acute monocytic leukemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_8864)
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Genes

167 genes co-occuring with the disease acute monocytic leukemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
KAT6A K(lysine) acetyltransferase 6A 1.36989
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 1.25428
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 1.2495
LYZ lysozyme 1.22909
CD300LF CD300 molecule-like family member f 1.12825
MYB v-myb avian myeloblastosis viral oncogene homolog 1.1253
ZNF580 zinc finger protein 580 1.11898
CD33 CD33 molecule 1.11687
CLP1 cleavage and polyadenylation factor I subunit 1 1.08327
RBM12 RNA binding motif protein 12 1.06564
KIAA0100 KIAA0100 1.02229
RPP21 ribonuclease P/MRP 21kDa subunit 1.0168
CAB39L calcium binding protein 39-like 0.996127
SH3GL1 SH3-domain GRB2-like 1 0.994017
EP300 E1A binding protein p300 0.952856
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.942027
FLT3 fms-related tyrosine kinase 3 0.912668
MYO1F myosin IF 0.908142
TRIM39-RPP21 TRIM39-RPP21 readthrough 0.898693
NCAM1 neural cell adhesion molecule 1 0.892948
NCKIPSD NCK interacting protein with SH3 domain 0.867959
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.851583
ELL elongation factor RNA polymerase II 0.849126
KMT2A lysine (K)-specific methyltransferase 2A 0.844621
CD68 CD68 molecule 0.830689
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.783116
F3 coagulation factor III (thromboplastin, tissue factor) 0.776568
MPO myeloperoxidase 0.745172
CD9 CD9 molecule 0.741111
TLR4 toll-like receptor 4 0.731786
NOMO1 NODAL modulator 1 0.708364
MFSD10 major facilitator superfamily domain containing 10 0.681894
NUP98 nucleoporin 98kDa 0.66914
HIST1H2AJ histone cluster 1, H2aj 0.665166
HIST1H2AD histone cluster 1, H2ad 0.665166
H2AFV H2A histone family, member V 0.663181
H2AFB2 H2A histone family, member B2 0.662784
H2AFB1 H2A histone family, member B1 0.661594
H2AFY2 H2A histone family, member Y2 0.661197
HIST1H2AH histone cluster 1, H2ah 0.660404
H2AFJ H2A histone family, member J 0.660404
HIST1H2AM histone cluster 1, H2am 0.656441
CREBBP CREB binding protein 0.654463
HIST1H2AB histone cluster 1, H2ab 0.650903
HIST1H2AE histone cluster 1, H2ae 0.650903
HIST1H2AG histone cluster 1, H2ag 0.643404
NCOA2 nuclear receptor coactivator 2 0.640251
ANXA2 annexin A2 0.63907
PGM1 phosphoglucomutase 1 0.637495
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.631991
SCARB2 scavenger receptor class B, member 2 0.631598
CD34 CD34 molecule 0.629635
H2AFY H2A histone family, member Y 0.617486
CD36 CD36 molecule (thrombospondin receptor) 0.615529
CD22 CD22 molecule 0.583941
SCARB1 scavenger receptor class B, member 1 0.57305
TNF tumor necrosis factor 0.571107
LY96 lymphocyte antigen 96 0.570329
MYD88 myeloid differentiation primary response 88 0.564112
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 0.556732
CCL2 chemokine (C-C motif) ligand 2 0.533861
CD19 CD19 molecule 0.524202
PRODH proline dehydrogenase (oxidase) 1 0.522659
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.51534
GPX7 glutathione peroxidase 7 0.514956
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.511496
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.511496
SEPT6 septin 6 0.508041
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.491978
FER fer (fps/fes related) tyrosine kinase 0.491978
CIRBP cold inducible RNA binding protein 0.490072
TK1 thymidine kinase 1, soluble 0.48893
HOXA4 homeobox A4 0.478668
AGO2 argonaute RISC catalytic component 2 0.476014
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.472604
BCL2L12 BCL2-like 12 (proline rich) 0.471468
OAT ornithine aminotransferase 0.454847
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.454847
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.454093
TRAF4 TNF receptor-associated factor 4 0.453339
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.450701
TIMD4 T-cell immunoglobulin and mucin domain containing 4 0.448817
ANXA5 annexin A5 0.446935
CD7 CD7 molecule 0.439034
NME1-NME2 NME1-NME2 readthrough 0.421016
CD44 CD44 molecule (Indian blood group) 0.418768
DOT1L DOT1-like histone H3K79 methyltransferase 0.418768
DCTD dCMP deaminase 0.41465
CD163 CD163 molecule 0.412779
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.407172
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.406798
MAPK7 mitogen-activated protein kinase 7 0.403438
EPS15 epidermal growth factor receptor pathway substrate 15 0.391513
PDCD5 programmed cell death 5 0.386308
CD1A CD1a molecule 0.385565
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.384451
VCAM1 vascular cell adhesion molecule 1 0.377773
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.37629
CD4 CD4 molecule 0.364085
IL1B interleukin 1, beta 0.360026
THBD thrombomodulin 0.359289
GPHN gephyrin 0.357077
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.354868
PTPRJ protein tyrosine phosphatase, receptor type, J 0.350084
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.350084
PHF6 PHD finger protein 6 0.348246
CD14 CD14 molecule 0.33944
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.333583
HMGB2 high mobility group box 2 0.329565
RARA retinoic acid receptor, alpha 0.325916
GPC1 glypican 1 0.324823
TOP2B topoisomerase (DNA) II beta 180kDa 0.317182
JUN jun proto-oncogene 0.315003
CD86 CD86 molecule 0.315003
DHFR dihydrofolate reductase 0.309928
IRAK3 interleukin-1 receptor-associated kinase 3 0.305948
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.303059
CXCL8 chemokine (C-X-C motif) ligand 8 0.303059
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.301976
TFRC transferrin receptor 0.300894
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.300533
CCL25 chemokine (C-C motif) ligand 25 0.291539
PREB prolactin regulatory element binding 0.276158
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.270819
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.266558
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.257711
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.255594
SELE selectin E 0.254536
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.246448
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.242595
YARS tyrosyl-tRNA synthetase 0.238403
CCL1 chemokine (C-C motif) ligand 1 0.237357
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.237357
FXYD1 FXYD domain containing ion transport regulator 1 0.237009
SEPT9 septin 9 0.231102
CD37 CD37 molecule 0.228333
LAMB3 laminin, beta 3 0.22454
IRAK4 interleukin-1 receptor-associated kinase 4 0.223853
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.22145
DNTT DNA nucleotidylexotransferase 0.215992
NCOR1 nuclear receptor corepressor 1 0.214975
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.214297
IL6 interleukin 6 0.213283
CD38 CD38 molecule 0.205254
FMOD fibromodulin 0.203933
PLAUR plasminogen activator, urokinase receptor 0.203933
BBC3 BCL2 binding component 3 0.202946
CFI complement factor I 0.198709
SEPT5 septin 5 0.197099
CD80 CD80 molecule 0.188938
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.185612
IL12B interleukin 12B 0.178126
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.177301
JMJD6 jumonji domain containing 6 0.177029
HLA-A major histocompatibility complex, class I, A 0.175947
CD48 CD48 molecule 0.170789
BAX BCL2-associated X protein 0.170054
LTB4R leukotriene B4 receptor 0.168148
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.168148
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.166995
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.166095
KLK6 kallikrein-related peptidase 6 0.161912
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.160948
PICALM phosphatidylinositol binding clathrin assembly protein 0.160387
TLR8 toll-like receptor 8 0.158266
TLR2 toll-like receptor 2 0.158266
PTPRC protein tyrosine phosphatase, receptor type, C 0.157765