adaptive immune response Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory). (Gene Ontology, GO_0002250)
External Link http://amigo.geneontology.org/amigo/term/GO:0002250
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Genes

86 genes participating in the adaptive immune response biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
BCL10 B-cell CLL/lymphoma 10
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BMX BMX non-receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
CADM1 cell adhesion molecule 1
CD27 CD27 molecule
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CRTAM cytotoxic and regulatory T cell molecule
CTSC cathepsin C
CTSH cathepsin H
CTSL cathepsin L
CTSS cathepsin S
CXCL13 chemokine (C-X-C motif) ligand 13
DLG1 discs, large homolog 1 (Drosophila)
EBI3 Epstein-Barr virus induced 3
EMP2 epithelial membrane protein 2
EXO1 exonuclease 1
FAS Fas cell surface death receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GNL1 guanine nucleotide binding protein-like 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-E major histocompatibility complex, class I, E
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNG interferon, gamma
IFNK interferon, kappa
IFNW1 interferon, omega 1
IL12B interleukin 12B
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL4 interleukin 4
IRF7 interferon regulatory factor 7
ITK IL2-inducible T-cell kinase
JAG1 jagged 1
JAM3 junctional adhesion molecule 3
JCHAIN joining chain of multimeric IgA and IgM
KLHL6 kelch-like family member 6
LYST lysosomal trafficking regulator
MEF2C myocyte enhancer factor 2C
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MSH2 mutS homolog 2
MYO1G myosin IG
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PRKCD protein kinase C, delta
RAET1E retinoic acid early transcript 1E
RAG1 recombination activating gene 1
RIPK2 receptor-interacting serine-threonine kinase 2
SLA2 Src-like-adaptor 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SYK spleen tyrosine kinase
TEC tec protein tyrosine kinase
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR8 toll-like receptor 8
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TXK TXK tyrosine kinase
UNC13D unc-13 homolog D (C. elegans)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZP3 zona pellucida glycoprotein 3 (sperm receptor)