acute coronary syndrome Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A disorder characterized by signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction. (Experimental Factor Ontology, EFO_0005672)
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Genes

47 genes associated with the disease acute coronary syndrome in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE2 angiotensin I converting enzyme 2
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
APOB apolipoprotein B
APOE apolipoprotein E
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
CD40 CD40 molecule, TNF receptor superfamily member 5
CETP cholesteryl ester transfer protein, plasma
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
F12 coagulation factor XII (Hageman factor)
F3 coagulation factor III (thromboplastin, tissue factor)
FGB fibrinogen beta chain
FTO fat mass and obesity associated
GP6 glycoprotein VI (platelet)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IFNG interferon, gamma
IL10 interleukin 10
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LDLR low density lipoprotein receptor
MMP9 matrix metallopeptidase 9
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PCSK9 proprotein convertase subtilisin/kexin type 9
PGBD1 piggyBac transposable element derived 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
SLCO1B1 solute carrier organic anion transporter family, member 1B1
THBD thrombomodulin
TLR4 toll-like receptor 4
TNFRSF4 tumor necrosis factor receptor superfamily, member 4