containing 4
BRWD1 bromodomain and WD repeat domain containing 1
BTN3A1 butyrophilin, subfamily 3, member A1
C6ORF120 chromosome 6 open reading frame 120
CABIN1 calcineurin binding protein 1
CALML3 calmodulin-like 3
CEP290 centrosomal protein 290kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CLDN17 claudin 17
COX4I1 cytochrome c oxidase subunit IV isoform 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSO cathepsin O
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DOLPP1 dolichyldiphosphatase 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EIF5B eukaryotic translation initiation factor 5B
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM69A family with sequence similarity 69, member A
FGF1 fibroblast growth factor 1 (acidic)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD7 frizzled class receptor 7
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPR107 G protein-coupled receptor 107
HCFC1 host cell factor C1
HES2 hes family bHLH transcription factor 2
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
INTS6 integrator complex subunit 6
IRF1 interferon regulatory factor 1
IRF6 interferon regulatory factor 6
KCTD20 potassium channel tetramerization domain containing 20
KIF2A kinesin heavy chain member 2A
KLHL20 kelch-like family member 20
LDB1 LIM domain binding 1
LOC100127972 uncharacterized LOC100127972
LOC81691 exonuclease NEF-sp
LRRC41 leucine rich repeat containing 41
LYPD1 LY6/PLAUR domain containing 1
MAPK1 mitogen-activated protein kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MTAP methylthioadenosine phosphorylase
MTUS1 microtubule associated tumor suppressor 1
N4BP2L2 NEDD4 binding protein 2-like 2
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NF2 neurofibromin 2 (merlin)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCOLCE procollagen C-endopeptidase enhancer
PGPEP1 pyroglutamyl-peptidase I
PHACTR2 phosphatase and actin regulator 2
PHTF2 putative homeodomain transcription factor 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPT2 palmitoyl-protein thioesterase 2
PRMT2 protein arginine methyltransferase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB28 RAB28, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFK riboflavin kinase
RNF19B ring finger protein 19B
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SIK2 salt-inducible kinase 2
SKI SKI proto-oncogene
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SMG7 SMG7 nonsense mediated mRNA decay factor
SREBF2 sterol regulatory element binding transcription factor 2
SS18 synovial sarcoma translocation, chromosome 18
STK16 serine/threonine kinase 16
SYT17 synaptotagmin XVII
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TMEM231 transmembrane protein 231
TMEM63A transmembrane protein 63A
TOR1AIP1 torsin A interacting protein 1
TRAK2 trafficking protein, kinesin binding 2
TRIM23 tripartite motif containing 23
TTC38 tetratricopeptide repeat domain 38
UBE3B ubiquitin protein ligase E3B
VAC14 Vac14 homolog (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZNF174 zinc finger protein 174
ZNF200 zinc finger protein 200
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALS2CL ALS2 C-terminal like
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APH1B APH1B gamma secretase subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASB13 ankyrin repeat and SOCS box containing 13
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AUH AU RNA binding protein/enoyl-CoA hydratase
AXIN1 axin 1
C4ORF29 chromosome 4 open reading frame 29
CASZ1 castor zinc finger 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNA1 cyclin A1
CEMIP cell migration inducing protein, hyaluronan binding
CENPC centromere protein C
CENPO centromere protein O
CENPT centromere protein T
CNGB3 cyclic nucleotide gated channel beta 3
CPA4 carboxypeptidase A4
DDN dendrin
DLL3 delta-like 3 (Drosophila)
EDC3 enhancer of mRNA decapping 3
EFCAB2 EF-hand calcium binding domain 2
EFNA1 ephrin-A1
EPHA4 EPH receptor A4
F8 coagulation factor VIII, procoagulant component
FAM131B family with sequence similarity 131, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOXC1 forkhead box C1
FPGS folylpolyglutamate synthase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HMHA1 histocompatibility (minor) HA-1
HOXA4 homeobox A4
HTT huntingtin
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLC2 kinesin light chain 2
LHX6 LIM homeobox 6
LIMD2 LIM domain containing 2
LMBR1L limb development membrane protein 1-like
LPAR4 lysophosphatidic acid receptor 4
LRP3 low density lipoprotein receptor-related protein 3
MAGEA6 melanoma antigen family A6
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFSD11 major facilitator superfamily domain containing 11
MNX1 motor neuron and pancreas homeobox 1
MOB3B MOB kinase activator 3B
MTRF1 mitochondrial translational release factor 1
MUC3B mucin 3B, cell surface associated
NAG18 NAG18 mRNA
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NINJ1 ninjurin 1
NINL ninein-like
NXPH4 neurexophilin 4
PDE8B phosphodiesterase 8B
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB20 RAB20, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RGCC regulator of cell cycle
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGR retinitis pigmentosa GTPase regulator
SAMHD1 SAM domain and HD domain 1
SESN1 sestrin 1
SETD1B SET domain containing 1B
SLC22A18 solute carrier family 22, member 18
SLC25A40 solute carrier family 25, member 40
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNTA1 syntrophin, alpha 1
SOD3 superoxide dismutase 3, extracellular
SPRYD7 SPRY domain containing 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
SYTL2 synaptotagmin-like 2
TESPA1 thymocyte expressed, positive selection associated 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSKU tsukushi, small leucine rich proteoglycan
TTC26 tetratricopeptide repeat domain 26
UNC119 unc-119 homolog (C. elegans)
XPA xeroderma pigmentosum, complementation group A
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF204P zinc finger protein 204, pseudogene
ZNF767P zinc finger family member 767, pseudogene
ZSCAN16 zinc finger and SCAN domain containing 16