acute megakaryocytic leukemia cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Acute megakaryocytic leukemia is a rare subtype of acute myeloid leukemia evolving from primitive megakaryoblasts. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001000)
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Genes

61 proteins co-occuring with the tissue acute megakaryocytic leukemia cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
MPL MPL proto-oncogene, thrombopoietin receptor 1.33274
THPO thrombopoietin 1.29085
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.27157
IL3 interleukin 3 1.25771
TUBB1 tubulin, beta 1 class VI 1.21624
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.966793
PTK2B protein tyrosine kinase 2 beta 0.946517
FAM134B family with sequence similarity 134, member B 0.942645
KITLG KIT ligand 0.902424
PTPRU protein tyrosine phosphatase, receptor type, U 0.900296
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.881204
RAB27B RAB27B, member RAS oncogene family 0.861363
FERMT3 fermitin family member 3 0.81983
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.801459
TLN1 talin 1 0.778986
CDA cytidine deaminase 0.766125
TUBB tubulin, beta class I 0.737618
NFYA nuclear transcription factor Y, alpha 0.717882
PF4 platelet factor 4 0.711319
SETD2 SET domain containing 2 0.667215
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.600881
MX2 MX dynamin-like GTPase 2 0.597263
MST1 macrophage stimulating 1 0.588431
RAP1A RAP1A, member of RAS oncogene family 0.580017
GP9 glycoprotein IX (platelet) 0.548517
CBS cystathionine-beta-synthase 0.547724
PTK2 protein tyrosine kinase 2 0.532274
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.531484
JAK2 Janus kinase 2 0.531089
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.506279
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.50471
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.49844
GP6 glycoprotein VI (platelet) 0.489838
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.486326
GNLY granulysin 0.485935
MATK megakaryocyte-associated tyrosine kinase 0.484766
RAB27A RAB27A, member RAS oncogene family 0.480091
VIPR1 vasoactive intestinal peptide receptor 1 0.4576
RHOB ras homolog family member B 0.456828
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.43414
IL6 interleukin 6 0.432225
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.421148
USF1 upstream transcription factor 1 0.411631
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.396087
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.390421
IL6R interleukin 6 receptor 0.384013
CTTN cortactin 0.381379
IL1A interleukin 1, alpha 0.379875
DCK deoxycytidine kinase 0.377621
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.351485
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.344449
JAK3 Janus kinase 3 0.332294
FAAH fatty acid amide hydrolase 0.319134
HBG2 hemoglobin, gamma G 0.309697
CD34 CD34 molecule 0.295297
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.271604
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.258917
JAK1 Janus kinase 1 0.25259
FGFR3 fibroblast growth factor receptor 3 0.246442
PLCG1 phospholipase C, gamma 1 0.243294
EPOR erythropoietin receptor 0.23781