acute coronary syndrome; Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A disorder characterized by signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction. (Experimental Factor Ontology, EFO_0005672)
Similar Terms
Downloads & Tools

Genes

75 genes associated with the disease acute coronary syndrome; in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACE angiotensin I converting enzyme
ADD1 adducin 1 (alpha)
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOA1 apolipoprotein A-I
APOE apolipoprotein E
ARHGAP35 Rho GTPase activating protein 35
BDKRB2 bradykinin receptor B2
CCL11 chemokine (C-C motif) ligand 11
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD40 CD40 molecule, TNF receptor superfamily member 5
CETP cholesteryl ester transfer protein, plasma
COMT catechol-O-methyltransferase
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYBA cytochrome b-245, alpha polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
EGFR epidermal growth factor receptor
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGB fibrinogen beta chain
GAS6 growth arrest-specific 6
GJA4 gap junction protein, alpha 4, 37kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HFE hemochromatosis
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IL1B interleukin 1, beta
IL6 interleukin 6
IRF5 interferon regulatory factor 5
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LIPC lipase, hepatic
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LTA lymphotoxin alpha
MGP matrix Gla protein
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MTFP1 mitochondrial fission process 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PON1 paraoxonase 1
PON2 paraoxonase 2
PPARG peroxisome proliferator-activated receptor gamma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBD thrombomodulin
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
THPO thrombopoietin
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
WRN Werner syndrome, RecQ helicase-like