acute pancreatitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

290 genes co-occuring with the disease acute pancreatitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CCK cholecystokinin 2.28369
REG3A regenerating islet-derived 3 alpha 2.06668
PLA2G1B phospholipase A2, group IB (pancreas) 2.0047
SPINK1 serine peptidase inhibitor, Kazal type 1 1.96004
PRSS1 protease, serine, 1 (trypsin 1) 1.92858
CELA1 chymotrypsin-like elastase family, member 1 1.89917
CELA3B chymotrypsin-like elastase family, member 3B 1.87377
CRP C-reactive protein, pentraxin-related 1.86964
MPO myeloperoxidase 1.86415
PNLIP pancreatic lipase 1.84454
IL6 interleukin 6 1.71864
TMPRSS15 transmembrane protease, serine 15 1.70679
SST somatostatin 1.70542
TNF tumor necrosis factor 1.68997
CTSB cathepsin B 1.63052
CPB1 carboxypeptidase B1 (tissue) 1.56755
IL1B interleukin 1, beta 1.54407
CPA6 carboxypeptidase A6 1.51896
GCG glucagon 1.47198
CCKAR cholecystokinin A receptor 1.45836
LPL lipoprotein lipase 1.42016
IL10 interleukin 10 1.39214
ICAM1 intercellular adhesion molecule 1 1.36597
SOD2 superoxide dismutase 2, mitochondrial 1.31187
ALB albumin 1.29789
APOC2 apolipoprotein C-II 1.26255
KNG1 kininogen 1 1.2395
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 1.22995
RPAP2 RNA polymerase II associated protein 2 1.22258
ELANE elastase, neutrophil expressed 1.21695
TAC1 tachykinin, precursor 1 1.18023
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.17636
INS insulin 1.17421
LMF1 lipase maturation factor 1 1.17035
ASRGL1 asparaginase like 1 1.16435
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.16008
REG1A regenerating islet-derived 1 alpha 1.13585
TACR1 tachykinin receptor 1 1.12361
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.11856
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.11351
CLPS colipase, pancreatic 1.10594
VMP1 vacuole membrane protein 1 1.10048
CAT catalase 1.08202
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.0774
TLR4 toll-like receptor 4 1.05345
ALPPL2 alkaline phosphatase, placental-like 2 1.01891
APOA5 apolipoprotein A-V 1.01849
ALPP alkaline phosphatase, placental 1.01849
ALPL alkaline phosphatase, liver/bone/kidney 1.01807
KIAA0101 KIAA0101 1.01554
CXCL8 chemokine (C-X-C motif) ligand 8 1.00246
GPX5 glutathione peroxidase 5 0.958287
GPX4 glutathione peroxidase 4 0.954525
GPX1 glutathione peroxidase 1 0.937874
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.931656
CALCA calcitonin-related polypeptide alpha 0.928346
CCL2 chemokine (C-C motif) ligand 2 0.924213
CTRB2 chymotrypsinogen B2 0.917199
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.911022
HMGB1 high mobility group box 1 0.905675
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.89541
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.883111
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.877786
ERP27 endoplasmic reticulum protein 27 0.844621
PTAFR platelet-activating factor receptor 0.842982
IL18 interleukin 18 0.834378
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.831508
RNASEH2A ribonuclease H2, subunit A 0.825358
DNTT DNA nucleotidylexotransferase 0.824538
CTRC chymotrypsin C (caldecrin) 0.823308
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.817565
C5AR1 complement component 5a receptor 1 0.814693
CTRB1 chymotrypsinogen B1 0.812642
PRSS3 protease, serine, 3 0.812232
GHRL ghrelin/obestatin prepropeptide 0.802385
PTH parathyroid hormone 0.785984
BAX BCL2-associated X protein 0.784345
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.76921
NUPR1 nuclear protein, transcriptional regulator, 1 0.765943
OCLN occludin 0.759416
GGT1 gamma-glutamyltransferase 1 0.750457
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.743141
GRP gastrin-releasing peptide 0.727738
EDNRA endothelin receptor type A 0.72329
CXCL2 chemokine (C-X-C motif) ligand 2 0.716021
JUN jun proto-oncogene 0.714005
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.704742
LEP leptin 0.691495
PPY pancreatic polypeptide 0.690694
DPP4 dipeptidyl-peptidase 4 0.689492
MDH1 malate dehydrogenase 1, NAD (soluble) 0.689092
SELE selectin E 0.685091
SAT1 spermidine/spermine N1-acetyltransferase 1 0.658818
AMY2A amylase, alpha 2A (pancreatic) 0.656046
F2 coagulation factor II (thrombin) 0.65565
TREM1 triggering receptor expressed on myeloid cells 1 0.654463
GUSB glucuronidase, beta 0.643009
HMOX1 heme oxygenase 1 0.641039
IL36B interleukin 36, beta 0.639857
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.638676
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.62885
PLA2G10 phospholipase A2, group X 0.625711
CTH cystathionine gamma-lyase 0.622183
CARD17 caspase recruitment domain family, member 17 0.615138
CD4 CD4 molecule 0.61162
TGFB1 transforming growth factor, beta 1 0.609666
SGSM3 small G protein signaling modulator 3 0.607714
CEL carboxyl ester lipase 0.6003
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.59952
ACPP acid phosphatase, prostate 0.597961
XDH xanthine dehydrogenase 0.587444
NOS2 nitric oxide synthase 2, inducible 0.57655
MMP9 matrix metallopeptidase 9 0.576161
NACAD NAC alpha domain containing 0.572273
ACE angiotensin I converting enzyme 0.548195
PPARG peroxisome proliferator-activated receptor gamma 0.544705
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.53657
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.535409
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.533088
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.526518
HSPA4 heat shock 70kDa protein 4 0.523816
FASLG Fas ligand (TNF superfamily, member 6) 0.521888
SLC22A20 solute carrier family 22, member 20 0.521502
KLK1 kallikrein 1 0.520731
VIP vasoactive intestinal peptide 0.514571
CTSS cathepsin S 0.514186
STXBP3 syntaxin binding protein 3 0.510344
SKAP2 src kinase associated phosphoprotein 2 0.497703
RETN resistin 0.490835
PLG plasminogen 0.490454
F3 coagulation factor III (thromboplastin, tissue factor) 0.48893
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.485505
REG1B regenerating islet-derived 1 beta 0.480945
IL1RN interleukin 1 receptor antagonist 0.477151
TGM4 transglutaminase 4 0.468441
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.467306
GAST gastrin 0.454093
CELA3A chymotrypsin-like elastase family, member 3A 0.451454
GAL galanin/GMAP prepropeptide 0.449947
FN1 fibronectin 1 0.445429
PAAF1 proteasomal ATPase-associated factor 1 0.444676
MAPK8 mitogen-activated protein kinase 8 0.440162
EDN1 endothelin 1 0.436402
ESAM endothelial cell adhesion molecule 0.436026
ING1 inhibitor of growth family, member 1 0.436026
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.434148
MYLK2 myosin light chain kinase 2 0.431894
CPA1 carboxypeptidase A1 (pancreatic) 0.42664
LBP lipopolysaccharide binding protein 0.413527
DNAH8 dynein, axonemal, heavy chain 8 0.40904
TJP1 tight junction protein 1 0.408292
MGARP mitochondria-localized glutamic acid-rich protein 0.406798
HCAR1 hydroxycarboxylic acid receptor 1 0.406051
POMC proopiomelanocortin 0.402692
TF transferrin 0.39598
SH3GL1 SH3-domain GRB2-like 1 0.39598
CPA2 carboxypeptidase A2 (pancreatic) 0.393374
SELL selectin L 0.391885
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.387423
RPAIN RPA interacting protein 0.384451
TTR transthyretin 0.382966
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.380368
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.380368
TACR2 tachykinin receptor 2 0.37555
MRPL13 mitochondrial ribosomal protein L13 0.370737
TIGAR TP53 induced glycolysis regulatory phosphatase 0.367779
AQP12A aquaporin 12A 0.366671
PRKD1 protein kinase D1 0.366671
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.366301
XBP1 X-box binding protein 1 0.365193
IRAK4 interleukin-1 receptor-associated kinase 4 0.360395
PAOX polyamine oxidase (exo-N4-amino) 0.358551
PLA2G12B phospholipase A2, group XIIB 0.358551
SLC39A5 solute carrier family 39 (zinc transporter), member 5 0.357077
EGR1 early growth response 1 0.356341
AHCYL2 adenosylhomocysteinase-like 2 0.344574
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.343106
IL1R1 interleukin 1 receptor, type I 0.338707
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.33651
GPBAR1 G protein-coupled bile acid receptor 1 0.335778
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.333583
TCHH trichohyalin 0.327375
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.323002
PYY peptide YY 0.322273
CPA5 carboxypeptidase A5 0.321909
B2M beta-2-microglobulin 0.320454
PIAS1 protein inhibitor of activated STAT, 1 0.312102
IGF1 insulin-like growth factor 1 (somatomedin C) 0.307033
PARP1 poly (ADP-ribose) polymerase 1 0.305948
RPS13 ribosomal protein S13 0.304503
PDIA5 protein disulfide isomerase family A, member 5 0.30342
CCL13 chemokine (C-C motif) ligand 13 0.302698
KAT5 K(lysine) acetyltransferase 5 0.300533
AQP1 aquaporin 1 (Colton blood group) 0.299092
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.297651
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.290821
GP2 glycoprotein 2 (zymogen granule membrane) 0.290462
GLP1R glucagon-like peptide 1 receptor 0.280439
HSPA1A heat shock 70kDa protein 1A 0.278297
HAND2 heart and neural crest derivatives expressed 2 0.277227
FGL2 fibrinogen-like 2 0.277227
ABR active BCR-related 0.275801
CCL3 chemokine (C-C motif) ligand 3 0.275089
LTF lactotransferrin 0.271886
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.27153
GGT2 gamma-glutamyltransferase 2 0.270108
LAMP2 lysosomal-associated membrane protein 2 0.269753
PTF1A pancreas specific transcription factor, 1a 0.267267
CLDN7 claudin 7 0.264785
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.26266
RRBP1 ribosome binding protein 1 0.262306
FOS FBJ murine osteosarcoma viral oncogene homolog 0.260891
ECRP ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene 0.257711
MGLL monoglyceride lipase 0.256299
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.255946
HMX1 H6 family homeobox 1 0.254536
STRBP spermatid perinuclear RNA binding protein 0.252422
SOBP sine oculis binding protein homolog (Drosophila) 0.251718
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.24996
ANGPT2 angiopoietin 2 0.248554
BTG2 BTG family, member 2 0.248203
NPS neuropeptide S 0.246098
CAPN2 calpain 2, (m/II) large subunit 0.243995
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 0.242595
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.241196
MMD2 monocyte to macrophage differentiation-associated 2 0.241196
NCR3 natural cytotoxicity triggering receptor 3 0.239799
JAK1 Janus kinase 1 0.23945
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.238752
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.236312
IL15 interleukin 15 0.227988
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.219057
APEH acylaminoacyl-peptide hydrolase 0.218715
MLKL mixed lineage kinase domain-like 0.215314
TP53 tumor protein p53 0.212945
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.211934
AHCYL1 adenosylhomocysteinase-like 1 0.210589
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.208579
PPCS phosphopantothenoylcysteine synthetase 0.208579
HYOU1 hypoxia up-regulated 1 0.206913
FGF1 fibroblast growth factor 1 (acidic) 0.20658
VCAM1 vascular cell adhesion molecule 1 0.205916
NASP nuclear autoantigenic sperm protein (histone-binding) 0.200331
LMTK2 lemur tyrosine kinase 2 0.200006
CCR1 chemokine (C-C motif) receptor 1 0.199356
IAPP islet amyloid polypeptide 0.198064
RBM8A RNA binding motif protein 8A 0.197099
GHSR growth hormone secretagogue receptor 0.194865
LUM lumican 0.194232
A1BG alpha-1-B glycoprotein 0.194232
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.193285
CDC16 cell division cycle 16 0.190786
CD69 CD69 molecule 0.189859
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.188632
NOS1 nitric oxide synthase 1 (neuronal) 0.18591
ERN1 endoplasmic reticulum to nucleus signaling 1 0.184128
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.182666
CD40LG CD40 ligand 0.182375
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.18151
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.179239
DOCK5 dedicator of cytokinesis 5 0.178126
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.177301
ACE2 angiotensin I converting enzyme 2 0.177029
DOCK2 dedicator of cytokinesis 2 0.177029
PTHLH parathyroid hormone-like hormone 0.175947
CLDN1 claudin 1 0.175947
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.172038
SAA1 serum amyloid A1 0.171286
AMBP alpha-1-microglobulin/bikunin precursor 0.168381
NLRP3 NLR family, pyrin domain containing 3 0.167915
HRAS Harvey rat sarcoma viral oncogene homolog 0.166995
HEBP1 heme binding protein 1 0.165001
SLC38A5 solute carrier family 38, member 5 0.163938
TLR2 toll-like receptor 2 0.163111
CNR1 cannabinoid receptor 1 (brain) 0.161912
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.161716
GALR3 galanin receptor 3 0.161523
WAPAL wings apart-like homolog (Drosophila) 0.161523
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.161331
MAPK14 mitogen-activated protein kinase 14 0.160761
PARD3 par-3 family cell polarity regulator 0.160574
BSG basigin (Ok blood group) 0.160574
NAMPT nicotinamide phosphoribosyltransferase 0.160574
HP haptoglobin 0.160021
CPA3 carboxypeptidase A3 (mast cell) 0.159302
PTK7 protein tyrosine kinase 7 (inactive) 0.159302
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.159124
PRRX1 paired related homeobox 1 0.158951
TRH thyrotropin-releasing hormone 0.158778
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.157929