adiphenine-7037 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the adiphenine-7037 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADCY3 adenylate cyclase 3
AFAP1 actin filament associated protein 1
AHI1 Abelson helper integration site 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALCAM activated leukocyte cell adhesion molecule
ANKRD26 ankyrin repeat domain 26
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOD apolipoprotein D
APOE apolipoprotein E
APOL2 apolipoprotein L, 2
AXIN1 axin 1
C10ORF95 chromosome 10 open reading frame 95
C2ORF68 chromosome 2 open reading frame 68
CA5BP1 carbonic anhydrase VB pseudogene 1
CASD1 CAS1 domain containing 1
CCDC68 coiled-coil domain containing 68
CD302 CD302 molecule
CHST10 carbohydrate sulfotransferase 10
CXCR4 chemokine (C-X-C motif) receptor 4
CYHR1 cysteine/histidine-rich 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
E2F1 E2F transcription factor 1
EML2 echinoderm microtubule associated protein like 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EXOSC1 exosome component 1
FBXL18 F-box and leucine-rich repeat protein 18
FBXO11 F-box protein 11
FZD7 frizzled class receptor 7
GADD45G growth arrest and DNA-damage-inducible, gamma
GFI1 growth factor independent 1 transcription repressor
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLS2 glutaminase 2 (liver, mitochondrial)
GLUD2 glutamate dehydrogenase 2
GUSBP3 glucuronidase, beta pseudogene 3
HMGA1 high mobility group AT-hook 1
IDI2-AS1 IDI2 antisense RNA 1
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IRF6 interferon regulatory factor 6
JAKMIP2 janus kinase and microtubule interacting protein 2
KIAA1109 KIAA1109
KLF11 Kruppel-like factor 11
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
MAP2K5 mitogen-activated protein kinase kinase 5
MED15 mediator complex subunit 15
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCOA2 nuclear receptor coactivator 2
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NF2 neurofibromin 2 (merlin)
OASL 2'-5'-oligoadenylate synthetase-like
OGFR opioid growth factor receptor
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHA5 protocadherin alpha 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PODXL2 podocalyxin-like 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTK6 protein tyrosine kinase 6
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QKI QKI, KH domain containing, RNA binding
RTEL1 regulator of telomere elongation helicase 1
SETD4 SET domain containing 4
SGSM2 small G protein signaling modulator 2
SH2B3 SH2B adaptor protein 3
SIAH1 siah E3 ubiquitin protein ligase 1
SIX1 SIX homeobox 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOWAHC sosondowah ankyrin repeat domain family member C
SPAST spastin
STEAP4 STEAP family member 4
STK17B serine/threonine kinase 17b
SZT2 seizure threshold 2 homolog (mouse)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBCD tubulin folding cofactor D
TCP11L1 t-complex 11, testis-specific-like 1
TGM2 transglutaminase 2
TMEM51 transmembrane protein 51
TMEM63A transmembrane protein 63A
TRIM10 tripartite motif containing 10
TRIO trio Rho guanine nucleotide exchange factor
TTC33 tetratricopeptide repeat domain 33
ZBED1 zinc finger, BED-type containing 1
ZNF282 zinc finger protein 282
ZNF318 zinc finger protein 318
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD17B abhydrolase domain containing 17B
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARMC6 armadillo repeat containing 6
ARMC7 armadillo repeat containing 7
ASPHD1 aspartate beta-hydroxylase domain containing 1
BAHD1 bromo adjacent homology domain containing 1
BCAS1 breast carcinoma amplified sequence 1
BEX4 brain expressed, X-linked 4
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BMP4 bone morphogenetic protein 4
BTBD7 BTB (POZ) domain containing 7
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDH10 cadherin 10, type 2 (T2-cadherin)
CDON cell adhesion associated, oncogene regulated
CFD complement factor D (adipsin)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNN2 calponin 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNM1 dynamin 1
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
ETAA1 Ewing tumor-associated antigen 1
EXD3 exonuclease 3'-5' domain containing 3
F8 coagulation factor VIII, procoagulant component
FANCE Fanconi anemia, complementation group E
FOXC1 forkhead box C1
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
GAN gigaxonin
GFOD1 glucose-fructose oxidoreductase domain containing 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GPR68 G protein-coupled receptor 68
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
IFT140 intraflagellar transport 140
IRF7 interferon regulatory factor 7
KLF3 Kruppel-like factor 3 (basic)
KREMEN2 kringle containing transmembrane protein 2
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAMLD1 mastermind-like domain containing 1
MAP1S microtubule-associated protein 1S
MBTD1 mbt domain containing 1
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NKAIN1 Na+/K+ transporting ATPase interacting 1
PARD6A par-6 family cell polarity regulator alpha
PGM1 phosphoglucomutase 1
PILRB paired immunoglobin-like type 2 receptor beta
PISD phosphatidylserine decarboxylase
PLD3 phospholipase D family, member 3
PRICKLE3 prickle homolog 3 (Drosophila)
RAB4B RAB4B, member RAS oncogene family
RECQL4 RecQ protein-like 4
REEP4 receptor accessory protein 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RNF123 ring finger protein 123
RPL13P5 ribosomal protein L13 pseudogene 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAI2 snail family zinc finger 2
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SRBD1 S1 RNA binding domain 1
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TMEM184C transmembrane protein 184C
TMEM212 transmembrane protein 212
TMEM57 transmembrane protein 57
TNRC6B trinucleotide repeat containing 6B
TPST1 tyrosylprotein sulfotransferase 1
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBG2 tubulin, gamma 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR47 WD repeat domain 47
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF35 zinc finger protein 35
ZNF408 zinc finger protein 408
ZNF611 zinc finger protein 611
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816